The role of peroxisome proliferator-activated receptors in carcinogenesis and chemoprevention JM Peters, YM Shah, FJ Gonzalez Nature Reviews Cancer 12 (3), 181-195, 2012 | 502 | 2012 |
Intestinal hypoxia-inducible transcription factors are essential for iron absorption following iron deficiency YM Shah, T Matsubara, S Ito, SH Yim, FJ Gonzalez Cell metabolism 9 (2), 152-164, 2009 | 484 | 2009 |
Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice I Kim, K Morimura, Y Shah, Q Yang, JM Ward, FJ Gonzalez Carcinogenesis 28 (5), 940-946, 2007 | 378 | 2007 |
CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4 P Liao, W Wang, W Wang, I Kryczek, X Li, Y Bian, A Sell, S Wei, S Grove, ... Cancer cell 40 (4), 365-378. e6, 2022 | 351 | 2022 |
Disruption of hypoxia-inducible factor 1 in adipocytes improves insulin sensitivity and decreases adiposity in high-fat diet–fed mice C Jiang, A Qu, T Matsubara, T Chanturiya, W Jou, O Gavrilova, YM Shah, ... Diabetes 60 (10), 2484-2495, 2011 | 316 | 2011 |
PPARα: mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators FJ Gonzalez, YM Shah Toxicology 246 (1), 2-8, 2008 | 315 | 2008 |
Peroxisome Proliferator-Activated Receptor α Regulates a MicroRNA-Mediated Signaling Cascade Responsible for Hepatocellular Proliferation YM Shah, K Morimura, Q Yang, T Tanabe, M Takagi, FJ Gonzalez Molecular and cellular biology 27 (12), 4238-4247, 2007 | 312 | 2007 |
Hypoxia-inducible factor-1α regulates β cell function in mouse and human islets K Cheng, K Ho, R Stokes, C Scott, SM Lau, WJ Hawthorne, PJ O’connell, ... The Journal of clinical investigation 120 (6), 2171-2183, 2010 | 296 | 2010 |
Hypoxia-inducible factor-2α mediates the adaptive increase of intestinal ferroportin during iron deficiency in mice M Taylor, A Qu, ER Anderson, T Matsubara, A Martin, FJ Gonzalez, ... Gastroenterology 140 (7), 2044-2055, 2011 | 285 | 2011 |
Iron homeostasis in the liver ER Anderson, YM Shah Comprehensive Physiology 3 (1), 315, 2013 | 275 | 2013 |
Pregnane X receptor activation ameliorates DSS-induced inflammatory bowel disease via inhibition of NF-κB target gene expression YM Shah, X Ma, K Morimura, I Kim, FJ Gonzalez American Journal of Physiology-Gastrointestinal and Liver Physiology 292 (4 …, 2007 | 271 | 2007 |
Peroxisome proliferator activated receptor γ in colonic epithelial cells protects against experimental inflammatory bowel disease M Adachi, R Kurotani, K Morimura, Y Shah, M Sanford, BB Madison, ... Gut 55 (8), 1104-1113, 2006 | 263 | 2006 |
Oxygen battle in the gut: Hypoxia and hypoxia-inducible factors in metabolic and inflammatory responses in the intestine R Singhal, YM Shah Journal of Biological Chemistry 295 (30), 10493-10505, 2020 | 235 | 2020 |
Microbial metabolite signaling is required for systemic iron homeostasis NK Das, AJ Schwartz, G Barthel, N Inohara, Q Liu, A Sankar, DR Hill, ... Cell metabolism 31 (1), 115-130. e6, 2020 | 210 | 2020 |
Endothelial PAS domain protein 1 activates the inflammatory response in the intestinal epithelium to promote colitis in mice X Xue, S Ramakrishnan, E Anderson, M Taylor, EM Zimmermann, ... Gastroenterology 145 (4), 831-841, 2013 | 207 | 2013 |
Iron uptake via DMT1 integrates cell cycle with JAK-STAT3 signaling to promote colorectal tumorigenesis X Xue, SK Ramakrishnan, K Weisz, D Triner, L Xie, D Attili, A Pant, ... Cell metabolism 24 (3), 447-461, 2016 | 200 | 2016 |
Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1 H Zhang, SK Ramakrishnan, D Triner, B Centofanti, D Maitra, B Győrffy, ... Science signaling 8 (397), ra98-ra98, 2015 | 196 | 2015 |
Serum metabolomics reveals irreversible inhibition of fatty acid β-oxidation through the suppression of PPARα activation as a contributing mechanism of acetaminophen-induced … C Chen, KW Krausz, YM Shah, JR Idle, FJ Gonzalez Chemical research in toxicology 22 (4), 699-707, 2009 | 195 | 2009 |
Therapeutic role of rifaximin in inflammatory bowel disease: clinical implication of human pregnane X receptor activation J Cheng, YM Shah, X Ma, X Pang, T Tanaka, T Kodama, KW Krausz, ... Journal of Pharmacology and Experimental Therapeutics 335 (1), 32-41, 2010 | 193 | 2010 |
Hypoxia-inducible factor augments experimental colitis through an MIF–dependent inflammatory signaling cascade YM Shah, S Ito, K Morimura, C Chen, SH Yim, VH Haase, FJ Gonzalez Gastroenterology 134 (7), 2036-2048. e3, 2008 | 193 | 2008 |