| Phase I and biomarker study of OPB-51602, a novel signal transducer and activator of transcription (STAT) 3 inhibitor, in patients with refractory solid malignancies AL Wong, RA Soo, DS Tan, SC Lee, JS Lim, PC Marban, LR Kong, ... Annals of Oncology 26 (5), 998-1005, 2015 | 188 | 2015 |
| Anti-malarial drug artesunate attenuates experimental allergic asthma via inhibition of the phosphoinositide 3-kinase/Akt pathway C Cheng, WE Ho, FY Goh, SP Guan, LR Kong, WQ Lai, BP Leung, ... PLoS One 6 (6), e20932, 2011 | 133 | 2011 |
| Targeting metabolism in cancer cells and the tumour microenvironment for cancer therapy J Li, JQ Eu, LR Kong, L Wang, YC Lim, BC Goh, ALA Wong Molecules 25 (20), 4831, 2020 | 121 | 2020 |
| Metabolic reprogramming of oncogene-addicted cancer cells to OXPHOS as a mechanism of drug resistance J Hirpara, JQ Eu, JKM Tan, AL Wong, MV Clement, LR Kong, N Ohi, ... Redox biology 25, 101076, 2019 | 98 | 2019 |
| Pan-HDAC inhibition by panobinostat mediates chemosensitization to carboplatin in non-small cell lung cancer via attenuation of EGFR signaling L Wang, NLX Syn, VV Subhash, Y Any, WL Thuya, ESH Cheow, L Kong, ... Cancer letters 417, 152-160, 2018 | 71 | 2018 |
| Protective role of 14-deoxy-11, 12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation SP Guan, LR Kong, C Cheng, JCW Lim, WSF Wong Journal of natural products 74 (6), 1484-1490, 2011 | 61 | 2011 |
| MEK inhibition overcomes cisplatin resistance conferred by SOS/MAPK pathway activation in squamous cell carcinoma LR Kong, KN Chua, WJ Sim, HC Ng, C Bi, J Ho, ME Nga, YH Pang, ... Molecular cancer therapeutics 14 (7), 1750-1760, 2015 | 58 | 2015 |
| A novel combinatorial strategy using Seliciclib® and Belinostat® for eradication of non-small cell lung cancer via apoptosis induction and BID activation PS Ong, L Wang, DMH Chia, JYX Seah, LR Kong, WL Thuya, ... Cancer letters 381 (1), 49-57, 2016 | 48 | 2016 |
| DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death HB Low, ZL Wong, B Wu, LR Kong, CW Png, YL Cho, CW Li, F Xiao, X Xin, ... Nature Communications 12 (1), 2284, 2021 | 35 | 2021 |
| Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation LR Kong, RW Ong, TZ Tan, NAB Mohamed Salleh, M Thangavelu, ... Nature Communications 11 (1), 2086, 2020 | 32 | 2020 |
| Pan-CDK inhibition augments cisplatin lethality in nasopharyngeal carcinoma cell lines and xenograft models NL Syn, PL Lim, LR Kong, L Wang, ALA Wong, CM Lim, TKS Loh, ... Signal Transduction and Targeted Therapy 3 (1), 9, 2018 | 32 | 2018 |
| Belinostat exerts antitumor cytotoxicity through the ubiquitin‐proteasome pathway in lung squamous cell carcinoma LR Kong, TZ Tan, WR Ong, C Bi, H Huynh, SC Lee, WJ Chng, ... Molecular oncology 11 (8), 965-980, 2017 | 32 | 2017 |
| Quantification of L‐ergothioneine in human plasma and erythrocytes by liquid chromatography‐tandem mass spectrometry LZ Wang, WL Thuya, DSL Toh, MGL Lie, JYA Lau, LR Kong, SC Wan, ... Journal of Mass Spectrometry 48 (3), 406-412, 2013 | 27 | 2013 |
| Combinatorial treatment using targeted MEK and SRC inhibitors synergistically abrogates tumor cell growth and induces mesenchymal-epithelial transition in non-small-cell lung … KN Chua, LR Kong, WJ Sim, HC Ng, WR Ong, JP Thiery, H Huynh, ... Oncotarget 6 (30), 29991, 2015 | 23 | 2015 |
| A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma LR Kong, NAB Mohamed Salleh, RW Ong, TZ Tan, NL Syn, RM Goh, ... Nature communications 11 (1), 1556, 2020 | 22 | 2020 |
| Simultaneous determination of raltegravir and raltegravir glucuronide in human plasma by liquid chromatography–tandem mass spectrometric method LZ Wang, LSU Lee, WL Thuya, GH Soon, LR Kong, PL Nye, ... Journal of mass spectrometry 46 (2), 202-208, 2011 | 22 | 2011 |
| Sustained IKKβ phosphorylation and NF-κB activation by superoxide-induced peroxynitrite-mediated nitrotyrosine modification of B56γ3 and PP2A inactivation YH Yee, SJF Chong, LR Kong, BC Goh, S Pervaiz Redox biology 41, 101834, 2021 | 21 | 2021 |
| Integration of antiangiogenic therapy with cisplatin and gemcitabine chemotherapy in patients with nasopharyngeal carcinoma WQ Chong, CM Lim, AK Sinha, CS Tan, GHJ Chan, Y Huang, ... Clinical Cancer Research 26 (20), 5320-5328, 2020 | 19 | 2020 |
| FAM3C in circulating tumor-derived extracellular vesicles promotes non-small cell lung cancer growth in secondary sites WL Thuya, LR Kong, NL Syn, LW Ding, ESH Cheow, RTX Wong, T Wang, ... Theranostics 13 (2), 621, 2023 | 13 | 2023 |
| A glycolytic metabolite bypasses “two-hit” tumor suppression by BRCA2 LR Kong, K Gupta, AJ Wu, D Perera, R Ivanyi-Nagy, SM Ahmed, TZ Tan, ... Cell 187 (9), 2269-2287. e16, 2024 | 7 | 2024 |
