A human herpesvirus miRNA attenuates interferon signaling and contributes to maintenance of viral latency by targeting IKKɛ D Liang, Y Gao, X Lin, Z He, Q Zhao, Q Deng, K Lan Cell research 21 (5), 793-806, 2011 | 154 | 2011 |
miR-K12-7-5p encoded by Kaposi's sarcoma-associated herpesvirus stabilizes the latent state by targeting viral ORF50/RTA X Lin, D Liang, Z He, Q Deng, ES Robertson, K Lan PloS one 6 (1), e16224, 2011 | 151 | 2011 |
Latency-associated nuclear antigen of kaposi sarcoma–associated herpesvirus promotes angiogenesis through targeting notch signaling effector Hey1 X Wang, Z He, T Xia, X Li, D Liang, X Lin, H Wen, K Lan Cancer research 74 (7), 2026-2037, 2014 | 51 | 2014 |
A two-amino-acid substitution in the transcription factor RORγt disrupts its function in TH17 differentiation but not in thymocyte development Z He, J Ma, R Wang, J Zhang, Z Huang, F Wang, S Sen, EV Rothenberg, ... Nature Immunology 18 (10), 1128-1138, 2017 | 46 | 2017 |
SRC1 promotes Th17 differentiation by overriding Foxp3 suppression to stimulate RORγt activity in a PKC-θ–dependent manner S Sen, F Wang, J Zhang, Z He, J Ma, Y Gwack, J Xu, Z Sun Proceedings of the National Academy of Sciences 115 (3), E458-E467, 2018 | 36 | 2018 |
Murine gammaherpesvirus 68 evades host cytokine production via replication transactivator-induced RelA degradation X Dong, Z He, D Durakoglugil, L Arneson, Y Shen, P Feng Journal of virology 86 (4), 1930-1941, 2012 | 36 | 2012 |
Ubiquitination of RORγt at lysine 446 limits Th17 differentiation by controlling coactivator recruitment Z He, F Wang, J Ma, S Sen, J Zhang, Y Gwack, Y Zhou, Z Sun The Journal of Immunology 197 (4), 1148-1158, 2016 | 33 | 2016 |
Cellular corepressor TLE2 inhibits replication-and-transcription-activator-mediated transactivation and lytic reactivation of Kaposi's sarcoma-associated herpesvirus Z He, Y Liu, D Liang, Z Wang, ES Robertson, K Lan Journal of virology 84 (4), 2047-2062, 2010 | 30 | 2010 |
Oncogenic herpesvirus KSHV Hijacks BMP-Smad1-Id signaling to promote tumorigenesis D Liang, H Hu, S Li, J Dong, X Wang, Y Wang, L He, Z He, Y Gao, SJ Gao, ... PLoS Pathogens 10 (7), e1004253, 2014 | 29 | 2014 |
Inhibition of KSHV infected primary effusion lymphomas in NOD/SCID mice by γ-secretase inhibitor K Lan, M Murakami, B Bajaj, R Kaul, Z He, R Gan, M Feldman, ... Cancer biology & therapy 8 (22), 2136-2143, 2009 | 29 | 2009 |
PRMT1 plays a critical role in Th17 differentiation by regulating reciprocal recruitment of STAT3 and STAT5 S Sen, Z He, S Ghosh, KJ Dery, L Yang, J Zhang, Z Sun The Journal of Immunology 201 (2), 440-450, 2018 | 28 | 2018 |
Sumoylation of RORγt regulates TH17 differentiation and thymocyte development Z He, J Zhang, Z Huang, Q Du, N Li, Q Zhang, Y Chen, Z Sun Nature Communications 9 (1), 4870, 2018 | 27 | 2018 |
Regulation of Th17 differentiation by IKKα-dependent and-independent phosphorylation of RORγt Z He, F Wang, J Zhang, S Sen, Q Pang, S Luo, Y Gwack, Z Sun The Journal of Immunology 199 (3), 955-964, 2017 | 27 | 2017 |
Fine-tuning of the Kaposi’s sarcoma-associated herpesvirus life cycle in neighboring cells through the RTA-JAG1-Notch pathway S Li, H Hu, Z He, D Liang, R Sun, K Lan PLoS Pathogens 12 (10), e1005900, 2016 | 26 | 2016 |
TCF-1 inhibits IL-17 gene expression to restrain Th17 immunity in a stage-specific manner J Zhang, Z He, S Sen, F Wang, Q Zhang, Z Sun The Journal of Immunology 200 (10), 3397-3406, 2018 | 24 | 2018 |
NF-κB activation coordinated by IKKβ and IKKε enables latent infection of Kaposi's sarcoma-associated herpesvirus Z He, J Zhao, J Zhang, JU Jung, P Feng Journal of virology 88 (1), 444-455, 2014 | 23 | 2014 |
Carboxyl-terminal amino acids 1052 to 1082 of the latency-associated nuclear antigen (LANA) interact with RBP-Jκ and are responsible for LANA-mediated RTA repression Y Jin, Z He, D Liang, Q Zhang, H Zhang, Q Deng, ES Robertson, K Lan Journal of virology 86 (9), 4956-4969, 2012 | 22 | 2012 |
SRC3 is a cofactor for RORγt in Th17 differentiation but not thymocyte development Z He, J Zhang, Q Du, J Xu, Y Gwack, Z Sun The Journal of Immunology 202 (3), 760-769, 2019 | 16 | 2019 |
Distinct inflammatory Th17 subsets emerge in autoimmunity and infection RJ Bouch, J Zhang, BC Miller, CJ Robbins, TH Mosher, W Li, ... Journal of Experimental Medicine 220 (10), e20221911, 2023 | 9 | 2023 |
Decoupling the role of RORγt in the differentiation and effector function of TH17 cells X Zhong, H Wu, W Zhang, Y Gwack, W Shang, KO Lee, N Isakov, Z He, ... Science advances 8 (42), eadc9221, 2022 | 6 | 2022 |