A Pathogenic Role for Myelin-Specific Cd8+ T Cells in a Model for Multiple Sclerosis ES Huseby, D Liggitt, T Brabb, B Schnabel, C Öhlén, J Goverman The Journal of experimental medicine 194 (5), 669-676, 2001 | 838 | 2001 |
Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection NJ Tubo, AJ Pagán, JJ Taylor, RW Nelson, JL Linehan, JM Ertelt, ... Cell 153 (4), 785-796, 2013 | 537 | 2013 |
Granulocyte-macrophage colony-stimulating factor: an effective adjuvant for protein and peptide-based vaccines ML Disis, H Bernhard, FM Shiota, SL Hand, JR Gralow, ES Huseby, ... | 424 | 1996 |
How the T cell repertoire becomes peptide and MHC specific ES Huseby, J White, F Crawford, T Vass, D Becker, C Pinilla, P Marrack, ... Cell 122 (2), 247-260, 2005 | 386 | 2005 |
IL-6–gp130–STAT3 in T cells directs the development of IL-17+ Th with a minimum effect on that of Treg in the steady state M Nishihara, H Ogura, N Ueda, M Tsuruoka, C Kitabayashi, F Tsuji, ... International immunology 19 (6), 695-702, 2007 | 338 | 2007 |
Structural biology of the T-cell receptor: insights into receptor assembly, ligand recognition, and initiation of signaling KW Wucherpfennig, E Gagnon, MJ Call, ES Huseby, ME Call Cold Spring Harbor perspectives in biology 2 (4), a005140, 2010 | 311 | 2010 |
Immunity to oncogenic proteins MA Cheever, ML Disis, H Bernhard, JR Gralow, SL Hand, ES Huseby, ... Immunological reviews 145 (1), 33-59, 1995 | 213 | 1995 |
Crossreactive T cells spotlight the germline rules for αβ T cell-receptor interactions with MHC molecules S Dai, ES Huseby, K Rubtsova, J Scott-Browne, F Crawford, ... Immunity 28 (3), 324-334, 2008 | 195 | 2008 |
Coreceptor scanning by the T cell receptor provides a mechanism for T cell tolerance O Stepanek, AS Prabhakar, C Osswald, CG King, A Bulek, D Naeher, ... Cell 159 (2), 333-345, 2014 | 193 | 2014 |
Fast on-rates allow short dwell time ligands to activate T cells CC Govern, MK Paczosa, AK Chakraborty, ES Huseby Proceedings of the National Academy of Sciences 107 (19), 8724-8729, 2010 | 178 | 2010 |
αβ T cell receptors as predictors of health and disease M Attaf, E Huseby, AK Sewell Cellular & molecular immunology 12 (4), 391-399, 2015 | 163 | 2015 |
Hydrophobic CDR3 residues promote the development of self-reactive T cells BD Stadinski, K Shekhar, I Gómez-Touriño, J Jung, K Sasaki, AK Sewell, ... Nature immunology 17 (8), 946-955, 2016 | 148 | 2016 |
CD8+ T Cell Tolerance to a Tumor-associated Antigen Is Maintained at the Level of Expansion Rather than Effector Function C Ohlen, M Kalos, LE Cheng, AC Shur, DJ Hong, BD Carson, NCT Kokot, ... The Journal of experimental medicine 195 (11), 1407-1418, 2002 | 141 | 2002 |
How the thymus designs antigen-specific and self-tolerant T cell receptor sequences A Košmrlj, AK Jha, ES Huseby, M Kardar, AK Chakraborty Proceedings of the National Academy of Sciences 105 (43), 16671-16676, 2008 | 139 | 2008 |
Antigen affinity and antigen dose exert distinct influences on CD4 T-cell differentiation S Keck, M Schmaler, S Ganter, L Wyss, S Oberle, ES Huseby, D Zehn, ... Proceedings of the National Academy of Sciences 111 (41), 14852-14857, 2014 | 137 | 2014 |
Age-dependent T cell tolerance and autoimmunity to myelin basic protein ES Huseby, B Sather, PG Huseby, J Goverman Immunity 14 (4), 471-481, 2001 | 128 | 2001 |
Relapsing–remitting central nervous system autoimmunity mediated by GFAP-specific CD8 T cells K Sasaki, A Bean, S Shah, E Schutten, PG Huseby, B Peters, ZT Shen, ... The Journal of Immunology 192 (7), 3029-3042, 2014 | 126 | 2014 |
Pathogenic CD8 T cells in multiple sclerosis and its experimental models ES Huseby, PG Huseby, S Shah, R Smith, BD Stadinski Frontiers in immunology 3, 64, 2012 | 126 | 2012 |
Affinity for self antigen selects Treg cells with distinct functional properties L Wyss, BD Stadinski, CG King, S Schallenberg, NI McCarthy, JY Lee, ... Nature immunology 17 (9), 1093-1101, 2016 | 119 | 2016 |
Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide ES Huseby, F Crawford, J White, P Marrack, JW Kappler Nature immunology 7 (11), 1191-1199, 2006 | 114 | 2006 |