| ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells M Kwok, N Davies, A Agathanggelou, E Smith, C Oldreive, E Petermann, ... Blood, The Journal of the American Society of Hematology 127 (5), 582-595, 2016 | 286 | 2016 |
| Finishing the euchromatic sequence of the human genome. Human Genome Sequencing Consortium Nature 431 (7011), 2004 | 234 | 2004 |
| Mutations in SLC29A3, Encoding an Equilibrative Nucleoside Transporter ENT3, Cause a Familial Histiocytosis Syndrome (Faisalabad Histiocytosis) and Familial … NV Morgan, MR Morris, H Cangul, D Gleeson, A Straatman-Iwanowska, ... PLoS genetics 6 (2), e1000833, 2010 | 209 | 2010 |
| BOD1L is required to suppress deleterious resection of stressed replication forks MR Higgs, JJ Reynolds, A Winczura, AN Blackford, V Borel, ES Miller, ... Molecular cell 59 (3), 462-477, 2015 | 202 | 2015 |
| Bayesian variable selection in multinomial probit models to identify molecular signatures of disease stage N Sha, M Vannucci, MG Tadesse, PJ Brown, I Dragoni, N Davies, ... Biometrics 60 (3), 812-819, 2004 | 177 | 2004 |
| The aldo-keto reductase AKR1C3 contributes to 7, 12-dimethylbenz (a) anthracene-3, 4-dihydrodiol mediated oxidative DNA damage in myeloid cells: implications for leukemogenesis J Birtwistle, RE Hayden, FL Khanim, RM Green, C Pearce, NJ Davies, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 662 (1 …, 2009 | 98 | 2009 |
| Synthetic lethality in chronic lymphocytic leukaemia with DNA damage response defects by targeting the ATR pathway M Kwok, N Davies, A Agathanggelou, E Smith, E Petermann, E Yates, ... The Lancet 385, S58, 2015 | 84 | 2015 |
| Combined bezafibrate and medroxyprogesterone acetate: potential novel therapy for acute myeloid leukaemia FL Khanim, RE Hayden, J Birtwistle, A Lodi, S Tiziani, NJ Davies, JP Ride, ... PLoS One 4 (12), e8147, 2009 | 84 | 2009 |
| Human mesenchymal stem cells are recruited to injured liver in a β1-integrin and CD44 dependent manner V Aldridge, A Garg, N Davies, DC Bartlett, J Youster, H Beard, ... Hepatology 56 (3), 1063-1073, 2012 | 82 | 2012 |
| USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status A Agathanggelou, E Smith, NJ Davies, M Kwok, A Zlatanou, CE Oldreive, ... Blood, The Journal of the American Society of Hematology 130 (2), 156-166, 2017 | 77 | 2017 |
| Lack of functional and expression homology between human and mouse aldo-keto reductase 1C enzymes: implications for modelling human cancers P Veliça, NJ Davies, PP Rocha, H Schrewe, JP Ride, CM Bunce Molecular cancer 8, 1-12, 2009 | 74 | 2009 |
| AKR1C isoforms represent a novel cellular target for jasmonates alongside their mitochondrial-mediated effects NJ Davies, RE Hayden, PJ Simpson, J Birtwistle, K Mayer, JP Ride, ... Cancer Research 69 (11), 4769-4775, 2009 | 68 | 2009 |
| Treatment of primary CLL cells with bezafibrate and medroxyprogesterone acetate induces apoptosis and represses the pro-proliferative signal of CD40-ligand, in part through … RE Hayden, G Pratt, NJ Davies, FL Khanim, J Birtwistle, J Delgado, ... Leukemia 23 (2), 292-304, 2009 | 41 | 2009 |
| Selective AKR1C3 inhibitors do not recapitulate the anti-leukaemic activities of the pan-AKR1C inhibitor medroxyprogesterone acetate F Khanim, N Davies, P Veliça, R Hayden, J Ride, C Pararasa, MG Chong, ... British journal of cancer 110 (6), 1506-1516, 2014 | 35 | 2014 |
| Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL M Kwok, C Oldreive, AC Rawstron, A Goel, G Papatzikas, RE Jones, ... Blood, The Journal of the American Society of Hematology 135 (6), 411-428, 2020 | 29 | 2020 |
| TLR9 expression in chronic lymphocytic leukemia identifies a promigratory subpopulation and novel therapeutic target E Kennedy, E Coulter, E Halliwell, N Profitos-Peleja, E Walsby, B Clark, ... Blood, The Journal of the American Society of Hematology 137 (22), 3064-3078, 2021 | 26 | 2021 |
| Targeting the Ataxia Telangiectasia Mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants A Agathanggelou, VJ Weston, T Perry, NJ Davies, A Skowronska, ... haematologica 100 (8), 1076, 2015 | 23 | 2015 |
| Dynamic changes in clonal cytogenetic architecture during progression of chronic lymphocytic leukemia in patients and patient-derived murine xenografts NJ Davies, M Kwok, C Gould, CE Oldreive, J Mao, H Parry, E Smith, ... Oncotarget 8 (27), 44749, 2017 | 18 | 2017 |
| Mitotic control of human papillomavirus genome-containing cells is regulated by the function of the PDZ-binding motif of the E6 oncoprotein EK Marsh, CP Delury, NJ Davies, CJ Weston, MAL Miah, L Banks, ... Oncotarget 8 (12), 19491, 2017 | 18 | 2017 |
| Targeting the p53 pathway in CLL: State of the art and future perspectives M Kwok, A Agathanggelou, N Davies, T Stankovic Cancers 13 (18), 4681, 2021 | 17 | 2021 |
