Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells B Zhang, S Ma, I Rachmin, M He, P Baral, S Choi, WA Gonçalves, ... Nature 577 (7792), 676-681, 2020 | 243 | 2020 |
Wolbachia Enhance Drosophila Stem Cell Proliferation and Target the Germline Stem Cell Niche EM Fast, ME Toomey, K Panaram, D Desjardins, ED Kolaczyk, ... Science 334 (6058), 990-992, 2011 | 206 | 2011 |
A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development H Fu, J Cai, H Clevers, E Fast, S Gray, R Greenberg, MK Jain, Q Ma, ... Journal of Neuroscience 29 (36), 11399-11408, 2009 | 136 | 2009 |
The Gut Commensal Microbiome of Drosophila melanogaster Is Modified by the Endosymbiont Wolbachia RK Simhadri, EM Fast, R Guo, MJ Schultz, N Vaisman, L Ortiz, J Bybee, ... MSphere 2 (5), 10.1128/msphere. 00287-17, 2017 | 110 | 2017 |
Evolutionarily conserved Wolbachia-encoded factors control pattern of stem-cell niche tropism in Drosophila ovaries and favor infection ME Toomey, K Panaram, EM Fast, C Beatty, HM Frydman Proceedings of the National Academy of Sciences 110 (26), 10788-10793, 2013 | 99 | 2013 |
Getting more for your marrow: boosting hematopoietic stem cell numbers with PGE2 EJ Hagedorn, EM Durand, EM Fast, LI Zon Experimental cell research 329 (2), 220-226, 2014 | 76 | 2014 |
Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132 JL Lahvic, M Ammerman, P Li, MC Blair, ER Stillman, EM Fast, ... Proceedings of the National Academy of Sciences 115 (37), 9252-9257, 2018 | 54 | 2018 |
A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo DS Ziegler, J Keating, S Kesari, EM Fast, L Zawel, N Ramakrishna, ... Neuro-oncology 13 (8), 820-829, 2011 | 43 | 2011 |
Lonafarnib (SCH66336) improves the activity of temozolomide and radiation for orthotopic malignant gliomas D Chaponis, JW Barnes, JL Dellagatta, S Kesari, E Fast, C Sauvageot, ... Journal of neuro-oncology 104, 179-189, 2011 | 40 | 2011 |
External signals regulate continuous transcriptional states in hematopoietic stem cells EM Fast, A Sporrij, M Manning, EL Rocha, S Yang, Y Zhou, J Guo, ... Elife 10, e66512, 2021 | 20 | 2021 |
Using zebrafish to study pathways that regulate hematopoietic stem cell self-renewal and migration A Choudhuri, EM Fast, LI Zon Stem Cell Reports 8 (6), 1465-1471, 2017 | 17 | 2017 |
Transplanted organoids empower human preclinical assessment of drug candidate for the clinic AD Westerling-Bui, EM Fast, TW Soare, S Venkatachalan, M DeRan, ... Science Advances 8 (27), eabj5633, 2022 | 15 | 2022 |
Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes R Nasrallah, EM Fast, P Solaimani, K Knezevic, A Eliades, R Patel, ... Blood, The Journal of the American Society of Hematology 128 (15), 1928-1939, 2016 | 7 | 2016 |
A translational kidney organoid system bolsters human relevance of clinical development candidate A Westerling-Bui, TW Soare, S Venkatachalan, M DeRan, EM Fast, ... bioRxiv, 2019.12. 30.891440, 2019 | 4 | 2019 |
PGE2 alters chromatin through H2A.Z-variant enhancer nucleosome modification to promote hematopoietic stem cell fate A Sporrij, A Choudhuri, M Prasad, B Muhire, EM Fast, ME Manning, ... Proceedings of the National Academy of Sciences 120 (19), e2220613120, 2023 | 2 | 2023 |
A short pulse of prostaglandin E2 (PGE2) induces long term chromatin changes in hematopoietic stem cells leading to increased self-renewal and engraftment EM Fast, EM Durand, A Sporrij, L Ojeaburu, R Maher, V Binder, S Yang, ... Blood 126 (23), 246, 2015 | 2 | 2015 |
Niche signals regulate continuous transcriptional states in hematopoietic stem cells EM Fast, A Sporrij, M Manning, EL da Rocha, S Yang, Y Zhou, J Guo, ... bioRxiv, 2021.03. 09.430613, 2021 | 1 | 2021 |
Prostaglandin E2 stimulates CREB-mediated modification of histone variant nucleosomes at enhancers to promote hematopoietic stem cell fate A Sporrij, EM Fast, B Muhire, M Manning, M Kalocsay, RE Kingston, ... Blood 132, 530, 2018 | 1 | 2018 |
INAUGURAL ARTICLE by a Recently Elected Academy Member: PGE2 alters chromatin through H2A. Z-variant enhancer nucleosome modification to promote hematopoietic stem cell fate A Sporrij, A Choudhuri, M Prasad, B Muhire, EM Fast, ME Manning, ... Proceedings of the National Academy of Sciences of the United States of …, 2023 | | 2023 |
Stimulation-responsive enhancers regulate inflammatory gene activation through retention and modification of H2A. Z-variant accessible nucleosomes A Sporrij, M Prasad, B Muhire, EM Fast, ME Manning, A Choudhuri, ... bioRxiv, 2022.09. 12.507565, 2022 | | 2022 |