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Eva M Fast
Eva M Fast
Computational Biologist, Pfizer
在 pfizer.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells
B Zhang, S Ma, I Rachmin, M He, P Baral, S Choi, WA Gonçalves, ...
Nature 577 (7792), 676-681, 2020
2432020
Wolbachia Enhance Drosophila Stem Cell Proliferation and Target the Germline Stem Cell Niche
EM Fast, ME Toomey, K Panaram, D Desjardins, ED Kolaczyk, ...
Science 334 (6058), 990-992, 2011
2062011
A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development
H Fu, J Cai, H Clevers, E Fast, S Gray, R Greenberg, MK Jain, Q Ma, ...
Journal of Neuroscience 29 (36), 11399-11408, 2009
1362009
The Gut Commensal Microbiome of Drosophila melanogaster Is Modified by the Endosymbiont Wolbachia
RK Simhadri, EM Fast, R Guo, MJ Schultz, N Vaisman, L Ortiz, J Bybee, ...
MSphere 2 (5), 10.1128/msphere. 00287-17, 2017
1102017
Evolutionarily conserved Wolbachia-encoded factors control pattern of stem-cell niche tropism in Drosophila ovaries and favor infection
ME Toomey, K Panaram, EM Fast, C Beatty, HM Frydman
Proceedings of the National Academy of Sciences 110 (26), 10788-10793, 2013
992013
Getting more for your marrow: boosting hematopoietic stem cell numbers with PGE2
EJ Hagedorn, EM Durand, EM Fast, LI Zon
Experimental cell research 329 (2), 220-226, 2014
762014
Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132
JL Lahvic, M Ammerman, P Li, MC Blair, ER Stillman, EM Fast, ...
Proceedings of the National Academy of Sciences 115 (37), 9252-9257, 2018
542018
A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo
DS Ziegler, J Keating, S Kesari, EM Fast, L Zawel, N Ramakrishna, ...
Neuro-oncology 13 (8), 820-829, 2011
432011
Lonafarnib (SCH66336) improves the activity of temozolomide and radiation for orthotopic malignant gliomas
D Chaponis, JW Barnes, JL Dellagatta, S Kesari, E Fast, C Sauvageot, ...
Journal of neuro-oncology 104, 179-189, 2011
402011
External signals regulate continuous transcriptional states in hematopoietic stem cells
EM Fast, A Sporrij, M Manning, EL Rocha, S Yang, Y Zhou, J Guo, ...
Elife 10, e66512, 2021
202021
Using zebrafish to study pathways that regulate hematopoietic stem cell self-renewal and migration
A Choudhuri, EM Fast, LI Zon
Stem Cell Reports 8 (6), 1465-1471, 2017
172017
Transplanted organoids empower human preclinical assessment of drug candidate for the clinic
AD Westerling-Bui, EM Fast, TW Soare, S Venkatachalan, M DeRan, ...
Science Advances 8 (27), eabj5633, 2022
152022
Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes
R Nasrallah, EM Fast, P Solaimani, K Knezevic, A Eliades, R Patel, ...
Blood, The Journal of the American Society of Hematology 128 (15), 1928-1939, 2016
72016
A translational kidney organoid system bolsters human relevance of clinical development candidate
A Westerling-Bui, TW Soare, S Venkatachalan, M DeRan, EM Fast, ...
bioRxiv, 2019.12. 30.891440, 2019
42019
PGE2 alters chromatin through H2A.Z-variant enhancer nucleosome modification to promote hematopoietic stem cell fate
A Sporrij, A Choudhuri, M Prasad, B Muhire, EM Fast, ME Manning, ...
Proceedings of the National Academy of Sciences 120 (19), e2220613120, 2023
22023
A short pulse of prostaglandin E2 (PGE2) induces long term chromatin changes in hematopoietic stem cells leading to increased self-renewal and engraftment
EM Fast, EM Durand, A Sporrij, L Ojeaburu, R Maher, V Binder, S Yang, ...
Blood 126 (23), 246, 2015
22015
Niche signals regulate continuous transcriptional states in hematopoietic stem cells
EM Fast, A Sporrij, M Manning, EL da Rocha, S Yang, Y Zhou, J Guo, ...
bioRxiv, 2021.03. 09.430613, 2021
12021
Prostaglandin E2 stimulates CREB-mediated modification of histone variant nucleosomes at enhancers to promote hematopoietic stem cell fate
A Sporrij, EM Fast, B Muhire, M Manning, M Kalocsay, RE Kingston, ...
Blood 132, 530, 2018
12018
INAUGURAL ARTICLE by a Recently Elected Academy Member: PGE2 alters chromatin through H2A. Z-variant enhancer nucleosome modification to promote hematopoietic stem cell fate
A Sporrij, A Choudhuri, M Prasad, B Muhire, EM Fast, ME Manning, ...
Proceedings of the National Academy of Sciences of the United States of …, 2023
2023
Stimulation-responsive enhancers regulate inflammatory gene activation through retention and modification of H2A. Z-variant accessible nucleosomes
A Sporrij, M Prasad, B Muhire, EM Fast, ME Manning, A Choudhuri, ...
bioRxiv, 2022.09. 12.507565, 2022
2022
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