The hammerhead, hairpin and VS ribozymes are catalytically proficient in monovalent cations alone JB Murray, AA Seyhan, NG Walter, JM Burke, WG Scott Chemistry & biology 5 (10), 587-595, 1998 | 537 | 1998 |
Lost in translation: the valley of death across preclinical and clinical divide–identification of problems and overcoming obstacles AA Seyhan Translational Medicine Communications 4 (1), 1-19, 2019 | 478 | 2019 |
Are innovation and new technologies in precision medicine paving a new era in patients centric care? AA Seyhan, C Carini Journal of Translational Medicine 2019 (17), 114, 2019 | 247 | 2019 |
Pancreas-enriched miRNAs are altered in the circulation of subjects with diabetes: a pilot cross-sectional study AA Seyhan, YO Nunez Lopez, H Xie, F Yi, C Mathews, M Pasarica, ... Scientific reports 6 (1), 31479, 2016 | 180 | 2016 |
Altered levels of circulating cytokines and microRNAs in lean and obese individuals with prediabetes and type 2 diabetes YON Lopez, G Garufi, AA Seyhan Molecular biosystems 13 (1), 106-121, 2017 | 148 | 2017 |
RNAi: a potential new class of therapeutic for human genetic disease AA Seyhan Human genetics 130 (5), 583-605, 2011 | 128 | 2011 |
ONC201 and imipridones: Anti-cancer compounds with clinical efficacy VV Prabhu, S Morrow, AR Kawakibi, L Zhou, M Ralff, J Ray, A Jhaveri, ... Neoplasia 22 (12), 725-744, 2020 | 123 | 2020 |
Targeting the integrated stress response in cancer therapy X Tian, S Zhang, L Zhou, AA Seyhan, L Hernandez Borrero, Y Zhang, ... Frontiers in Pharmacology 12, 747837, 2021 | 100 | 2021 |
shRNAs targeting hepatitis C: effects of sequence and structural features, and comparision with siRNA AV Vlassov, B Korba, K Farrar, S Mukerjee, AA Seyhan, H Ilves, ... Oligonucleotides 17 (2), 223-236, 2007 | 77 | 2007 |
Gastric bypass surgery with exercise alters plasma microRNAs that predict improvements in cardiometabolic risk YO Nunez Lopez, PM Coen, BH Goodpaster, AA Seyhan International Journal of Obesity 41 (7), 1121-1130, 2017 | 69 | 2017 |
Role of microRNAs in alcohol-induced multi-organ injury SK Natarajan, JM Pachunka, JL Mott Biomolecules 5 (4), 3309-3338, 2015 | 64 | 2015 |
Predicting and understanding the response to short-term intensive insulin therapy in people with early type 2 diabetes YON Lopez, R Retnakaran, B Zinman, RE Pratley, AA Seyhan Molecular metabolism 20, 63-78, 2019 | 53 | 2019 |
RNA interference from multimeric shRNAs generated by rolling circle transcription AA Seyhan, AV Vlassov, BH Johnston Oligonucleotides 16 (4), 353-363, 2006 | 53 | 2006 |
Elevated and correlated expressions of miR‐24, miR‐30d, miR‐146a, and SFRP‐4 in human abdominal adipose tissue play a role in adiposity and insulin resistance YO Nunez Lopez, G Garufi, M Pasarica, AA Seyhan International Journal of Endocrinology 2018 (1), 7351902, 2018 | 46 | 2018 |
Complete, gene-specific siRNA libraries: production and expression in mammalian cells AA Seyhan, AV Vlassov, H Ilves, L Egry, RL Kaspar, SA Kazakov, ... Rna 11 (5), 837-846, 2005 | 46 | 2005 |
A genome-wide RNAi screen identifies novel targets of neratinib resistance leading to identification of potential drug resistant genetic markers AA Seyhan, U Varadarajan, S Choe, W Liu, TE Ryan Molecular bioSystems 8 (5), 1553-1570, 2012 | 45 | 2012 |
Mouse ferritin H subunit gene. Functional analysis of the promoter and identification of an upstream regulatory element active in erythroid cells. C Beaumont, A Seyhan, AK Yachou, B Grandchamp, R Jones Journal of Biological Chemistry 269 (32), 20281-20288, 1994 | 45 | 1994 |
The biomarkers of lupus disease study: a bold approach may mitigate interference of background immunosuppressants in clinical trials SS Joan T. Merrill, Fred Immermann, Maryann Whitley, Tianhui Zhou, Andrew ... Arthritis Rheumatol 69 (6), 1257-1266, 2017 | 44 | 2017 |
microRNAs with different functions and roles in disease development and as potential biomarkers of diabetes: progress and challenges AA Seyhan Molecular BioSystems 11 (5), 1217-1234, 2015 | 41 | 2015 |
Mg2+-independent hairpin ribozyme catalysis in hydrated RNA films. AA Seyhan, JM Burke Rna 6 (2), 189-198, 2000 | 40 | 2000 |