| Epigallocatechin‐3‐gallate, a DYRK1A inhibitor, rescues cognitive deficits in D own syndrome mouse models and in humans R De la Torre, S De Sola, M Pons, A Duchon, MM de Lagran, M Farré, ... Molecular nutrition & food research 58 (2), 278-288, 2014 | 352 | 2014 |
| Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 … R de la Torre, S de Sola, G Hernandez, M Farré, J Pujol, J Rodriguez, ... The Lancet Neurology 15 (8), 801-810, 2016 | 305 | 2016 |
| Cystathionine β synthase deficiency promotes oxidative stress, fibrosis, and steatosis in mice liver K Robert, J Nehmé, E Bourdon, G Pivert, B Friguet, C Delcayre, ... Gastroenterology 128 (5), 1405-1415, 2005 | 234 | 2005 |
| Expression of the cystathionine β synthase (CBS) gene during mouse development and immunolocalization in adult brain K Robert, F Vialard, E Thiery, K Toyama, PM Sinet, N Janel, J London Journal of Histochemistry & Cytochemistry 51 (3), 363-371, 2003 | 183 | 2003 |
| Connexin30 deficiency causes instrastrial fluid–blood barrier disruption within the cochlear stria vascularis M Cohen-Salmon, B Regnault, N Cayet, D Caille, K Demuth, JP Hardelin, ... Proceedings of the National Academy of Sciences 104 (15), 6229-6234, 2007 | 176 | 2007 |
| Hyperhomocysteinemia due to cystathionine beta synthase deficiency induces dysregulation of genes involved in hepatic lipid homeostasis in mice J Hamelet, K Demuth, JL Paul, JM Delabar, N Janel Journal of hepatology 46 (1), 151-159, 2007 | 139 | 2007 |
| Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage B Souchet, F Guedj, I Sahún, A Duchon, F Daubigney, A Badel, ... Neurobiology of disease 69, 65-75, 2014 | 124 | 2014 |
| Prefrontal deficits in a murine model overexpressing the down syndrome candidate gene dyrk1a A Thomazeau, O Lassalle, J Iafrati, B Souchet, F Guedj, N Janel, P Chavis, ... Journal of Neuroscience 34 (4), 1138-1147, 2014 | 104 | 2014 |
| Islet endothelial activation and oxidative stress gene expression is reduced by IL-1Ra treatment in the type 2 diabetic GK rat G Lacraz, MH Giroix, N Kassis, J Coulaud, A Galinier, C Noll, M Cornut, ... PloS one 4 (9), e6963, 2009 | 88 | 2009 |
| Type 2 diabetes mellitus and Alzheimer’s disease: shared molecular mechanisms and potential common therapeutic targets R Hamzé, E Delangre, S Tolu, M Moreau, N Janel, D Bailbé, J Movassat International journal of molecular sciences 23 (23), 15287, 2022 | 86 | 2022 |
| Regulation of extracellular signal-regulated kinase by homocysteine in hippocampus K Robert, C Pages, A Ledru, J Delabar, J Caboche, N Janel Neuroscience 133 (4), 925-935, 2005 | 85 | 2005 |
| Altered gene expression in liver from a murine model of hyperhomocysteinemia K Robert, JF Chassé, D Santiard-Baron, C Vayssettes, A Chabli, J Aupetit, ... Journal of Biological Chemistry 278 (34), 31504-31511, 2003 | 85 | 2003 |
| Development of DANDYs, new 3, 5-diaryl-7-azaindoles demonstrating potent DYRK1A kinase inhibitory activity S Gourdain, J Dairou, C Denhez, LC Bui, F Rodrigues-Lima, N Janel, ... Journal of Medicinal Chemistry 56 (23), 9569-9585, 2013 | 76 | 2013 |
| Pharmacological correction of excitation/inhibition imbalance in Down syndrome mouse models B Souchet, F Guedj, Z Penke-Verdier, F Daubigney, A Duchon, Y Herault, ... Frontiers in behavioral neuroscience 9, 267, 2015 | 69 | 2015 |
| Effects of red wine polyphenolic compounds on paraoxonase-1 and lectin-like oxidized low-density lipoprotein receptor-1 in hyperhomocysteinemic mice C Noll, J Hamelet, E Matulewicz, JL Paul, JM Delabar, N Janel The Journal of nutritional biochemistry 20 (8), 586-596, 2009 | 66 | 2009 |
| DYRK1A, a novel determinant of the methionine-homocysteine cycle in different mouse models overexpressing this Down-syndrome-associated kinase C Noll, C Planque, C Ripoll, F Guedj, A Diez, V Ducros, N Belin, ... PLoS One 4 (10), e7540, 2009 | 63 | 2009 |
| Myocardial fibrosis and TGFB expression in hyperhomocysteinemic rats L Raaf, C Noll, MEH Cherifi, JL Samuel, C Delcayre, JM Delabar, ... Molecular and cellular biochemistry 347, 63-70, 2011 | 62 | 2011 |
| Identification of the xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 as a new target of cisplatin in breast cancer cells: molecular and cellular mechanisms of … N Ragunathan, J Dairou, B Pluvinage, M Martins, E Petit, N Janel, ... Molecular pharmacology 73 (6), 1761-1768, 2008 | 62 | 2008 |
| Dyrk1A induces pancreatic β cell mass expansion and improves glucose tolerance L Rachdi, D Kariyawasam, V Aïello, Y Herault, N Janel, JM Delabar, ... Cell Cycle 13 (14), 2221-2229, 2014 | 58 | 2014 |
| Metabolic diseases and Down syndrome: how are they linked together? M Moreau, S Benhaddou, R Dard, S Tolu, R Hamzé, F Vialard, ... Biomedicines 9 (2), 221, 2021 | 52 | 2021 |
