| Exosomes: a common pathway for a specialized function G Van Niel, I Porto-Carreiro, S Simoes, G Raposo Journal of biochemistry 140 (1), 13-21, 2006 | 1099 | 2006 |
| The tetraspanin CD63 regulates ESCRT-independent and-dependent endosomal sorting during melanogenesis G Van Niel, S Charrin, S Simoes, M Romao, L Rochin, P Saftig, MS Marks, ... Developmental cell 21 (4), 708-721, 2011 | 980 | 2011 |
| Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons JW Wu, M Herman, L Liu, S Simoes, CM Acker, H Figueroa, JI Steinberg, ... Journal of Biological Chemistry 288 (3), 1856-1870, 2013 | 579 | 2013 |
| Pharmacological chaperones stabilize retromer to limit APP processing VJ Mecozzi, DE Berman, S Simoes, C Vetanovetz, MR Awal, VM Patel, ... Nature chemical biology 10 (6), 443-449, 2014 | 246 | 2014 |
| Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system E Morel, Z Chamoun, ZM Lasiecka, RB Chan, RL Williamson, ... Nature communications 4 (1), 2250, 2013 | 233 | 2013 |
| Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures AM Miranda, ZM Lasiecka, Y Xu, J Neufeld, S Shahriar, S Simoes, ... Nature communications 9 (1), 291, 2018 | 207 | 2018 |
| Mouse neuroblastoma cells release prion infectivity associated with exosomal vesicles S Alais, S Simoes, D Baas, S Lehmann, G Raposo, JL Darlix, P Leblanc Biology of the Cell 100 (10), 603-618, 2008 | 183 | 2008 |
| Endosomal Traffic Jams Represent a Pathogenic Hub and Therapeutic Target in Alzheimer’s Disease SA Small, SabrinaSimoes-Spassov, RichardMayeux, GA Petsko Trends in Neurosciences 40 (10), 592-602, 2017 | 135 | 2017 |
| Cerebrovascular disease promotes tau pathology in Alzheimer’s disease KK Laing, S Simoes, GP Baena-Caldas, PJ Lao, M Kothiya, KC Igwe, ... Brain communications 2 (2), fcaa132, 2020 | 63 | 2020 |
| Efficient inhibition of infectious prions multiplication and release by targeting the exosomal pathway D Vilette, K Laulagnier, A Huor, S Alais, S Simoes, M Provansal, ... Cellular and Molecular Life Sciences 72, 4409-4427, 2015 | 60 | 2015 |
| ESCRT‐I function is required for Tyrp1 transport from early endosomes to the melanosome limiting membrane ST Truschel, S Simoes, SR Gangi Setty, DC Harper, D Tenza, PC Thomas, ... Traffic 10 (9), 1318-1336, 2009 | 52 | 2009 |
| Tau and other proteins found in Alzheimer’s disease spinal fluid are linked to retromer-mediated endosomal traffic in mice and humans S Simoes, JL Neufeld, G Triana-Baltzer, S Moughadam, EI Chen, ... Science translational medicine 12 (571), eaba6334, 2020 | 43 | 2020 |
| Alzheimer's vulnerable brain region relies on a distinct retromer core dedicated to endosomal recycling S Simoes, J Guo, L Buitrago, YH Qureshi, X Feng, M Kothiya, E Cortes, ... Cell reports 37 (13), 2021 | 41 | 2021 |
| The ocular albinism type 1 (OA1) GPCR is ubiquitinated and its traffic requires endosomal sorting complex responsible for transport (ESCRT) function F Giordano, S Simoes, G Raposo Proceedings of the National Academy of Sciences 108 (29), 11906-11911, 2011 | 39 | 2011 |
| The neuronal retromer can regulate both neuronal and microglial phenotypes of Alzheimer's disease YH Qureshi, DE Berman, SE Marsh, RL Klein, VM Patel, S Simoes, ... Cell reports 38 (3), 2022 | 19 | 2022 |
| Point Du Jour, KS; McCabe, BD; et al. Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system E Morel, Z Chamoun, ZM Lasiecka, RB Chan, RL Williamson, ... Nat. Commun 4, 2250, 2013 | 13 | 2013 |
| Endosomal trafficking is required for glycosylation and normal maturation of the Alzheimer’s-associated protein sorLA SK Christensen, Y Narimatsu, S Simoes, CK Goth, CB Vægter, SA Small, ... BioRxiv, 2020.07. 12.199885, 2020 | 8 | 2020 |
| Retromer repletion with AAV9-VPS35 restores endosomal function in the mouse hippocampus YH Qureshi, DE Berman, RL Klein, VM Patel, S Simoes, S Kannan, R Cox, ... bioRxiv, 618496, 2019 | 7 | 2019 |
| PI3P regulates sorting and processing of amyloid precursor protein through the endosomal system E Morel, Z Chamoun, ZM Lasiecka, RB Chan, RL Williamson, ... Nature communications 4, 2250, 2013 | 6 | 2013 |
| Endo-lysosomal dysfunction in neurodegenerative diseases: Opinion on current progress and future direction in the use of exosomes as biomarkers M Herman, GW Randall, JL Spiegel, DJ Maldonado, S Simoes Philosophical Transactions of the Royal Society B 379 (1899), 20220387, 2024 | 3 | 2024 |
