| Crystal structures and catalytic mechanism of cytochrome P450 StaP that produces the indolocarbazole skeleton M Makino, H Sugimoto, Y Shiro, S Asamizu, H Onaka, S Nagano Proceedings of the National Academy of Sciences 104 (28), 11591-11596, 2007 | 134 | 2007 |
| De novo synthesis of a sunscreen compound in vertebrates AR Osborn, KH Almabruk, G Holzwarth, S Asamizu, J LaDu, KM Kean, ... Elife 4, e05919, 2015 | 94 | 2015 |
| 5-Alkyl-1, 2, 3, 4-tetrahydroquinolines, new membrane-interacting lipophilic metabolites produced by combined culture of Streptomyces nigrescens and Tsukamurella pulmonis R Sugiyama, S Nishimura, T Ozaki, S Asamizu, H Onaka, H Kakeya Organic letters 17 (8), 1918-1921, 2015 | 81 | 2015 |
| Theoretical and experimental studies of the conversion of chromopyrrolic acid to an antitumor derivative by cytochrome P450 StaP: the catalytic role of water molecules Y Wang, H Chen, M Makino, Y Shiro, S Nagano, S Asamizu, H Onaka, ... Journal of the American Chemical Society 131 (19), 6748-6762, 2009 | 80 | 2009 |
| Dissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivo T Ozaki, K Yamashita, Y Goto, M Shimomura, S Hayashi, S Asamizu, ... Nature communications 8 (1), 14207, 2017 | 69 | 2017 |
| Arcyriaflavin E, a new cytotoxic indolocarbazole alkaloid isolated by combined-culture of mycolic acid-containing bacteria and Streptomyces cinnamoneus NBRC 13823 S Hoshino, L Zhang, T Awakawa, T Wakimoto, H Onaka, I Abe The Journal of Antibiotics 68 (5), 342-344, 2015 | 65 | 2015 |
| Crystal structure of VioE, a key player in the construction of the molecular skeleton of violacein S Hirano, S Asamizu, H Onaka, Y Shiro, S Nagano Journal of Biological Chemistry 283 (10), 6459-6466, 2008 | 61 | 2008 |
| Genome mining reveals a minimum gene set for the biosynthesis of 32-membered macrocyclic thiopeptides lactazoles S Hayashi, T Ozaki, S Asamizu, H Ikeda, S Ōmura, N Oku, Y Igarashi, ... Chemistry & biology 21 (5), 679-688, 2014 | 60 | 2014 |
| Discovery and total synthesis of streptoaminals: antimicrobial [5, 5]‐spirohemiaminals from the combined‐culture of Streptomyces nigrescens and Tsukamurella pulmonis R Sugiyama, S Nishimura, T Ozaki, S Asamizu, H Onaka, H Kakeya Angewandte Chemie 128 (35), 10434-10438, 2016 | 50 | 2016 |
| Direct formation of chromopyrrolic acid from indole-3-pyruvic acid by StaD, a novel hemoprotein in indolocarbazole biosynthesis S Asamizu, Y Kato, Y Igarashi, T Furumai, H Onaka Tetrahedron letters 47 (4), 473-475, 2006 | 50 | 2006 |
| Mycolic acid containing bacterium stimulates tandem cyclization of polyene macrolactam in a lake sediment derived rare actinomycete S Hoshino, M Okada, T Awakawa, S Asamizu, H Onaka, I Abe Organic letters 19 (18), 4992-4995, 2017 | 49 | 2017 |
| Minimal lactazole scaffold for in vitro thiopeptide bioengineering AA Vinogradov, M Shimomura, Y Goto, T Ozaki, S Asamizu, Y Sugai, ... Nature communications 11 (1), 2272, 2020 | 47 | 2020 |
| Cytochrome P450 Homolog Is Responsible for C–N Bond Formation between Aglycone and Deoxysugar in the Staurosporine Biosynthesis of Streptomyces sp. TP … H Onaka, S Asamizu, Y Igarashi, R Yoshida, T Furumai Bioscience, biotechnology, and biochemistry 69 (9), 1753-1759, 2005 | 47 | 2005 |
| Acyltransferase that catalyses the condensation of polyketide and peptide moieties of goadvionin hybrid lipopeptides R Kozakai, T Ono, S Hoshino, H Takahashi, Y Katsuyama, Y Sugai, ... Nature chemistry 12 (9), 869-877, 2020 | 46 | 2020 |
| Insights into the biosynthesis of dehydroalanines in goadsporin T Ozaki, Y Kurokawa, S Hayashi, N Oku, S Asamizu, Y Igarashi, H Onaka ChemBioChem 17 (3), 218-223, 2016 | 45 | 2016 |
| Evolutionary divergence of sedoheptulose 7-phosphate cyclases leads to several distinct cyclic products S Asamizu, P Xie, CJ Brumsted, PM Flatt, T Mahmud Journal of the American Chemical Society 134 (29), 12219-12229, 2012 | 44 | 2012 |
| Killing of mycolic acid-containing bacteria aborted induction of antibiotic production by Streptomyces in combined-culture S Asamizu, T Ozaki, K Teramoto, K Satoh, H Onaka PloS one 10 (11), e0142372, 2015 | 40 | 2015 |
| VioE, a prodeoxyviolacein synthase involved in violacein biosynthesis, is responsible for intramolecular indole rearrangement S Asamizu, Y Kato, Y Igarashi, H Onaka Tetrahedron letters 48 (16), 2923-2926, 2007 | 36 | 2007 |
| Umezawamides, new bioactive polycyclic tetramate macrolactams isolated from a combined-culture of Umezawaea sp. and mycolic acid-containing bacterium S Hoshino, CP Wong, M Ozeki, H Zhang, F Hayashi, T Awakawa, ... The Journal of antibiotics 71 (7), 653-657, 2018 | 35 | 2018 |
| Pseudoglycosyltransferase catalyzes nonglycosidic C–N coupling in validamycin A biosynthesis S Asamizu, J Yang, KH Almabruk, T Mahmud Journal of the American Chemical Society 133 (31), 12124-12135, 2011 | 35 | 2011 |
Hiroyasu OnakaThe University of Tokyo在 mail.ecc.u-tokyo.ac.jp 的电子邮件经过验证
