Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network MJ McConnell, JV Moran, A Abyzov, S Akbarian, T Bae, I Cortes-Ciriano, ... Science 356 (6336), eaal1641, 2017 | 246 | 2017 |
The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing RE Rodin, Y Dou, M Kwon, MA Sherman, AM D’Gama, RN Doan, ... Nature neuroscience 24 (2), 176-185, 2021 | 87 | 2021 |
Landmarks of human embryonic development inscribed in somatic mutations S Bizzotto, Y Dou, J Ganz, RN Doan, M Kwon, CL Bohrson, SN Kim, ... Science 371 (6535), 1249-1253, 2021 | 79 | 2021 |
Genetic correlates of phenotypic heterogeneity in autism V Warrier, X Zhang, P Reed, A Havdahl, TM Moore, F Cliquet, CS Leblond, ... Nature Genetics 54 (9), 1293-1304, 2022 | 78 | 2022 |
Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons DA Reid, PJ Reed, JCM Schlachetzki, II Nitulescu, G Chou, EC Tsui, ... Science 372 (6537), 91-94, 2021 | 77 | 2021 |
Suppressed accumulation of cerebral amyloid β peptides in aged transgenic Alzheimer’s disease mice by transplantation with wild-type or prostaglandin E2 receptor subtype 2-null … CD Keene, RC Chang, AH Lopez-Yglesias, BR Shalloway, I Sokal, X Li, ... The American journal of pathology 177 (1), 346-354, 2010 | 68 | 2010 |
Comprehensive identification of somatic nucleotide variants in human brain tissue Y Wang, T Bae, J Thorpe, MA Sherman, AG Jones, S Cho, K Daily, Y Dou, ... Genome biology 22, 1-32, 2021 | 35 | 2021 |
Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability T Bae, L Fasching, Y Wang, JH Shin, M Suvakov, Y Jang, S Norton, ... Science 377 (6605), 511-517, 2022 | 33 | 2022 |
Somatic mosaicism reveals clonal distributions of neocortical development MW Breuss, X Yang, JCM Schlachetzki, D Antaki, AJ Lana, X Xu, ... Nature 604 (7907), 689-696, 2022 | 27 | 2022 |
Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia X Zhu, B Zhou, R Pattni, K Gleason, C Tan, A Kalinowski, S Sloan, ... Nature neuroscience 24 (2), 186-196, 2021 | 22 | 2021 |
Control-independent mosaic single nucleotide variant detection with DeepMosaic X Yang, X Xu, MW Breuss, D Antaki, LL Ball, C Chung, J Shen, C Li, ... Nature biotechnology 41 (6), 870-877, 2023 | 13 | 2023 |
Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission S Stern, L Zhang, M Wang, R Wright, I Rosh, Y Hussein, T Stern, ... Molecular Psychiatry, 1-15, 2024 | 8 | 2024 |
EU-AIMS LEAP, iPSYCH-Autism Working Group V Warrier, X Zhang, P Reed, A Havdahl, TM Moore, F Cliquet, CS Leblond, ... Spectrum 10K and APEX Consortium, Rowitch, DH, Hurles, ME, Geschwind, DH …, 2020 | 5 | 2020 |
Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions EA Maury, MA Sherman, G Genovese, TG Gilgenast, T Kamath, SJ Burris, ... Cell Genomics 3 (8), 2023 | 4 | 2023 |
Enrichment of somatic mutations in schizophrenia brain targets prenatally active transcription factor bindings sites EA Maury, A Jones, V Seplyarskiy, C Rosenbluh, T Bae, Y Wang, ... bioRxiv, 2022.02. 23.481681, 2022 | 4 | 2022 |
DeepMosaic: Control-independent mosaic single nucleotide variant detection using deep convolutional neural networks X Yang, X Xu, MW Breuss, D Antaki, LL Ball, C Chung, C Li, RD George, ... bioRxiv, 2020.11. 14.382473, 2020 | 4 | 2020 |
Mapping the Complex Genetic Landscape of Human Neurons C Sun, K Kathuria, SB Emery, BJ Kim, IE Burbulis, JH Shin, BSM Network, ... bioRxiv, 2023 | 3 | 2023 |
Author Correction: The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing RE Rodin, Y Dou, M Kwon, MA Sherman, AM D’Gama, RN Doan, ... Nature neuroscience 24 (4), 611-611, 2021 | 2 | 2021 |
Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures S Podvin, J Jones, A Kang, R Goodman, P Reed, CB Lietz, J Then, ... Molecular Psychiatry, 1-10, 2024 | 1 | 2024 |
Single-cell whole genome amplification and sequencing to study neuronal mosaicism and diversity PJ Reed, M Wang, JA Erwin, ACM Paquola, FH Gage Genomic Mosaicism in Neurons and Other Cell Types, 253-268, 2017 | 1 | 2017 |