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Patrick J. Reed
Patrick J. Reed
Senior Scientist
在 ionisph.com 的电子邮件经过验证
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引用次数
引用次数
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Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network
MJ McConnell, JV Moran, A Abyzov, S Akbarian, T Bae, I Cortes-Ciriano, ...
Science 356 (6336), eaal1641, 2017
2462017
The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing
RE Rodin, Y Dou, M Kwon, MA Sherman, AM D’Gama, RN Doan, ...
Nature neuroscience 24 (2), 176-185, 2021
872021
Landmarks of human embryonic development inscribed in somatic mutations
S Bizzotto, Y Dou, J Ganz, RN Doan, M Kwon, CL Bohrson, SN Kim, ...
Science 371 (6535), 1249-1253, 2021
792021
Genetic correlates of phenotypic heterogeneity in autism
V Warrier, X Zhang, P Reed, A Havdahl, TM Moore, F Cliquet, CS Leblond, ...
Nature Genetics 54 (9), 1293-1304, 2022
782022
Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons
DA Reid, PJ Reed, JCM Schlachetzki, II Nitulescu, G Chou, EC Tsui, ...
Science 372 (6537), 91-94, 2021
772021
Suppressed accumulation of cerebral amyloid β peptides in aged transgenic Alzheimer’s disease mice by transplantation with wild-type or prostaglandin E2 receptor subtype 2-null …
CD Keene, RC Chang, AH Lopez-Yglesias, BR Shalloway, I Sokal, X Li, ...
The American journal of pathology 177 (1), 346-354, 2010
682010
Comprehensive identification of somatic nucleotide variants in human brain tissue
Y Wang, T Bae, J Thorpe, MA Sherman, AG Jones, S Cho, K Daily, Y Dou, ...
Genome biology 22, 1-32, 2021
352021
Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability
T Bae, L Fasching, Y Wang, JH Shin, M Suvakov, Y Jang, S Norton, ...
Science 377 (6605), 511-517, 2022
332022
Somatic mosaicism reveals clonal distributions of neocortical development
MW Breuss, X Yang, JCM Schlachetzki, D Antaki, AJ Lana, X Xu, ...
Nature 604 (7907), 689-696, 2022
272022
Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia
X Zhu, B Zhou, R Pattni, K Gleason, C Tan, A Kalinowski, S Sloan, ...
Nature neuroscience 24 (2), 186-196, 2021
222021
Control-independent mosaic single nucleotide variant detection with DeepMosaic
X Yang, X Xu, MW Breuss, D Antaki, LL Ball, C Chung, J Shen, C Li, ...
Nature biotechnology 41 (6), 870-877, 2023
132023
Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission
S Stern, L Zhang, M Wang, R Wright, I Rosh, Y Hussein, T Stern, ...
Molecular Psychiatry, 1-15, 2024
82024
EU-AIMS LEAP, iPSYCH-Autism Working Group
V Warrier, X Zhang, P Reed, A Havdahl, TM Moore, F Cliquet, CS Leblond, ...
Spectrum 10K and APEX Consortium, Rowitch, DH, Hurles, ME, Geschwind, DH …, 2020
52020
Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions
EA Maury, MA Sherman, G Genovese, TG Gilgenast, T Kamath, SJ Burris, ...
Cell Genomics 3 (8), 2023
42023
Enrichment of somatic mutations in schizophrenia brain targets prenatally active transcription factor bindings sites
EA Maury, A Jones, V Seplyarskiy, C Rosenbluh, T Bae, Y Wang, ...
bioRxiv, 2022.02. 23.481681, 2022
42022
DeepMosaic: Control-independent mosaic single nucleotide variant detection using deep convolutional neural networks
X Yang, X Xu, MW Breuss, D Antaki, LL Ball, C Chung, C Li, RD George, ...
bioRxiv, 2020.11. 14.382473, 2020
42020
Mapping the Complex Genetic Landscape of Human Neurons
C Sun, K Kathuria, SB Emery, BJ Kim, IE Burbulis, JH Shin, BSM Network, ...
bioRxiv, 2023
32023
Author Correction: The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing
RE Rodin, Y Dou, M Kwon, MA Sherman, AM D’Gama, RN Doan, ...
Nature neuroscience 24 (4), 611-611, 2021
22021
Human iN neuronal model of schizophrenia displays dysregulation of chromogranin B and related neuropeptide transmitter signatures
S Podvin, J Jones, A Kang, R Goodman, P Reed, CB Lietz, J Then, ...
Molecular Psychiatry, 1-10, 2024
12024
Single-cell whole genome amplification and sequencing to study neuronal mosaicism and diversity
PJ Reed, M Wang, JA Erwin, ACM Paquola, FH Gage
Genomic Mosaicism in Neurons and Other Cell Types, 253-268, 2017
12017
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