| Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t (8; 21) leukemia in … GB Zhou, H Kang, L Wang, L Gao, P Liu, J Xie, FX Zhang, XQ Weng, ... Blood 109 (8), 3441-3450, 2007 | 285 | 2007 |
| Long-term, efficient inhibition of microRNA function in mice using rAAV vectors J Xie, SL Ameres, R Friedline, JH Hung, Y Zhang, Q Xie, L Zhong, Q Su, ... Nature methods 9 (4), 403-409, 2012 | 233 | 2012 |
| MicroRNA-regulated, systemically delivered rAAV9: a step closer to CNS-restricted transgene expression J Xie, Q Xie, H Zhang, SL Ameres, JH Hung, Q Su, R He, X Mu, ... Molecular therapy 19 (3), 526-535, 2011 | 199 | 2011 |
| Novel AAV's and Uses Thereof G Gao, TR Flotte, J Xie WO Patent WO2010138263 A2, 2010 | 145* | 2010 |
| Short DNA hairpins compromise recombinant adeno-associated virus genome homogeneity J Xie, Q Mao, PWL Tai, R He, J Ai, Q Su, Y Zhu, H Ma, J Li, S Gong, ... Molecular Therapy 25 (6), 1363-1374, 2017 | 117 | 2017 |
| A single intravenous rAAV injection as late as P20 achieves efficacious and sustained CNS Gene therapy in Canavan mice SS Ahmed, H Li, C Cao, EM Sikoglu, AR Denninger, Q Su, S Eaton, ... Molecular therapy 21 (12), 2136-2147, 2013 | 97 | 2013 |
| AAV's and uses thereof G Gao, T Flotte, J Xie US Patent 9,284,357, 2016 | 89 | 2016 |
| AAV-based Treatment of Cholesterol-Related Disorders G Gao, PD Zamore, J Xie US Patent App. PCT/US2011/033,628, 2011 | 87* | 2011 |
| Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis YS Yang, J Xie, D Wang, JM Kim, PWL Tai, E Gravallese, G Gao, JH Shim Nature communications 10 (1), 2958, 2019 | 81 | 2019 |
| Recombinant adeno‐associated virus–mediated inhibition of microRNA‐21 protects mice against the lethal schistosome infection by repressing both IL‐13 and transforming growth … X He, J Xie, D Zhang, Q Su, X Sai, R Bai, C Chen, X Luo, G Gao, W Pan Hepatology 61 (6), 2008-2017, 2015 | 80 | 2015 |
| Multicistronic Expression Constructs G Gao, J XIE US Patent App. PCT/US2011/033,596, 2011 | 77* | 2011 |
| Adeno-associated virus genome population sequencing achieves full vector genome resolution and reveals human-vector chimeras PWL Tai, J Xie, K Fong, M Seetin, C Heiner, Q Su, M Weiand, D Wilmot, ... Molecular Therapy Methods & Clinical Development 9, 130-141, 2018 | 74 | 2018 |
| Adenovirus–adeno-associated virus hybrid for large-scale recombinant adeno-associated virus production H Zhang, J Xie, Q Xie, JM Wilson, G Gao Human gene therapy 20 (9), 922-929, 2009 | 60 | 2009 |
| Recombinant adeno-associated virus integration sites in murine liver after ornithine transcarbamylase gene correction L Zhong, N Malani, M Li, T Brady, J Xie, P Bell, S Li, H Jones, JM Wilson, ... Human gene therapy 24 (5), 520-525, 2013 | 49 | 2013 |
| Adeno-associated virus-mediated microRNA delivery and therapeutics J Xie, DR Burt, G Gao Seminars in liver disease 35 (01), 081-088, 2015 | 46 | 2015 |
| Central amygdala GluA1 facilitates associative learning of opioid reward YQ Cai, W Wang, YY Hou, Z Zhang, J Xie, ZZ Pan Journal of Neuroscience 33 (4), 1577-1588, 2013 | 44 | 2013 |
| Bortezomib interferes with C-KIT processing and transforms the t (8; 21)-generated fusion proteins into tumor-suppressing fragments in leukemia cells HT Fang, B Zhang, XF Pan, L Gao, T Zhen, HX Zhao, L Ma, J Xie, Z Liu, ... Proceedings of the National Academy of Sciences 109 (7), 2521-2526, 2012 | 39 | 2012 |
| Down-regulation of microRNA-203-3p initiates type 2 pathology during schistosome infection via elevation of interleukin-33 X He, J Xie, Y Wang, X Fan, Q Su, Y Sun, N Lei, D Zhang, G Gao, W Pan PLoS Pathogens 14 (3), e1006957, 2018 | 34 | 2018 |
| Conditional, inducible gene silencing in dopamine neurons reveals a sex-specific role for Rit2 GTPase in acute cocaine response and striatal function CG Sweeney, PJ Kearney, RR Fagan, LA Smith, NC Bolden, ... Neuropsychopharmacology 45 (2), 384-393, 2020 | 33 | 2020 |
| AAV-based treatment of cholesterol-related disorders G Gao, PD Zamore, J Xie US Patent 10,202,600, 2019 | 33 | 2019 |
Chengjian Charles Li, Ph.D.Fornax Biotech在 fornaxbio.com 的电子邮件经过验证
Chengjian Charles Li, Ph.D.Fornax Biotech在 fornaxbio.com 的电子邮件经过验证