Empagliflozin ameliorates obesity-related cardiac dysfunction by regulating Sestrin2-mediated AMPK-mTOR signaling and redox homeostasis in high-fat diet–induced obese mice X Sun, F Han, Q Lu, X Li, D Ren, J Zhang, Y Han, YK Xiang, J Li Diabetes 69 (6), 1292-1305, 2020 | 146 | 2020 |
AMPK: A therapeutic target of heart failure—not only metabolism regulation X Li, J Liu, Q Lu, D Ren, X Sun, T Rousselle, Y Tan, J Li Bioscience reports 39 (1), BSR20181767, 2019 | 99 | 2019 |
SIRT1 agonism modulates cardiac NLRP3 inflammasome through pyruvate dehydrogenase during ischemia and reperfusion Y Han, W Sun, D Ren, J Zhang, Z He, J Fedorova, X Sun, F Han, J Li Redox biology 34, 101538, 2020 | 96 | 2020 |
Empagliflozin attenuates ischemia and reperfusion injury through LKB1/AMPK signaling pathway Q Lu, J Liu, X Li, X Sun, J Zhang, D Ren, N Tong, J Li Molecular and cellular endocrinology 501, 110642, 2020 | 92 | 2020 |
AMPK: a balancer of the renin–angiotensin system J Liu, X Li, Q Lu, D Ren, X Sun, T Rousselle, J Li, J Leng Bioscience reports 39 (9), BSR20181994, 2019 | 73 | 2019 |
Protective efficacy of a Toxoplasma gondii rhoptry protein 13 plasmid DNA vaccine in mice PY Wang, ZG Yuan, E Petersen, J Li, XX Zhang, XZ Li, HX Li, ZC Lv, ... Clinical and Vaccine Immunology 19 (12), 1916-1920, 2012 | 59 | 2012 |
AMPK is associated with the beneficial effects of antidiabetic agents on cardiovascular diseases Q Lu, X Li, J Liu, X Sun, T Rousselle, D Ren, N Tong, J Li Bioscience reports 39 (2), BSR20181995, 2019 | 57 | 2019 |
Alterations in mitochondrial dynamics with age‐related Sirtuin1/Sirtuin3 deficiency impair cardiomyocyte contractility J Zhang, Z He, J Fedorova, C Logan, L Bates, K Davitt, V Le, J Murphy, ... Aging cell 20 (7), e13419, 2021 | 55 | 2021 |
Potato spindle tuber viroid modulates its replication through a direct interaction with a splicing regulator J Jiang, HN Smith, D Ren, SD Dissanayaka Mudiyanselage, AL Dawe, ... Journal of Virology 92 (20), 10.1128/jvi. 01004-18, 2018 | 51 | 2018 |
Vaccination with a DNA vaccine coding for perforin-like protein 1 and MIC6 induces significant protective immunity against Toxoplasma gondii HK Yan, ZG Yuan, HQ Song, E Petersen, Y Zhou, D Ren, DH Zhou, HX Li, ... Clinical and Vaccine Immunology 19 (5), 684-689, 2012 | 47 | 2012 |
SIRT1/SIRT3 modulates redox homeostasis during ischemia/reperfusion in the aging heart J Zhang, D Ren, J Fedorova, Z He, J Li Antioxidants 9 (9), 858, 2020 | 40 | 2020 |
Evaluation of protective effect of pVAX-TgMIC13 plasmid against acute and chronic Toxoplasma gondii infection in a murine model ZG Yuan, D Ren, DH Zhou, XX Zhang, E Petersen, XZ Li, Y Zhou, ... Vaccine 31 (31), 3135-3139, 2013 | 37 | 2013 |
The cardioprotective effects of carvedilol on ischemia and reperfusion injury by AMPK signaling pathway H Hu, X Li, D Ren, Y Tan, J Chen, L Yang, R Chen, J Li, P Zhu Biomedicine & Pharmacotherapy 117, 109106, 2019 | 36 | 2019 |
Sestrin2 modulates cardiac inflammatory response through maintaining redox homeostasis during ischemia and reperfusion D Ren, N Quan, J Fedorova, J Zhang, Z He, J Li Redox Biology 34, 101556, 2020 | 33 | 2020 |
The Interaction of mTOR and Nrf2 in Neurogenesis and Its Implication in Neurodegenerative Diseases LI Zoungrana, M Krause-Hauch, H Wang, MK Fatmi, L Bates, Z Li, ... Cells 11 (13), 2048, 2022 | 24 | 2022 |
The cardioprotective signaling activity of activated protein C in heart failure and ischemic heart diseases D Ren, H Giri, J Li, AR Rezaie International Journal of Molecular Sciences 20 (7), 1762, 2019 | 24 | 2019 |
Substrate metabolism regulated by Sestrin2–mTORC1 alleviates pressure overload-induced cardiac hypertrophy in aged heart N Quan, X Li, J Zhang, Y Han, W Sun, D Ren, Q Tong, J Li Redox Biology 36, 101637, 2020 | 20 | 2020 |
Nrf2 transcriptional upregulation of IDH2 to tune mitochondrial dynamics and rescue angiogenic function of diabetic EPCs X Dai, K Wang, J Fan, H Liu, X Fan, Q Lin, Y Chen, H Chen, Y Li, H Liu, ... Redox Biology 56, 102449, 2022 | 19 | 2022 |
Activated protein C strengthens cardiac tolerance to ischemic insults in aging D Ren, J Fedorova, K Davitt, TN Van Le, JH Griffin, PC Liaw, CT Esmon, ... Circulation research 130 (2), 252-272, 2022 | 18 | 2022 |
Sestrin2 maintains OXPHOS integrity to modulate cardiac substrate metabolism during ischemia and reperfusion D Ren, Z He, J Fedorova, J Zhang, E Wood, X Zhang, DE Kang, J Li Redox Biology 38, 101824, 2021 | 16 | 2021 |