Prebiotic peptides: Molecular hubs in the origin of life M Frenkel-Pinter, M Samanta, G Ashkenasy, LJ Leman Chemical reviews 120 (11), 4707-4765, 2020 | 239 | 2020 |
Root of the tree: the significance, evolution, and origins of the ribosome JC Bowman, AS Petrov, M Frenkel-Pinter, PI Penev, LD Williams Chemical reviews 120 (11), 4848-4878, 2020 | 142 | 2020 |
Inhibiting α-synuclein oligomerization by stable cell-penetrating β-synuclein fragments recovers phenotype of Parkinson's disease model flies R Shaltiel-Karyo, M Frenkel-Pinter, N Egoz-Matia, A Frydman-Marom, ... PloS one 5 (11), e13863, 2010 | 124 | 2010 |
A blood-brain barrier (BBB) disrupter is also a potent α-synuclein (α-syn) aggregation inhibitor: a novel dual mechanism of mannitol for the treatment of Parkinson disease (PD) R Shaltiel-Karyo, M Frenkel-Pinter, E Rockenstein, C Patrick, ... Journal of Biological Chemistry 288 (24), 17579-17588, 2013 | 115 | 2013 |
Interplay between protein glycosylation pathways in Alzheimer’s disease M Frenkel-Pinter, MD Shmueli, C Raz, M Yanku, S Zilberzwige, E Gazit, ... Science advances 3 (9), e1601576, 2017 | 106 | 2017 |
Selective incorporation of proteinaceous over nonproteinaceous cationic amino acids in model prebiotic oligomerization reactions M Frenkel-Pinter, JW Haynes, AS Petrov, BT Burcar, R Krishnamurthy, ... Proceedings of the National Academy of Sciences 116 (33), 16338-16346, 2019 | 99 | 2019 |
Mutually stabilizing interactions between proto-peptides and RNA M Frenkel-Pinter, JW Haynes, AM Mohyeldin, AB Sargon, AS Petrov, ... Nature communications 11 (1), 3137, 2020 | 78 | 2020 |
Water and Life: The Medium is the Message M Frenkel-Pinter, V Rajaei, JB Glass, NV Hud, LD Williams Journal of Molecular Evolution, 1-10, 2021 | 54 | 2021 |
Naphthoquinone-tryptophan hybrid inhibits aggregation of the tau-derived peptide PHF6 and reduces neurotoxicity M Frenkel-Pinter, S Tal, R Scherzer-Attali, M Abu-Hussien, I Alyagor, ... Journal of Alzheimer's Disease 51 (1), 165-178, 2016 | 50 | 2016 |
Selective inhibition of aggregation and toxicity of a Tau‐derived peptide using its glycosylated analogues M Frenkel‐Pinter, M Richman, A Belostozky, A Abu‐Mokh, E Gazit, ... Chemistry–A European Journal 22 (17), 5945-5952, 2016 | 45 | 2016 |
Differential inhibition of α-synuclein oligomeric and fibrillar assembly in parkinson's disease model by cinnamon extract R Shaltiel-Karyo, D Davidi, M Frenkel-Pinter, M Ovadia, D Segal, E Gazit Biochimica et Biophysica Acta (BBA)-General Subjects 1820 (10), 1628-1635, 2012 | 43 | 2012 |
Novel model of secreted human tau protein reveals the impact of the abnormal N-glycosylation of tau on its aggregation propensity Y Losev, A Paul, M Frenkel-Pinter, M Abu-Hussein, I Khalaila, E Gazit, ... Scientific reports 9 (1), 2254, 2019 | 40 | 2019 |
A Novel, Sensitive Assay for Behavioral Defects in Parkinson′s Disease Model Drosophila R Shaltiel-Karyo, D Davidi, Y Menuchin, M Frenkel-Pinter, ... Parkinson’s disease 2012 (1), 697564, 2012 | 35 | 2012 |
Thioesters provide a plausible prebiotic path to proto-peptides M Frenkel-Pinter, M Bouza, FM Fernández, LJ Leman, LD Williams, ... Nature communications 13 (1), 2569, 2022 | 34 | 2022 |
Tryptophan-galactosylamine conjugates inhibit and disaggregate amyloid fibrils of Aβ42 and hIAPP peptides while reducing their toxicity A Paul, M Frenkel-Pinter, D Escobar Alvarez, G Milordini, E Gazit, E Zacco, ... Communications Biology 3 (1), 484, 2020 | 34 | 2020 |
Differential effects of putative N-glycosylation sites in human Tau on Alzheimer’s disease-related neurodegeneration Y Losev, M Frenkel-Pinter, M Abu-Hussien, GK Viswanathan, ... Cellular and Molecular Life Sciences 78, 2231-2245, 2021 | 33 | 2021 |
Inhibition of the aggregation and toxicity of the minimal amyloidogenic fragment of tau by its pro‐substituted analogues M Chemerovski‐Glikman, M Frenkel‐Pinter, R Mdah, A Abu‐Mokh, ... Chemistry–A European Journal 23 (40), 9618-9624, 2017 | 29 | 2017 |
Cl-NQTrp alleviates tauopathy symptoms in a model organism through the inhibition of tau aggregation-engendered toxicity M Frenkel-Pinter, S Tal, R Scherzer-Attali, M Abu-Hussien, I Alyagor, ... Neurodegenerative Diseases 17 (2-3), 73-82, 2017 | 29 | 2017 |
Cutting in-line with iron: ribosomal function and non-oxidative RNA cleavage R Guth-Metzler, MS Bray, M Frenkel-Pinter, S Suttapitugsakul, ... Nucleic Acids Research, gkaa586, 2020 | 23 | 2020 |
The pH dependent mechanisms of non-enzymatic peptide bond cleavage reactions Y Sun, M Frenkel-Pinter, CL Liotta, MA Grover Physical Chemistry Chemical Physics 22 (1), 107-113, 2020 | 22 | 2020 |