Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell S Yui, T Nakamura, T Sato, Y Nemoto, T Mizutani, X Zheng, S Ichinose, ... Nature medicine 18 (4), 618-623, 2012 | 891 | 2012 |
YAP/TAZ-dependent reprogramming of colonic epithelium links ECM remodeling to tissue regeneration S Yui, L Azzolin, M Maimets, MT Pedersen, RP Fordham, SL Hansen, ... Cell stem cell 22 (1), 35-49. e7, 2018 | 547 | 2018 |
Transplantation of expanded fetal intestinal progenitors contributes to colon regeneration after injury RP Fordham, S Yui, NRF Hannan, C Soendergaard, A Madgwick, ... Cell stem cell 13 (6), 734-744, 2013 | 405 | 2013 |
Tracing the origin of adult intestinal stem cells J Guiu, E Hannezo, S Yui, S Demharter, S Ulyanchenko, M Maimets, ... Nature 570 (7759), 107-111, 2019 | 139 | 2019 |
Single cell analysis of Crohn’s disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties K Suzuki, T Murano, H Shimizu, G Ito, T Nakata, S Fujii, F Ishibashi, ... Journal of gastroenterology 53, 1035-1047, 2018 | 94 | 2018 |
Transplantation of intestinal organoids into a mouse model of colitis S Watanabe, S Kobayashi, N Ogasawara, R Okamoto, T Nakamura, ... Nature Protocols 17 (3), 649-671, 2022 | 64 | 2022 |
Hes1 promotes the IL-22-mediated antimicrobial response by enhancing STAT3-dependent transcription in human intestinal epithelial cells T Murano, R Okamoto, G Ito, T Nakata, S Hibiya, H Shimizu, S Fujii, ... Biochemical and biophysical research communications 443 (3), 840-846, 2014 | 54 | 2014 |
Real-time analysis of P-glycoprotein-mediated drug transport across primary intestinal epithelium three-dimensionally cultured in vitro T Mizutani, T Nakamura, R Morikawa, M Fukuda, W Mochizuki, ... Biochemical and biophysical research communications 419 (2), 238-243, 2012 | 52 | 2012 |
Lineage-specific expression of bestrophin-2 and bestrophin-4 in human intestinal epithelial cells G Ito, R Okamoto, T Murano, H Shimizu, S Fujii, T Nakata, T Mizutani, ... PloS one 8 (11), e79693, 2013 | 50 | 2013 |
Organoid-based regenerative medicine for inflammatory bowel disease R Okamoto, H Shimizu, K Suzuki, A Kawamoto, J Takahashi, M Kawai, ... Regenerative therapy 13, 1-6, 2020 | 47 | 2020 |
Ubiquitin D is upregulated by synergy of notch signalling and TNF-α in the inflamed intestinal epithelia of IBD patients A Kawamoto, S Nagata, S Anzai, J Takahashi, M Kawai, M Hama, ... Journal of Crohn's and Colitis 13 (4), 495-509, 2019 | 29 | 2019 |
Delta-like 1 expression promotes goblet cell differentiation in Notch-inactivated human colonic epithelial cells J Akiyama, R Okamoto, M Iwasaki, X Zheng, S Yui, K Tsuchiya, ... Biochemical and biophysical research communications 393 (4), 662-667, 2010 | 23 | 2010 |
Notch and TNF-α signaling promote cytoplasmic accumulation of OLFM4 in intestinal epithelium cells and exhibit a cell protective role in the inflamed mucosa of IBD patients R Kuno, G Ito, A Kawamoto, Y Hiraguri, HY Sugihara, S Takeoka, ... Biochemistry and Biophysics Reports 25, 100906, 2021 | 17 | 2021 |
Necrotizing enterocolitis: state of the art in translating experimental research to the bedside N Ganji, B Li, C Lee, R Filler, A Pierro European Journal of Pediatric Surgery 29 (04), 352-360, 2019 | 14 | 2019 |
Collagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation S Kobayashi, N Ogasawara, S Watanabe, Y Yoneyama, S Kirino, ... Inflammation and Regeneration 42 (1), 49, 2022 | 12 | 2022 |
TGF-β promotes fetal gene expression and cell migration velocity in a wound repair model of untransformed intestinal epithelial cells S Anzai, A Kawamoto, S Nagata, J Takahashi, M Kawai, R Kuno, ... Biochemical and biophysical research communications 524 (3), 533-541, 2020 | 11 | 2020 |
Fluorescent labelling of intestinal epithelial cells reveals independent long-lived intestinal stem cells in a crypt N Horita, K Tsuchiya, R Hayashi, K Fukushima, S Hibiya, M Fukuda, ... Biochemical and biophysical research communications 454 (4), 493-499, 2014 | 10 | 2014 |
Functional analysis of isoflavones using patient-derived human colonic organoids M Tsuchiya, G Ito, M Hama, S Nagata, A Kawamoto, K Suzuki, H Shimizu, ... Biochemical and Biophysical Research Communications 542, 40-47, 2021 | 4 | 2021 |
The effect of vitamin D3 and valproic acid on the maturation of human-induced pluripotent stem cell-derived enterocyte-like cells S Leo, Y Kato, Y Wu, M Yokota, M Koike, S Yui, K Tsuchiya, N Shiraki, ... Stem Cells 41 (8), 775-791, 2023 | 3 | 2023 |
Organoids transplantation as a new modality to design epithelial signature to create a membrane-protective sulfomucin-enriched segment S Watanabe, N Ogasawara, S Kobayashi, S Kirino, M Inoue, Y Hiraguri, ... Journal of Gastroenterology 58 (4), 379-393, 2023 | 3 | 2023 |