| CSF-1R inhibition alters macrophage polarization and blocks glioma progression SM Pyonteck, L Akkari, AJ Schuhmacher, RL Bowman, L Sevenich, ... Nature medicine 19 (10), 1264-1272, 2013 | 2216 | 2013 |
| Non-cell-autonomous tumor suppression by p53 A Lujambio, L Akkari, J Simon, D Grace, DF Tschaharganeh, JE Bolden, ... Cell 153 (2), 449-460, 2013 | 771 | 2013 |
| The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas DF Quail, RL Bowman, L Akkari, ML Quick, AJ Schuhmacher, JT Huse, ... Science 352 (6288), aad3018, 2016 | 595 | 2016 |
| Macrophage ontogeny underlies differences in tumor-specific education in brain malignancies RL Bowman, F Klemm, L Akkari, SM Pyonteck, L Sevenich, DF Quail, ... Cell reports 17 (9), 2445-2459, 2016 | 549 | 2016 |
| Inducing and exploiting vulnerabilities for the treatment of liver cancer C Wang, S Vegna, H Jin, B Benedict, C Lieftink, C Ramirez, ... Nature 574 (7777), 268-272, 2019 | 318 | 2019 |
| Metabolic origins of spatial organization in the tumor microenvironment C Carmona-Fontaine, M Deforet, L Akkari, CB Thompson, JA Joyce, ... Proceedings of the National Academy of Sciences 114 (11), 2934-2939, 2017 | 294 | 2017 |
| Obesity alters the lung myeloid cell landscape to enhance breast cancer metastasis through IL5 and GM-CSF DF Quail, OC Olson, P Bhardwaj, LA Walsh, L Akkari, ML Quick, IC Chen, ... Nature cell biology 19 (8), 974-987, 2017 | 242 | 2017 |
| EGFR activation limits the response of liver cancer to lenvatinib H Jin, Y Shi, Y Lv, S Yuan, CFA Ramirez, C Lieftink, L Wang, S Wang, ... Nature 595 (7869), 730-734, 2021 | 235 | 2021 |
| Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance L Akkari, RL Bowman, J Tessier, F Klemm, SM Handgraaf, M de Groot, ... Science translational medicine 12 (552), eaaw7843, 2020 | 216 | 2020 |
| Long-term analysis of the NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with PCV or temozolomide W Wick, P Roth, C Hartmann, P Hau, M Nakamura, F Stockhammer, ... Neuro-oncology 18 (11), 1529-1537, 2016 | 209 | 2016 |
| Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas D Yan, J Kowal, L Akkari, AJ Schuhmacher, JT Huse, BL West, JA Joyce Oncogene 36 (43), 6049-6058, 2017 | 204 | 2017 |
| Emergence of spatial structure in the tumor microenvironment due to the Warburg effect C Carmona-Fontaine, V Bucci, L Akkari, M Deforet, JA Joyce, JB Xavier Proceedings of the National Academy of Sciences 110 (48), 19402-19407, 2013 | 151 | 2013 |
| mTOR regulates phagosome and entotic vacuole fission M Krajcovic, S Krishna, L Akkari, JA Joyce, M Overholtzer Molecular biology of the cell 24 (23), 3736-3745, 2013 | 146 | 2013 |
| Single-cell spatial immune landscapes of primary and metastatic brain tumours E Karimi, MW Yu, SM Maritan, LJM Perus, M Rezanejad, M Sorin, ... Nature 614 (7948), 555-563, 2023 | 131 | 2023 |
| Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix L Akkari, V Gocheva, JC Kester, KE Hunter, ML Quick, L Sevenich, ... Genes & development 28 (19), 2134-2150, 2014 | 121 | 2014 |
| The oncogenic action of NRF2 depends on de-glycation by fructosamine-3-kinase VR Sanghvi, J Leibold, M Mina, P Mohan, M Berishaj, Z Li, MM Miele, ... Cell 178 (4), 807-819. e21, 2019 | 110 | 2019 |
| A carbon nanotube optical reporter maps endolysosomal lipid flux PV Jena, D Roxbury, TV Galassi, L Akkari, CP Horoszko, DB Iaea, ... ACS nano 11 (11), 10689-10703, 2017 | 108 | 2017 |
| Macrophages at the interface of the co-evolving cancer ecosystem DJ Kloosterman, L Akkari Cell 186 (8), 1627-1651, 2023 | 87 | 2023 |
| Hepatitis C viral protein NS5A induces EMT and participates in oncogenic transformation of primary hepatocyte precursors L Akkari, D Grégoire, N Floc’h, M Moreau, C Hernandez, Y Simonin, ... Journal of hepatology 57 (5), 1021-1028, 2012 | 82 | 2012 |
| Innate immune cells in the tumor microenvironment MO Li, N Wolf, DH Raulet, L Akkari, MJ Pittet, PC Rodriguez, RN Kaplan, ... Cancer Cell 39 (6), 725-729, 2021 | 81 | 2021 |
