| A population of gut epithelial enterochromaffin cells is mechanosensitive and requires Piezo2 to convert force into serotonin release C Alcaino, KR Knutson, AJ Treichel, G Yildiz, PR Strege, DR Linden, JH Li, ... Proceedings of the National Academy of Sciences 115 (32), E7632-E7641, 2018 | 236 | 2018 |
| Mechanosensitive ion channel Piezo2 is important for enterochromaffin cell response to mechanical forces F Wang, K Knutson, C Alcaino, DR Linden, SJ Gibbons, P Kashyap, ... The Journal of physiology 595 (1), 79-91, 2017 | 176 | 2017 |
| Mechanosensitive piezo channels in the gastrointestinal tract C Alcaino, G Farrugia, A Beyder Current topics in membranes 79, 219-244, 2017 | 83 | 2017 |
| Mechanosensitive ion channel Piezo2 is inhibited by D-GsMTx4 C Alcaino, K Knutson, PA Gottlieb, G Farrugia, A Beyder Channels 11 (3), 245-253, 2017 | 75 | 2017 |
| Specialized mechanosensory epithelial cells in mouse gut intrinsic tactile sensitivity AJ Treichel, I Finholm, KR Knutson, C Alcaino, ST Whiteman, MR Brown, ... Gastroenterology 162 (2), 535-547. e13, 2022 | 54 | 2022 |
| Non-equivalent ligand selectivity of agonist sites in (α4β2) 2α4 nicotinic acetylcholine receptors: a key determinant of agonist efficacy S Mazzaferro, F Gasparri, K New, C Alcaino, M Faundez, PI Vasquez, ... Journal of Biological Chemistry 289 (31), 21795-21806, 2014 | 47 | 2014 |
| The additional ACh binding site at the α4(+)/α4(−) interface of the (α4β2)2α4 nicotinic ACh receptor contributes to desensitization N Benallegue, S Mazzaferro, C Alcaino, I Bermudez British journal of pharmacology 170 (2), 304-316, 2013 | 35 | 2013 |
| Role of the cys loop and transmembrane domain in the allosteric modulation of α4β2 nicotinic acetylcholine receptors C Alcaino, M Musgaard, T Minguez, S Mazzaferro, M Faundez, ... Journal of Biological Chemistry 292 (2), 551-562, 2017 | 32 | 2017 |
| microRNA overexpression in slow transit constipation leads to reduced NaV1. 5 current and altered smooth muscle contractility A Mazzone, PR Strege, SJ Gibbons, C Alcaino, V Joshi, AJ Haak, ... Gut 69 (5), 868-876, 2020 | 23 | 2020 |
| NACHO and 14-3-3 promote expression of distinct subunit stoichiometries of the α4β2 acetylcholine receptor S Mazzaferro, ST Whiteman, C Alcaino, A Beyder, SM Sine Cellular and Molecular Life Sciences 78, 1565-1575, 2021 | 16 | 2021 |
| Allosteric modulators of α4β2 nicotinic acetylcholine receptors: a new direction for antidepressant drug discovery E Mantione, S Micheloni, C Alcaino, K New, S Mazzaferro, I Bermudez Future Medicinal Chemistry 4 (17), 2217-2230, 2012 | 15 | 2012 |
| Foundation one genomic interrogation of thyroid cancers in patients with metastatic disease requiring systemic therapy NM Iñiguez-Ariza, S Jasim, MM Ryder, AV Chintakuntlawar, JC Morris III, ... The Journal of Clinical Endocrinology & Metabolism 105 (7), e2346-e2357, 2020 | 13 | 2020 |
| Identification of intrinsic primary afferent neurons in mouse jejunum CGS Melo, EN Nicolai, C Alcaino, TJ Cassmann, ST Whiteman, ... Neurogastroenterology & Motility 32 (12), e13989, 2020 | 12 | 2020 |
| Intestinal enteroendocrine cells rely on ryanodine and IP3 calcium store receptors for mechanotransduction KR Knutson, ST Whiteman, C Alcaino, A Mercado‐Perez, I Finholm, ... The Journal of physiology 601 (2), 287-305, 2023 | 10 | 2023 |
| The additional acetylcholine binding site at the α4 (+)/α4 (−) interface of the (α4β2) 2α4 nicotinic acetylcholine receptor contributes to desensitisation N Benallegue, S Mazzaferro, C Alcaino, I Bermudez Br J Pharmacol 170, 304-316, 2013 | 6 | 2013 |
| Mechanosensitive pore opening of a prokaryotic voltage-gated sodium channel PR Strege, LM Cowan, C Alcaino, A Mazzone, CA Ahern, LS Milescu, ... Elife 12, e79271, 2023 | 5 | 2023 |
| The fifth subunit of the (α4β2)2β2 nicotinic ACh receptor modulates maximal ACh responses K New, SG Del Villar, S Mazzaferro, C Alcaino, I Bermudez British Journal of Pharmacology 175 (11), 1822-1837, 2018 | 5 | 2018 |
| Molecular mechanisms underlying glucose-dependent insulinotropic polypeptide secretion in human duodenal organoids N Guccio, C Alcaino, EL Miedzybrodzka, M Santos-Hernández, CA Smith, ... Diabetologia, 1-14, 2024 | 3 | 2024 |
| The mechanosensitive ion channel Piezo2 is selectively expressed in enterochromaffin (EC) cells of the human and mouse gastrointestinal mucosa K Knutson, F Wang, C Alcaino, C Bernard, G Farrugia, A Beyder The FASEB Journal 30, 1254.5-1254.5, 2016 | 2 | 2016 |
| XVIIth Little Brain Big Brain: an extraordinary meeting in extraordinary times C Alcaino, F Carbone, PH Neckel, NEB Tjaden Nature Reviews Gastroenterology & Hepatology 20 (4), 197-198, 2023 | 1 | 2023 |
