PCR-based approach targeting mucorales-specific gene family for diagnosis of mucormycosis C Baldin, SSM Soliman, HH Jeon, S Alkhazraji, T Gebremariam, Y Gu, ... Journal of Clinical Microbiology 56 (10), 10.1128/jcm. 00746-18, 2018 | 110 | 2018 |
GRP78 and integrins play different roles in host cell invasion during mucormycosis A Alqarihi, T Gebremariam, Y Gu, M Swidergall, S Alkhazraji, ... MBio 11 (3), 10.1128/mbio. 01087-20, 2020 | 78 | 2020 |
Fosmanogepix (APX001) is effective in the treatment of immunocompromised mice infected with invasive pulmonary scedosporiosis or disseminated fusariosis S Alkhazraji, T Gebremariam, A Alqarihi, Y Gu, Z Mamouei, S Singh, ... Antimicrobial agents and chemotherapy 64 (3), 10.1128/aac. 01735-19, 2020 | 74 | 2020 |
Anti-CotH3 antibodies protect mice from mucormycosis by prevention of invasion and augmenting opsonophagocytosis T Gebremariam, S Alkhazraji, SSM Soliman, Y Gu, HH Jeon, L Zhang, ... Science advances 5 (6), eaaw1327, 2019 | 68 | 2019 |
Mucoricin is a ricin-like toxin that is critical for the pathogenesis of mucormycosis SSM Soliman, C Baldin, Y Gu, S Singh, T Gebremariam, M Swidergall, ... Nature microbiology 6 (3), 313-326, 2021 | 60 | 2021 |
Fosmanogepix (APX001) is effective in the treatment of pulmonary murine mucormycosis due to Rhizopus arrhizus T Gebremariam, S Alkhazraji, A Alqarihi, NP Wiederhold, KJ Shaw, ... Antimicrobial agents and chemotherapy 64 (6), 10.1128/aac. 00178-20, 2020 | 60 | 2020 |
Inhibition of EGFR signaling protects from mucormycosis TN Watkins, T Gebremariam, M Swidergall, AC Shetty, KT Graf, A Alqarihi, ... MBio 9 (4), 10.1128/mbio. 01384-18, 2018 | 50 | 2018 |
The Hyr1 protein from the fungus Candida albicans is a cross kingdom immunotherapeutic target for Acinetobacter bacterial infection P Uppuluri, L Lin, A Alqarihi, G Luo, EG Youssef, S Alkhazraji, NY Yount, ... PLoS pathogens 14 (5), e1007056, 2018 | 44 | 2018 |
APX001 is effective in the treatment of murine invasive pulmonary aspergillosis T Gebremariam, S Alkhazraji, A Alqarihi, HH Jeon, Y Gu, M Kapoor, ... Antimicrobial agents and chemotherapy 63 (2), 10.1128/aac. 01713-18, 2019 | 43 | 2019 |
Prophylactic treatment with VT-1161 protects immunosuppressed mice from Rhizopus arrhizus var. arrhizus infection T Gebremariam, S Alkhazraji, L Lin, NP Wiederhold, EP Garvey, ... Antimicrobial agents and chemotherapy 61 (9), 10.1128/aac. 00390-17, 2017 | 38 | 2017 |
Prophylaxis with isavuconazole or posaconazole protects immunosuppressed mice from pulmonary mucormycosis T Gebremariam, S Alkhazraji, C Baldin, L Kovanda, NP Wiederhold, ... Antimicrobial agents and chemotherapy 61 (5), 10.1128/aac. 02589-16, 2017 | 28 | 2017 |
The combination treatment of fosmanogepix and liposomal amphotericin B is superior to monotherapy in treating experimental invasive mold infections T Gebremariam, Y Gu, S Alkhazraji, E Youssef, KJ Shaw, AS Ibrahim Antimicrobial Agents and Chemotherapy 66 (7), e00380-22, 2022 | 26 | 2022 |
A host defense peptide mimetic, brilacidin, potentiates caspofungin antifungal activity against human pathogenic fungi TF Dos Reis, PA De Castro, RW Bastos, CF Pinzan, PFN Souza, S Ackloo, ... Nature communications 14 (1), 2052, 2023 | 25 | 2023 |
Monoclonal IgM Antibodies Targeting Candida albicans Hyr1 Provide Cross-Kingdom Protection Against Gram-Negative Bacteria EG Youssef, L Zhang, S Alkhazraji, T Gebremariam, S Singh, NY Yount, ... Frontiers in Immunology 11, 76, 2020 | 13 | 2020 |
APX001A Protects Immunosuppressed Mice from Rhizopus delemar Infection T Gebremariam, S Alkhazraji, A Alqarihi, NP Wiederhold, KJ Shaw, ... Open Forum Infectious Diseases 4 (suppl_1), S475-S475, 2017 | 13 | 2017 |
Galactomannan is a biomarker of fosmanogepix (APX001) efficacy in treating experimental invasive pulmonary aspergillosis T Gebremariam, S Alkhazraji, Y Gu, S Singh, A Alqarihi, KJ Shaw, ... Antimicrobial agents and chemotherapy 64 (1), 10.1128/aac. 01966-19, 2019 | 11 | 2019 |
Anti-CotH3 antibodies protect mice from mucormycosis by prevention of invasion and augmenting opsonophagocytosis. Sci Adv 5: eaaw1327 T Gebremariam, S Alkhazraji, SSM Soliman, Y Gu, HH Jeon, L Zhang, ... | 10 | 2019 |
Evaluation of sex differences in murine diabetic ketoacidosis and neutropenic models of invasive mucormycosis T Gebremariam, S Alkhazraji, A Alqarihi, NP Wiederhold, LK Najvar, ... Journal of Fungi 7 (4), 313, 2021 | 9 | 2021 |
Preserving vascular integrity protects mice against multidrug-resistant gram-negative bacterial infection T Gebremariam, L Zhang, S Alkhazraji, Y Gu, EG Youssef, Z Tong, ... Antimicrobial Agents and Chemotherapy 64 (8), 10.1128/aac. 00303-20, 2020 | 9 | 2020 |
Inhibition of EGFR signaling protects from mucormycosis. mBio 9: e01384-18 TN Watkins, T Gebremariam, M Swidergall, AC Shetty, KT Graf, A Alqarihi, ... | 8 | 2018 |