TRIM21—from intracellular immunity to therapy S Foss, M Bottermann, A Jonsson, I Sandlie, LC James, JT Andersen Frontiers in Immunology 10, 2049, 2019 | 132 | 2019 |
Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn RF Hallstensen, G Bergseth, S Foss, S Jæger, T Gedde-Dahl, J Holt, ... Immunobiology 220 (4), 452-459, 2015 | 126 | 2015 |
TRIM 21: a cytosolic Fc receptor with broad antibody isotype specificity S Foss, R Watkinson, I Sandlie, LC James, JT Andersen Immunological reviews 268 (1), 328-339, 2015 | 114 | 2015 |
Plasma cells are the most abundant gluten peptide MHC-expressing cells in inflamed intestinal tissues from patients with celiac disease LS Høydahl, L Richter, R Frick, O Snir, KS Gunnarsen, OJB Landsverk, ... Gastroenterology 156 (5), 1428-1439. e10, 2019 | 85 | 2019 |
Fc engineering of human IgG1 for altered binding to the neonatal Fc receptor affects Fc effector functions A Grevys, M Bern, S Foss, DB Bratlie, A Moen, KS Gunnarsen, A Aase, ... The Journal of Immunology 194 (11), 5497-5508, 2015 | 79 | 2015 |
A human endothelial cell-based recycling assay for screening of FcRn targeted molecules A Grevys, J Nilsen, KMK Sand, MB Daba, I Øynebråten, M Bern, ... Nature Communications 9 (1), 621, 2018 | 74 | 2018 |
Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity SL Caddy, M Vaysburd, G Papa, M Wing, K O’Connell, D Stoycheva, ... The EMBO journal 40 (5), e106228, 2021 | 69 | 2021 |
Intracellular neutralisation of rotavirus by VP6-specific IgG SL Caddy, M Vaysburd, M Wing, S Foss, JT Andersen, K Mayes, ... PLoS pathogens 16 (8), e1008732, 2020 | 69 | 2020 |
Complement C4 prevents viral infection through capsid inactivation M Bottermann, S Foss, SL Caddy, D Clift, LM van Tienen, M Vaysburd, ... Cell host & microbe 25 (4), 617-629. e7, 2019 | 65 | 2019 |
An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics M Bern, J Nilsen, M Ferrarese, KMK Sand, TT Gjølberg, HE Lode, ... Science translational medicine 12 (565), eabb0580, 2020 | 58 | 2020 |
TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination M Bottermann, S Foss, LM van Tienen, M Vaysburd, J Cruickshank, ... Proceedings of the National Academy of Sciences 115 (41), 10440-10445, 2018 | 56 | 2018 |
Dissection of the neonatal Fc receptor (FcRn)-albumin interface using mutagenesis and anti-FcRn albumin-blocking antibodies KMK Sand, B Dalhus, GJ Christianson, M Bern, S Foss, J Cameron, ... Journal of Biological Chemistry 289 (24), 17228-17239, 2014 | 52 | 2014 |
Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross … JT Andersen, S Foss, VE Kenanova, T Olafsen, IS Leikfoss, ... Journal of Biological Chemistry 287 (27), 22927-22937, 2012 | 46 | 2012 |
TRIM21 immune signaling is more sensitive to antibody affinity than its neutralization activity S Foss, RE Watkinson, A Grevys, MB McAdam, M Bern, LS Høydahl, ... The Journal of Immunology 196 (8), 3452-3459, 2016 | 45 | 2016 |
Enhanced FcRn-dependent transepithelial delivery of IgG by Fc-engineering and polymerization S Foss, A Grevys, KMK Sand, M Bern, P Blundell, TE Michaelsen, ... Journal of Controlled Release 223, 42-52, 2016 | 44 | 2016 |
A new method for pharmaceutical compounding and storage of anti-VEGF biologics for intravitreal use in silicone oil-free prefilled plastic syringes HE Lode, TT Gjølberg, S Foss, MS Sivertsen, J Brustugun, Y Andersson, ... Scientific reports 9 (1), 18021, 2019 | 43 | 2019 |
FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex–driven autoimmunity JJ Hubbard, M Pyzik, T Rath, LK Kozicky, KMK Sand, AK Gandhi, ... Journal of Experimental Medicine 217 (10), 2020 | 39 | 2020 |
Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection LI Labzin, M Bottermann, P Rodriguez‐Silvestre, S Foss, JT Andersen, ... The EMBO Journal 38 (21), e101365, 2019 | 39 | 2019 |
Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models AS Mukadam, LVC Miller, AE Smith, M Vaysburd, SA Sakya, S Sanford, ... Science 379 (6639), 1336-1341, 2023 | 37 | 2023 |
Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life A Grevys, R Frick, S Mester, K Flem-Karlsen, J Nilsen, S Foss, KMK Sand, ... Iscience 25 (2), 2022 | 37 | 2022 |