TREM2 lipid sensing sustains the microglial response in an Alzheimer’s disease model Y Wang, M Cella, K Mallinson, JD Ulrich, KL Young, ML Robinette, ... Cell 160 (6), 1061-1071, 2015 | 1566 | 2015 |
IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia Y Wang, KJ Szretter, W Vermi, S Gilfillan, C Rossini, M Cella, AD Barrow, ... Nature immunology 13 (8), 753-760, 2012 | 1040 | 2012 |
TREM2 maintains microglial metabolic fitness in Alzheimer’s disease TK Ulland, WM Song, SCC Huang, JD Ulrich, A Sergushichev, WL Beatty, ... Cell 170 (4), 649-663. e13, 2017 | 941 | 2017 |
TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques Y Wang, TK Ulland, JD Ulrich, W Song, JA Tzaferis, JT Hole, P Yuan, ... Journal of Experimental Medicine 213 (5), 667-675, 2016 | 757 | 2016 |
TREM2 haplodeficiency in mice and humans impairs the microglia barrier function leading to decreased amyloid compaction and severe axonal dystrophy P Yuan, C Condello, CD Keene, Y Wang, TD Bird, SM Paul, W Luo, ... Neuron 90 (4), 724-739, 2016 | 752 | 2016 |
Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets ML Robinette, A Fuchs, VS Cortez, JS Lee, Y Wang, SK Durum, S Gilfillan, ... Nature immunology 16 (3), 306-317, 2015 | 655 | 2015 |
TREM2 sustains microglial expansion during aging and response to demyelination PL Poliani, Y Wang, E Fontana, ML Robinette, Y Yamanishi, S Gilfillan, ... The Journal of clinical investigation 125 (5), 2161-2170, 2015 | 465 | 2015 |
Plasmacytoid dendritic cell ablation impacts early interferon responses and antiviral NK and CD8+ T cell accrual M Swiecki, S Gilfillan, W Vermi, Y Wang, M Colonna Immunity 33 (6), 955-966, 2010 | 442 | 2010 |
TREM2 variants: new keys to decipher Alzheimer disease pathogenesis M Colonna, Y Wang Nature Reviews Neuroscience 17 (4), 201-207, 2016 | 407 | 2016 |
Therapeutic B cell depletion impairs adaptive and autoreactive CD4+ T cell activation in mice JD Bouaziz, K Yanaba, GM Venturi, Y Wang, RM Tisch, JC Poe, ... Proceedings of the National Academy of Sciences 104 (52), 20878-20883, 2007 | 382 | 2007 |
Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2 JD Ulrich, MB Finn, Y Wang, A Shen, TE Mahan, H Jiang, FR Stewart, ... Molecular neurodegeneration 9, 1-9, 2014 | 327 | 2014 |
B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in FcγR effector functions Y Xiu, CP Wong, JD Bouaziz, Y Hamaguchi, Y Wang, SM Pop, RM Tisch, ... The Journal of Immunology 180 (5), 2863-2875, 2008 | 277 | 2008 |
Alzheimer's disease‐associated TREM2 variants exhibit either decreased or increased ligand‐dependent activation W Song, B Hooli, K Mullin, SC Jin, M Cella, TK Ulland, Y Wang, RE Tanzi, ... Alzheimer's & Dementia 13 (4), 381-387, 2017 | 246 | 2017 |
ApoE facilitates the microglial response to amyloid plaque pathology JD Ulrich, TK Ulland, TE Mahan, S Nyström, KP Nilsson, WM Song, ... Journal of Experimental Medicine 215 (4), 1047-1058, 2018 | 240 | 2018 |
Transforming growth factor-β signaling guides the differentiation of innate lymphoid cells in salivary glands VS Cortez, L Cervantes-Barragan, ML Robinette, JK Bando, Y Wang, ... Immunity 44 (5), 1127-1139, 2016 | 224 | 2016 |
Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo M Swiecki, Y Wang, W Vermi, S Gilfillan, RD Schreiber, M Colonna Journal of Experimental Medicine 208 (12), 2367-2374, 2011 | 187 | 2011 |
Timing and magnitude of type I interferon responses by distinct sensors impact CD8 T cell exhaustion and chronic viral infection Y Wang, M Swiecki, M Cella, G Alber, RD Schreiber, S Gilfillan, ... Cell host & microbe 11 (6), 631-642, 2012 | 178 | 2012 |
MerTK is required for apoptotic cell–induced T cell tolerance MA Wallet, P Sen, RR Flores, Y Wang, Z Yi, Y Huang, CE Mathews, ... The Journal of experimental medicine 205 (1), 219-232, 2008 | 169 | 2008 |
Interkeukin‐34, a cytokine crucial for the differentiation and maintenance of tissue resident macrophages and L angerhans cells Y Wang, M Colonna European journal of immunology 44 (6), 1575-1581, 2014 | 113 | 2014 |
Cutting edge: polyinosinic: polycytidylic acid boosts the generation of memory CD8 T cells through melanoma differentiation-associated protein 5 expressed in stromal cells Y Wang, M Cella, S Gilfillan, M Colonna The Journal of Immunology 184 (6), 2751-2755, 2010 | 110 | 2010 |