Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity B Prinzing, CC Zebley, CT Petersen, Y Fan, AA Anido, Z Yi, P Nguyen, ... Science translational medicine 13 (620), eabh0272, 2021 | 176 | 2021 |
Elimination of huntingtin in the adult mouse leads to progressive behavioral deficits, bilateral thalamic calcification, and altered brain iron homeostasis P Dietrich, IM Johnson, S Alli, I Dragatsis PLoS genetics 13 (7), e1006846, 2017 | 96 | 2017 |
Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes HA Abdelsamed, CC Zebley, H Nguyen, RL Rutishauser, Y Fan, ... Nature immunology 21 (5), 578-587, 2020 | 86 | 2020 |
CD19-CAR T cells undergo exhaustion DNA methylation programming in patients with acute lymphoblastic leukemia CC Zebley, C Brown, T Mi, Y Fan, S Alli, S Boi, G Galletti, E Lugli, ... Cell reports 37 (9), 2021 | 61 | 2021 |
IKAP expression levels modulate disease severity in a mouse model of familial dysautonomia P Dietrich, S Alli, R Shanmugasundaram, I Dragatsis Human molecular genetics 21 (23), 5078-5090, 2012 | 57 | 2012 |
Adipose stem cells and their paracrine factors are therapeutic for early retinal complications of diabetes in the Ins2Akita mouse SL Elshaer, W Evans, M Pentecost, R Lenin, R Periasamy, KA Jha, S Alli, ... Stem Cell Research & Therapy 9, 1-18, 2018 | 49 | 2018 |
Sensory and autonomic deficits in a new humanized mouse model of familial dysautonomia E Morini, P Dietrich, M Salani, HM Downs, GR Wojtkiewicz, S Alli, ... Human Molecular Genetics 25 (6), 1116-1128, 2016 | 42 | 2016 |
Proinflammatory cytokines promote TET2-mediated DNA demethylation during CD8 T cell effector differentiation CC Zebley, HA Abdelsamed, HE Ghoneim, S Alli, C Brown, D Haydar, ... Cell reports 37 (2), 2021 | 23 | 2021 |
Critical role of endoplasmic reticulum stress in chronic endothelial activation− induced visual deficits in tie2‐tumor necrosis factor mice R Lenin, PG Nagy, S Alli, VR Rao, MA Clauss, UB Kompella, R Gangaraju Journal of cellular biochemistry 119 (10), 8460-8471, 2018 | 20 | 2018 |
Prevention and treatment of secretory diarrhea by the lysophosphatidic acid analog Rx100 KE Thompson, RM Ray, S Alli, W Ge, A Boler, W Shannon McCool, ... Experimental Biology and Medicine 243 (13), 1056-1065, 2018 | 12 | 2018 |
Identification of cyclin D1 as a major modulator of 3-nitropropionic acid-induced striatal neurodegeneration P Dietrich, S Alli, MK Mulligan, R Cox, DG Ashbrook, RW Williams, ... Neurobiology of disease 162, 105581, 2022 | 11 | 2022 |
Antigen cross-presentation in young tumor-bearing hosts promotes CD8+ T cell terminal differentiation A Moustaki, JC Crawford, S Alli, Y Fan, S Boi, AE Zamora, ... Science immunology 7 (68), eabf6136, 2022 | 8 | 2022 |
Antitumor progenitor exhausted CD8+ T cells are sustained by TCR engagement X Lan, T Mi, S Alli, C Guy, MN Djekidel, X Liu, S Boi, P Chowdhury, M He, ... Nature Immunology, 1-13, 2024 | 2 | 2024 |
Conserved epigenetic hallmarks of T cell aging during immunity and malignancy T Mi, AG Soerens, S Alli, TG Kang, AB Vasandan, Z Wang, V Vezys, ... Nature Aging, 1-11, 2024 | 1 | 2024 |
ASXL1 disruption preserves CD8 T cell exhaustion-progenitor epigenetic programming during chronic stimulation TG Kang, X Lan, S Alli, CL O’Connell, K Gronbaek, P Jones, JH Han, ... The Journal of Immunology 210 (1_Supplement), 226.10-226.10, 2023 | 1 | 2023 |
IL-12 signaling promotes TET2-mediated DNA demethylation during CD8 T cell effector differentiation CC Zebley, HA Abdelsamed, HE Ghoneim, S Alli, D Haydar, T Harris, ... bioRxiv, 2020.11. 02.365148, 2020 | 1 | 2020 |
1516 Advancing immunotherapy through patient-identified regulators of T cell stemness C Zebley, TG Kang, T Mi, S Alli, G Ward, AB Vasandan, S Carson, X Lan, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 2), 2023 | | 2023 |
Conserved epigenetic hallmarks of T-cell age CC Zebley, T Mi, A Soerens, S Alli, A Vasandan, C Hines, A Mueller, ... The Journal of Immunology 210 (1_Supplement), 148.07-148.07, 2023 | | 2023 |
YIA23-001: Targeting NKG2D Ligands Is Therapeutically Effective in NSCLC Q Deng, MJ Lee, F Fattah, S Koyama, D Gerber, E Akbay Journal of the National Comprehensive Cancer Network 21 (3.5), YIA23-001 …, 2023 | | 2023 |
YIA23-003: CD19-CAR T Cells Develop Exhaustion Epigenetic Programs During a Clinical Response C Zebley, CC Brown, T Mi, Y Fan, S Alli, S Boi, G Galletti, E Lugli, ... Journal of the National Comprehensive Cancer Network 21 (3.5), YIA23-003 …, 2023 | | 2023 |