| N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation Y Cheng, W Xie, BF Pickering, KL Chu, AM Savino, X Yang, H Luo, ... Cancer cell 39 (7), 958-972. e8, 2021 | 155 | 2021 |
| Ciprofloxacin-modified electrosynthesized hydrogel coatings to prevent titanium-implant-associated infections MMB E De Giglio, S Cometa, MA Ricci, D Cafagna, AM Savino, L Sabbatini, M ... Acta biomaterialia 7 (2), 882-891, 2011 | 113 | 2011 |
| Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome O Schwartzman, AM Savino, M Gombert, C Palmi, G Cario, M Schrappe, ... Proceedings of the National Academy of Sciences 114 (20), E4030-E4039, 2017 | 84 | 2017 |
| High fructose drives the serine synthesis pathway in acute myeloid leukemic cells S Jeong, AM Savino, R Chirayil, E Barin, Y Cheng, SM Park, A Schurer, ... Cell metabolism 33 (1), 145-159. e6, 2021 | 47 | 2021 |
| The histone deacetylase inhibitor givinostat (ITF2357) exhibits potent anti-tumor activity against CRLF2-rearranged BCP-ALL AM Savino, J Sarno, L Trentin, M Vieri, G Fazio, M Bardini, C Bugarin, ... Leukemia 31 (11), 2365-2375, 2017 | 47 | 2017 |
| Metabolic adaptation of acute lymphoblastic leukemia to the central nervous system microenvironment depends on stearoyl-CoA desaturase AM Savino, SI Fernandes, O Olivares, A Zemlyansky, A Cousins, ... Nature cancer 1 (10), 998-1009, 2020 | 45 | 2020 |
| HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells DTT Nguyen, Y Lu, KL Chu, X Yang, SM Park, ZN Choo, CR Chin, ... Nature Communications 11 (1), 2026, 2020 | 45 | 2020 |
| Pharmacological administration of recombinant human AMH rescues ovarian reserve and preserves fertility in a mouse model of chemotherapy, without interfering with anti-tumoural … H Roness, I Spector, Y Leichtmann-Bardoogo, AM Savino, S Dereh-Haim, ... Journal of assisted reproduction and genetics 36, 1793-1803, 2019 | 44 | 2019 |
| Fine tuning of surface CRLF2 expression and its associated signaling profile in childhood B-cell precursor acute lymphoblastic leukemia C Bugarin, J Sarno, C Palmi, AM Savino, G te Kronnie, M Dworzak, ... Haematologica 100 (6), e229, 2015 | 36 | 2015 |
| Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1G93A astrocytes V Granatiero, NM Sayles, AM Savino, C Konrad, MG Kharas, H Kawamata, ... Autophagy 17 (12), 4029-4042, 2021 | 34 | 2021 |
| CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia C Palmi, AM Savino, D Silvestri, I Bronzini, G Cario, M Paganin, B Buldini, ... Oncotarget 7 (37), 59260, 2016 | 32 | 2016 |
| Antileukemic Efficacy of BET Inhibitor in a Preclinical Mouse Model of MLL-AF4+ Infant ALL M Bardini, L Trentin, F Rizzo, M Vieri, AM Savino, P Garrido Castro, ... Molecular Cancer Therapeutics 17 (8), 1705-1716, 2018 | 23 | 2018 |
| An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia I Geron, AM Savino, H Fishman, N Tal, J Brown, VA Turati, C James, ... Nature communications 13 (1), 659, 2022 | 21 | 2022 |
| Transcriptional control of CBX5 by the RNA-binding proteins RBMX and RBMXL1 maintains chromatin state in myeloid leukemia C Prieto, DTT Nguyen, Z Liu, J Wheat, A Perez, S Gourkanti, T Chou, ... Nature cancer 2 (7), 741-757, 2021 | 20 | 2021 |
| Impact of IKZF1 deletions on IKZF1 expression and outcome in Philadelphia chromosome negative childhood BCP-ALL. Reply to “incidence and biological significance of IKZF1/Ikaros … C Palmi, T Lana, D Silvestri, A Savino, G Te Kronnie, V Conter, G Basso, ... Haematologica 98 (12), e164, 2013 | 20 | 2013 |
| SRC/ABL inhibition disrupts CRLF2-driven signaling to induce cell death in B-cell acute lymphoblastic leukemia J Sarno, AM Savino, C Buracchi, C Palmi, S Pinto, C Bugarin, A Jager, ... Oncotarget 9 (33), 22872, 2018 | 16 | 2018 |
| Cytoskeletal regulatory gene expression and migratory properties of B-cell progenitors are affected by the ETV6–RUNX1 rearrangement C Palmi, G Fazio, AM Savino, J Procter, L Howell, V Cazzaniga, M Vieri, ... Molecular cancer research 12 (12), 1796-1806, 2014 | 15 | 2014 |
| PAX5 fusion genes are frequent in poor risk childhood acute lymphoblastic leukaemia and can be targeted with BIBF1120 G Fazio, S Bresolin, D Silvestri, M Quadri, C Saitta, E Vendramini, ... EBioMedicine 83, 2022 | 13 | 2022 |
| Interleukin-7 signaling as a therapeutic target in acute lymphoblastic leukemia AM Savino, S Izraeli Expert review of hematology 10 (3), 183-185, 2017 | 12 | 2017 |
| High-throughput screening as a drug repurposing strategy for poor outcome subgroups of pediatric B-cell precursor Acute Lymphoblastic Leukemia A Oikonomou, L Valsecchi, M Quadri, T Watrin, K Scharov, S Procopio, ... Biochemical Pharmacology 217, 115809, 2023 | 7 | 2023 |
