| RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia J Zuber, J Shi, E Wang, AR Rappaport, H Herrmann, EA Sison, D Magoon, ... Nature 478 (7370), 524-528, 2011 | 2141 | 2011 |
| R-2HG exhibits anti-tumor activity by targeting FTO/m6A/MYC/CEBPA signaling R Su, L Dong, C Li, S Nachtergaele, M Wunderlich, Y Qing, X Deng, ... Cell 172 (1), 90-105. e23, 2018 | 917 | 2018 |
| METTL14 inhibits hematopoietic stem/progenitor differentiation and promotes leukemogenesis via mRNA m6A modification H Weng, H Huang, H Wu, X Qin, BS Zhao, L Dong, H Shi, J Skibbe, ... Cell stem cell 22 (2), 191-205. e9, 2018 | 855 | 2018 |
| Small-molecule targeting of oncogenic FTO demethylase in acute myeloid leukemia Y Huang, R Su, Y Sheng, L Dong, Z Dong, H Xu, T Ni, ZS Zhang, T Zhang, ... Cancer cell 35 (4), 677-691. e10, 2019 | 650 | 2019 |
| Targeting FTO suppresses cancer stem cell maintenance and immune evasion R Su, L Dong, Y Li, M Gao, L Han, M Wunderlich, X Deng, H Li, Y Huang, ... Cancer cell 38 (1), 79-96. e11, 2020 | 518 | 2020 |
| AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3 M Wunderlich, FS Chou, KA Link, B Mizukawa, RL Perry, M Carroll, ... Leukemia 24 (10), 1785-1788, 2010 | 455 | 2010 |
| Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia J Wei, M Wunderlich, C Fox, S Alvarez, JC Cigudosa, JS Wilhelm, ... Cancer cell 13 (6), 483-495, 2008 | 388 | 2008 |
| PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells P Neviani, JG Harb, JJ Oaks, R Santhanam, CJ Walker, JJ Ellis, ... The Journal of clinical investigation 123 (10), 4144-4157, 2013 | 265 | 2013 |
| Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia S Mi, Z Li, P Chen, C He, D Cao, A Elkahloun, J Lu, LA Pelloso, ... Proceedings of the National Academy of Sciences 107 (8), 3710-3715, 2010 | 250* | 2010 |
| TET1 plays an essential oncogenic role in MLL-rearranged leukemia H Huang, X Jiang, Z Li, Y Li, CX Song, C He, M Sun, P Chen, S Gurbuxani, ... Proceedings of the National Academy of Sciences 110 (29), 11994-11999, 2013 | 238 | 2013 |
| Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells S Goyama, J Schibler, L Cunningham, Y Zhang, Y Rao, N Nishimoto, ... The Journal of clinical investigation 123 (9), 3876-3888, 2013 | 228 | 2013 |
| Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome GW Rhyasen, L Bolanos, J Fang, A Jerez, M Wunderlich, C Rigolino, ... Cancer cell 24 (1), 90-104, 2013 | 213 | 2013 |
| miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia Z Li, H Huang, P Chen, M He, Y Li, S Arnovitz, X Jiang, C He, E Hyjek, ... Nature communications 3 (1), 1-12, 2012 | 190 | 2012 |
| Xenograft models for normal and malignant stem cells S Goyama, M Wunderlich, JC Mulloy Blood, The Journal of the American Society of Hematology 125 (17), 2630-2640, 2015 | 149 | 2015 |
| MLL-rearranged acute lymphoblastic leukemias activate BCL-2 through H3K79 methylation and are sensitive to the BCL-2-specific antagonist ABT-199 JM Benito, L Godfrey, K Kojima, L Hogdal, M Wunderlich, H Geng, I Marzo, ... Cell reports 13 (12), 2715-2727, 2015 | 144 | 2015 |
| MiR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia X Jiang, H Huang, Z Li, C He, Y Li, P Chen, S Gurbuxani, S Arnovitz, ... Proceedings of the National Academy of Sciences 109 (47), 19397-19402, 2012 | 142 | 2012 |
| AML cells are differentially sensitive to chemotherapy treatment in a human xenograft model M Wunderlich, B Mizukawa, FS Chou, C Sexton, M Shrestha, ... Blood, The Journal of the American Society of Hematology 121 (12), e90-e97, 2013 | 140 | 2013 |
| Asymmetrically segregated mitochondria provide cellular memory of hematopoietic stem cell replicative history and drive HSC attrition A Hinge, J He, J Bartram, J Javier, J Xu, E Fjellman, H Sesaki, T Li, J Yu, ... Cell stem cell 26 (3), 420-430. e6, 2020 | 139 | 2020 |
| Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1 J Fang, G Rhyasen, L Bolanos, C Rasch, M Varney, M Wunderlich, ... Blood, The Journal of the American Society of Hematology 120 (4), 858-867, 2012 | 129 | 2012 |
| Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia H Ågerstam, C Karlsson, N Hansen, C Sandén, M Askmyr, S von Palffy, ... Proceedings of the National Academy of Sciences 112 (34), 10786-10791, 2015 | 128 | 2015 |
