Homozygous might be hemizygous: CRISPR/Cas9 editing in iPSCs results in detrimental on-target defects that escape standard quality controls D Simkin, V Papakis, BI Bustos, CM Ambrosi, SJ Ryan, V Baru, ... Stem Cell Reports 17 (4), 993-1008, 2022 | 45 | 2022 |
Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons Z Álvarez, JA Ortega, K Sato, IR Sasselli, AN Kolberg-Edelbrock, R Qiu, ... Cell stem cell 30 (2), 219-238. e14, 2023 | 35 | 2023 |
Uncoupling gene expression noise along the central dogma using genome engineered human cell lines T Quarton, T Kang, V Papakis, K Nguyen, C Nowak, Y Li, L Bleris Nucleic acids research 48 (16), 9406-9413, 2020 | 26 | 2020 |
Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import JR Mann, ED McKenna, D Mawrie, V Papakis, F Alessandrini, ... Science Advances 9 (33), eadi5548, 2023 | 11 | 2023 |
CRISPRi-based screen of Autism Spectrum Disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and uptake of synaptic material OM Teter, NM Draeger, SM Sattler, A McQuade, BB Holmes, V Papakis, ... bioRxiv, 2024.06. 01.596962, 2024 | | 2024 |
PROBING TRANSCRIPTIONAL AND POST-TRANSCRIPTIONAL NOISE USING GENOME INTEGRATED ENGINEERED GENE CIRCUITS T Quarton, V Papakis, Y Li, K Nguyen, L Bleris UNRAVELING THE OPERATIONAL LANDSCAPE OF ENGINEERED GENETIC REGULATORY …, 2019 | | 2019 |