Single-cell transcriptome analysis reveals dynamic cell populations and differential gene expression patterns in control and aneurysmal human aortic tissue Y Li, P Ren, A Dawson, HG Vasquez, W Ageedi, C Zhang, W Luo, R Chen, ... Circulation 142 (14), 1374-1388, 2020 | 186 | 2020 |
Critical role of cytosolic DNA and its sensing adaptor STING in aortic degeneration, dissection, and rupture W Luo, Y Wang, L Zhang, P Ren, C Zhang, Y Li, AR Azares, M Zhang, ... Circulation 141 (1), 42-66, 2020 | 166 | 2020 |
Effect of ciprofloxacin on susceptibility to aortic dissection and rupture in mice SA LeMaire, L Zhang, W Luo, P Ren, AR Azares, Y Wang, C Zhang, ... JAMA surgery 153 (9), e181804-e181804, 2018 | 100 | 2018 |
Astragaloside IV alleviates heart failure via activating PPARα to switch glycolysis to fatty acid β-oxidation Z Dong, P Zhao, M Xu, C Zhang, W Guo, H Chen, J Tian, H Wei, R Lu, ... Scientific reports 7 (1), 2691, 2017 | 92 | 2017 |
Targeting the nlrp 3 inflammasome with inhibitor mcc 950 prevents aortic aneurysms and dissections in mice P Ren, D Wu, R Appel, L Zhang, C Zhang, W Luo, AAB Robertson, ... Journal of the American Heart Association 9 (7), e014044, 2020 | 79 | 2020 |
Critical role of ADAMTS-4 in the development of sporadic aortic aneurysm and dissection in mice P Ren, M Hughes, S Krishnamoorthy, S Zou, L Zhang, D Wu, C Zhang, ... Scientific reports 7 (1), 12351, 2017 | 71 | 2017 |
Stachydrine protects against pressure overload-induced cardiac hypertrophy by suppressing autophagy TT Cao, HH Chen, Z Dong, YW Xu, P Zhao, W Guo, HC Wei, C Zhang, ... Cellular Physiology and Biochemistry 42 (1), 103-114, 2017 | 52 | 2017 |
Role of STIM1 (stromal interaction molecule 1) in hypertrophy-related contractile dysfunction CD Troupes, M Wallner, G Borghetti, C Zhang, S Mohsin, D von Lewinski, ... Circulation research 121 (2), 125-136, 2017 | 48 | 2017 |
Programmed cell death in aortic aneurysm and dissection: a potential therapeutic target A Chakraborty, Y Li, C Zhang, Y Li, SA LeMaire, YH Shen Journal of molecular and cellular cardiology 163, 67-80, 2022 | 47 | 2022 |
Cardiomyocyte PKA ablation enhances basal contractility while eliminates cardiac β-adrenergic response without adverse effects on the heart Y Zhang, WE Wang, X Zhang, Y Li, B Chen, C Liu, X Ai, X Zhang, Y Tian, ... Circulation Research 124 (12), 1760-1777, 2019 | 45 | 2019 |
Exome-wide evaluation of rare coding variants using electronic health records identifies new gene–phenotype associations J Park, AM Lucas, X Zhang, K Chaudhary, JH Cho, G Nadkarni, A Dobbyn, ... Nature medicine 27 (1), 66-72, 2021 | 42 | 2021 |
Single-cell analysis of aneurysmal aortic tissue in patients with Marfan syndrome reveals dysfunctional TGF-β signaling A Dawson, Y Li, Y Li, P Ren, HG Vasquez, C Zhang, KR Rebello, ... Genes 13 (1), 95, 2021 | 29 | 2021 |
Second heart field–derived cells contribute to angiotensin II–mediated ascending aortopathies H Sawada, Y Katsumata, H Higashi, C Zhang, Y Li, S Morgan, LH Lee, ... Circulation 145 (13), 987-1001, 2022 | 25 | 2022 |
Increasing T‐type calcium channel activity by β‐adrenergic stimulation contributes to β‐adrenergic regulation of heart rates Y Li, X Zhang, C Zhang, X Zhang, Y Li, Z Qi, C Szeto, M Tang, Y Peng, ... The Journal of physiology 596 (7), 1137-1151, 2018 | 23 | 2018 |
Caveolae-localized L-type Ca2+ channels do not contribute to function or hypertrophic signalling in the mouse heart RN Correll, CA Makarewich, H Zhang, C Zhang, MA Sargent, AJ York, ... Cardiovascular research 113 (7), 749-759, 2017 | 22 | 2017 |
Epigenetic induction of smooth muscle cell phenotypic alterations in aortic aneurysms and dissections A Chakraborty, Y Li, C Zhang, Y Li, KR Rebello, S Li, S Xu, HG Vasquez, ... Circulation 148 (12), 959-977, 2023 | 20 | 2023 |
Preventing cholesterol-induced perk (protein kinase RNA-like endoplasmic reticulum kinase) signaling in smooth muscle cells blocks atherosclerotic plaque formation A Chattopadhyay, P Guan, S Majumder, K Kaw, Z Zhou, C Zhang, ... Arteriosclerosis, thrombosis, and vascular biology 42 (8), 1005-1022, 2022 | 16 | 2022 |
Remodeling of repolarization and arrhythmia susceptibility in a myosin-binding protein C knockout mouse model A Toib, C Zhang, G Borghetti, X Zhang, M Wallner, Y Yang, CD Troupes, ... American Journal of Physiology-Heart and Circulatory Physiology 313 (3 …, 2017 | 11 | 2017 |
Smooth muscle α-actin missense variant promotes atherosclerosis through modulation of intracellular cholesterol in smooth muscle cells K Kaw, A Chattopadhyay, P Guan, J Chen, S Majumder, X Duan, S Ma, ... European Heart Journal 44 (29), 2713-2726, 2023 | 10 | 2023 |
Aortic stress activates an adaptive program in thoracic aortic smooth muscle cells that maintains aortic strength and protects against aneurysm and dissection in mice C Zhang, Y Li, A Chakraborty, Y Li, KR Rebello, P Ren, W Luo, L Zhang, ... Arteriosclerosis, thrombosis, and vascular biology 43 (2), 234-252, 2023 | 10 | 2023 |