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yang lu
yang lu
在 zju.edu.cn 的电子邮件经过验证
标题
引用次数
引用次数
年份
Development of differentiation modulators and targeted agents for treating neuroblastoma
Z Jin, Y Lu, Y Wu, J Che, X Dong
European Journal of Medicinal Chemistry 207, 112818, 2020
252020
Discovery of N-((3S,4S)-4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl-1H-pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That …
J Che, X Dai, J Gao, H Sheng, W Zhan, Y Lu, D Li, Z Gao, Z Jin, B Chen, ...
Journal of Medicinal Chemistry 64 (16), 12163-12180, 2021
182021
TransFoxMol: predicting molecular property with focused attention
J Gao, Z Shen, Y Xie, J Lu, Y Lu, S Chen, Q Bian, Y Guo, L Shen, J Wu, ...
Briefings in Bioinformatics 24 (5), bbad306, 2023
162023
Design, synthesis and biological evaluation of new dihydropyridine derivatives as PD-L1 degraders for enhancing antitumor immunity
C Pan, M Luo, Y Lu, X Pan, X Chen, L Ding, J Che, Q He, X Dong
Bioorganic Chemistry 125, 105820, 2022
122022
Design, synthesis and biological evaluation of quinazoline derivatives as potent and selective FGFR4 inhibitors
C Pan, W Nie, J Wang, J Du, Z Pan, J Gao, Y Lu, J Che, H Zhu, H Dai, ...
European journal of medicinal chemistry 225, 113794, 2021
102021
Recent progress and applications of small molecule inhibitors of Keap1–Nrf2 axis for neurodegenerative diseases
J Wang, Y Cao, Y Lu, H Zhu, J Zhang, J Che, R Zhuang, J Shao
European Journal of Medicinal Chemistry, 115998, 2023
82023
Design, synthesis, and biological evaluation of quinazoline derivatives with covalent reversible warheads as potential FGFR4 inhibitors
W Nie, Y Lu, C Pan, J Gao, M Luo, J Du, J Wang, P Luo, H Zhu, J Che, ...
Bioorganic chemistry 121, 105673, 2022
82022
Design, synthesis and biological evaluation of sulfonamides inhibitors of XPO1 displaying activity against multiple myeloma cells
B Qu, Y Xu, Y Lu, W Zhuang, X Jin, Q Shi, S Yan, Y Guo, Z Shen, J Che, ...
European Journal of Medicinal Chemistry 235, 114257, 2022
72022
Rational Identification of Novel Antibody‐Drug Conjugate with High Bystander Killing Effect against Heterogeneous Tumors
Y Guo, Z Shen, W Zhao, J Lu, Y Song, L Shen, Y Lu, M Wu, Q Shi, ...
Advanced Science 11 (13), 2306309, 2024
32024
Discovery of N-(1-(6-Oxo-1,6-dihydropyrimidine)-pyrazole) Acetamide Derivatives as Novel Noncovalent DprE1 Inhibitors against Mycobacterium tuberculosis
L Yang, X Hu, Y Lu, R Xu, Y Xu, WL Ma, MS Alam, T Zhang, X Chai, Y Lei, ...
Journal of Medicinal Chemistry 67 (3), 1914-1931, 2024
32024
An updated patent review of AKT inhibitors (2020–present)
L Li, Y Guo, Y Lu, Y Xu, Y Lu, X Zhu, X Dong, J Che
Expert Opinion on Therapeutic Patents 33 (9), 549-564, 2023
22023
Cpd-A1 alleviates acute kidney injury by inhibiting ferroptosis
Y Chen, M Wu, M Xie, Y Lu, C Li, S Xie, W Ma, M Ji, R Hou, Z Dong, R He, ...
Acta Pharmacologica Sinica, 1-13, 2024
12024
Injectable and Sprayable Fluorescent Nanoprobe for Rapid Real‐Time Detection of Human Colorectal Tumors
B Zhang, J Lu, X Lin, J Wang, Q Li, T Jin, Q Shi, Y Lu, J Zhang, J Deng, ...
Advanced Materials, 2405275, 0
1
Discovery of New Phenyltetrazolium Derivatives as Ferroptosis Inhibitors for Treating Ischemic Stroke: An Example Development from Free Radical Scavengers
Y Lu, Z Shen, Y Xu, H Lin, L Shen, Y Jin, Y Guo, J Lu, L Li, Y Zhuang, ...
Journal of Medicinal Chemistry 67 (14), 11712-11731, 2024
2024
Discovery of a Highly Potent and Selective BRD9 PROTAC Degrader Based on E3 Binder Investigation for the Treatment of Hematological Tumors
H Duan, J Zhang, R Gui, Y Lu, A Pang, B Chen, L Shen, H Yu, J Li, T Xu, ...
Journal of Medicinal Chemistry 67 (13), 11326-11353, 2024
2024
Discovery of potent small molecule ubiquitin-specific protease 10 inhibitors with anti-hepatocellular carcinoma activity through regulating YAP expression
Y Lu, J Gao, P Wang, H Chen, X He, M Luo, Y Guo, L Li, W Zhuang, ...
European Journal of Medicinal Chemistry 272, 116468, 2024
2024
Discovery of Orally Bioavailable Phenyltetrazolium Derivatives for the Acute Treatment and the Secondary Prevention of Ischemic Stroke
Y Lu, H Lin, Y Xu, Z Shen, Y Guo, Y Jin, Q Shi, H Chen, Y Zhuang, ...
European Journal of Medicinal Chemistry, 116542, 2024
2024
Targeted delivery of cathepsin-activatable near-infrared fluorescence probe for ultrahigh specific imaging of peritoneal metastasis
J Lu, Y Guo, H Hao, J Ma, Y Lu, Y Sun, Z Shi, X Dong, B Zhang, L Fang, ...
European Journal of Medicinal Chemistry 262, 115909, 2023
2023
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