NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity T Moriyama, R Nishii, V Perez-Andreu, W Yang, FA Klussmann, X Zhao, ... Nature genetics 48 (4), 367-373, 2016 | 477 | 2016 |
Massively parallel variant characterization identifies NUDT15 alleles associated with thiopurine toxicity CC Suiter, T Moriyama, KA Matreyek, W Yang, ER Scaletti, R Nishii, ... Proceedings of the National Academy of Sciences 117 (10), 5394-5401, 2020 | 108 | 2020 |
Clinical Pharmacogenetics Implementation Consortium Guideline for the Use of Aminoglycosides Based on MT‐RNR1 Genotype JH McDermott, J Wolf, K Hoshitsuki, R Huddart, KE Caudle, ... Clinical Pharmacology & Therapeutics 111 (2), 366-372, 2022 | 64 | 2022 |
Molecular basis of ETV6-mediated predisposition to childhood acute lymphoblastic leukemia R Nishii, R Baskin-Doerfler, W Yang, N Oak, X Zhao, W Yang, ... Blood, The Journal of the American Society of Hematology 137 (3), 364-373, 2021 | 53 | 2021 |
Glibenclamide produces region-dependent effects on cerebral edema in a combined injury model of traumatic brain injury and hemorrhagic shock in mice RM Jha, BJ Molyneaux, TC Jackson, JS Wallisch, SY Park, S Poloyac, ... Journal of neurotrauma 35 (17), 2125-2135, 2018 | 42 | 2018 |
Amino acid metabolic vulnerabilities in acute and chronic myeloid leukemias A Bhingarkar, HV Vangapandu, S Rathod, K Hoshitsuki, CA Fernandez Frontiers in Oncology 11, 694526, 2021 | 11 | 2021 |
Challenges in clinical implementation of CYP2D6 genotyping: choice of variants to test affects phenotype determination K Hoshitsuki, KR Crews, W Yang, CA Smith, JS Hankins, AJ Turner, ... Genetics in medicine 22 (1), 232-233, 2020 | 11 | 2020 |
Medication use as a contributor to fluid overload in the PICU: a prospective observational study D Fuhrman, K Crowley, C Vetterly, K Hoshitsuki, A Koval, J Carcillo Journal of Pediatric Intensive Care 7 (02), 069-074, 2018 | 10 | 2018 |
Rituximab administration in pediatric patients with newly diagnosed acute lymphoblastic leukemia K Hoshitsuki, Y Zhou, AM Miller, JK Choi, HD Swanson, NH Bhakta, ... Leukemia 37 (9), 1782-1791, 2023 | 8 | 2023 |
Pharmacogenomics for drug dosing in children: Current use, knowledge, and gaps K Hoshitsuki, CA Fernandez, JJ Yang The Journal of Clinical Pharmacology 61, S188-S192, 2021 | 8 | 2021 |
Association of inherited genetic factors with drug-induced hepatic damage among children with acute lymphoblastic leukemia W Yang, SE Karol, K Hoshitsuki, S Lee, EC Larsen, N Winick, WL Carroll, ... JAMA Network Open 5 (12), e2248803-e2248803, 2022 | 7 | 2022 |
Long‐read HiFi sequencing of NUDT15: Phased full‐gene haplotyping and pharmacogenomic allele discovery ER Scott, Y Yang, MR Botton, Y Seki, K Hoshitsuki, J Harting, P Baybayan, ... Human mutation 43 (11), 1557-1566, 2022 | 5 | 2022 |
Mechanistic studies of PEG-asparaginase-induced liver injury and hepatic steatosis in mice GVN Kumar, K Hoshitsuki, S Rathod, MJ Ramsey, L Kokai, EE Kershaw, ... Acta Pharmaceutica Sinica B 11 (12), 3779-3790, 2021 | 5 | 2021 |
EVALUATION OF GLIBENCLAMIDE IN THE PITTSBURGH CONTROLLED CORTICAL IMPACT MODEL OF TRAU-MATIC BRAIN INJURY: AN OBTT CONSORTIUM STUDY R Jha, H Yan, CE Dixon, S Poloyac, T Jackson, K Hoshitsuki, X Ma, ... EVALUATION 8, 17, 2015 | 5 | 2015 |
Adalimumab immunogenicity is negatively correlated with anti-hinge antibody levels in patients with rheumatoid arthritis K Hoshitsuki, S Rathod, MJ Ramsey, L Zhu, LW Moreland, CA Fernandez Journal of Pharmacology and Experimental Therapeutics 375 (3), 488-497, 2020 | 3 | 2020 |
Metabolic Acidosis in a pediatric patient with leukemia and fungal infection K Hoshitsuki, AR Molinelli, H Inaba, JE Rubnitz, PJ Barker Clinical Chemistry 66 (4), 518-522, 2020 | 3 | 2020 |
Comprehensive functional characterization of germline ETV6 variants associated with inherited predisposition to acute lymphoblastic leukemia in children R Nishii, R Baskin, T Moriyama, K Hoshitsuki, ML Metzger, G Wu, ... Blood 128 (22), 1085, 2016 | 3 | 2016 |
Additive effects of TPMT and NUDT15 on thiopurine toxicity in children with acute lymphoblastic leukemia across multiethnic populations M Maillard, R Nishii, W Yang, K Hoshitsuki, D Chepyala, SHR Lee, ... JNCI: Journal of the National Cancer Institute 116 (5), 702-710, 2024 | 1 | 2024 |
Functional analysis of germline ETV6 variants associated with familial thrombocytopenia and acute lymphoblastic leukemia R Baskin, R Nishii, J Nadaf, K Verbist, P Tedrick, K Hoshitsuki, M Qian, ... Experimental Hematology 53, S126-S127, 2017 | 1 | 2017 |
Investigation of immunologic and hepatic adverse effects of asparaginase K Hoshitsuki University of Pittsburgh, 2024 | | 2024 |