RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V (D) J rearrangement Y Shinkai, KP Lam, EM Oltz, V Stewart, M Mendelsohn, J Charron, ... Cell 68 (5), 855-867, 1992 | 3424 | 1992 |
In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death KP Lam, R Kühn, K Rajewsky Cell 90 (6), 1073-1083, 1997 | 1432 | 1997 |
TACI and BAFF-R mediate isotype switching in B cells E Castigli, SA Wilson, S Scott, F Dedeoglu, S Xu, KP Lam, RJ Bram, ... The Journal of experimental medicine 201 (1), 35-39, 2005 | 677 | 2005 |
Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL MJ Benson, SR Dillon, E Castigli, RS Geha, S Xu, KP Lam, RJ Noelle The Journal of Immunology 180 (6), 3655-3659, 2008 | 525 | 2008 |
Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA DI Yu, AHM Tan, X Hu, V Athanasopoulos, N Simpson, DG Silva, A Hutloff, ... Nature 450 (7167), 299-303, 2007 | 480 | 2007 |
Memory B-cell persistence is independent of persisting immunizing antigen M Maruyama, KP Lam, K Rajewsky Nature 407 (6804), 636-642, 2000 | 451 | 2000 |
B-cell maturation protein, which binds the tumor necrosis factor family members BAFF and APRIL, is dispensable for humoral immune responses S Xu, KP Lam Molecular and Cellular Biology 21 (12), 4067-4074, 2001 | 373 | 2001 |
RIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infection AMA Nasirudeen, HH Wong, P Thien, S Xu, KP Lam, DX Liu PLoS neglected tropical diseases 5 (1), e926, 2011 | 369 | 2011 |
ICOS controls the pool size of effector-memory and regulatory T cells Y Burmeister, T Lischke, AC Dahler, HW Mages, KP Lam, AJ Coyle, ... The Journal of Immunology 180 (2), 774-782, 2008 | 334 | 2008 |
B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity LI Pao, KP Lam, JM Henderson, JL Kutok, M Alimzhanov, L Nitschke, ... Immunity 27 (1), 35-48, 2007 | 313 | 2007 |
B cell antigen receptor specificity and surface density together determine B-1 versus B-2 cell development KP Lam, K Rajewsky The Journal of experimental medicine 190 (4), 471-478, 1999 | 276 | 1999 |
Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma HL Penny, JL Sieow, G Adriani, WH Yeap, P See Chi Ee, B San Luis, ... Oncoimmunology 5 (8), e1191731, 2016 | 227 | 2016 |
Single-cell atlas of lineage states, tumor microenvironment, and subtype-specific expression programs in gastric cancer V Kumar, K Ramnarayanan, R Sundar, N Padmanabhan, S Srivastava, ... Cancer discovery 12 (3), 670-691, 2022 | 211 | 2022 |
Macrophage polarization to a unique phenotype driven by B cells SC Wong, AL Puaux, M Chittezhath, I Shalova, TS Kajiji, X Wang, ... European journal of immunology 40 (8), 2296-2307, 2010 | 211 | 2010 |
Basal immunoglobulin signaling actively maintains developmental stage in immature B cells LE Tze, BR Schram, KP Lam, KA Hogquist, KL Hippen, J Liu, SA Shinton, ... PLoS biology 3 (3), e82, 2005 | 196 | 2005 |
Phospholipase Cγ2 is critical for Dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells S Xu, J Huo, KG Lee, T Kurosaki, KP Lam Journal of Biological Chemistry 284 (11), 7038-7046, 2009 | 195 | 2009 |
B cell development and activation defects resulting in xid-like immunodeficiency in BLNK/SLP-65-deficient mice S Xu, JEL Tan, EPY Wong, A Manickam, S Ponniah, KP Lam International immunology 12 (3), 397-404, 2000 | 164 | 2000 |
Bruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral response KG Lee, S Xu, ZH Kang, J Huo, M Huang, D Liu, O Takeuchi, S Akira, ... Proceedings of the National Academy of Sciences 109 (15), 5791-5796, 2012 | 163 | 2012 |
B-1 cells: unique origins and functions AM Stall, SM Wells, KP Lam Seminars in immunology 8 (1), 45-59, 1996 | 161 | 1996 |
A conformational change in cytochrome c of apoptotic and necrotic cells is detected by monoclonal antibody binding and mimicked by association of the native antigen with … R Jemmerson, J Liu, D Hausauer, KP Lam, A Mondino, RD Nelson Biochemistry 38 (12), 3599-3609, 1999 | 148 | 1999 |