| Tunneling nanotubes and gap junctions–their role in long-range intercellular communication during development, health, and disease conditions J Ariazi, A Benowitz, V De Biasi, ML Den Boer, S Cherqui, H Cui, ... Frontiers in molecular neuroscience 10, 333, 2017 | 220 | 2017 |
| Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2 A Mares, AH Miah, IED Smith, M Rackham, AR Thawani, J Cryan, ... Communications biology 3 (1), 140, 2020 | 172 | 2020 |
| Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia MB Pappalardi, K Keenan, M Cockerill, WA Kellner, A Stowell, C Sherk, ... Nature cancer 2 (10), 1002-1017, 2021 | 163 | 2021 |
| The PROTACtable genome M Schneider, CJ Radoux, A Hercules, D Ochoa, I Dunham, LP Zalmas, ... Nature reviews Drug discovery 20 (10), 789-797, 2021 | 162 | 2021 |
| Stereochemistry of the core structure of the mycolactones AB Benowitz, S Fidanze, PLC Small, Y Kishi Journal of the American Chemical Society 123 (21), 5128-5129, 2001 | 107 | 2001 |
| Total synthesis of the mycolactones F Song, S Fidanze, AB Benowitz, Y Kishi Organic letters 4 (4), 647-650, 2002 | 82 | 2002 |
| Discovery and characterisation of highly cooperative FAK‐degrading PROTACs RP Law, J Nunes, C Chung, M Bantscheff, K Buda, H Dai, JP Evans, ... Angewandte Chemie International Edition 60 (43), 23327-23334, 2021 | 80 | 2021 |
| Structural insights into PROTAC-mediated degradation of Bcl-xL C Chung, H Dai, E Fernandez, CP Tinworth, I Churcher, J Cryan, ... ACS Chemical Biology 15 (9), 2316-2323, 2020 | 68 | 2020 |
| Design and synthesis of a competent pyrrolinone− peptide hybrid ligand for the class II major histocompatibility complex protein HLA-DR1 AB Smith, AB Benowitz, PA Sprengeler, J Barbosa, MC Guzman, ... Journal of the American Chemical Society 121 (40), 9286-9298, 1999 | 55 | 1999 |
| Selective CDK6 degradation mediated by cereblon, VHL, and novel IAP-recruiting PROTACs NA Anderson, J Cryan, A Ahmed, H Dai, GA McGonagle, C Rozier, ... Bioorganic & Medicinal Chemistry Letters 30 (9), 127106, 2020 | 49 | 2020 |
| In vitro and in vivo induction of fetal hemoglobin with a reversible and selective DNMT1 inhibitor AG Gilmartin, A Groy, ER Gore, C Atkins, ER Long, MN Montoute, Z Wu, ... Haematologica 106 (7), 1979, 2021 | 48 | 2021 |
| Total synthesis of mycolactones A and B F Song, S Fidanze, AB Benowitz, Y Kishi Tetrahedron 63 (26), 5739-5753, 2007 | 43 | 2007 |
| A second-generation synthesis of scalemic 3, 5, 5-trisubstituted pyrrolin-4-ones: Incorporation of functionalized amino acid side-chains AB Smith III, AB Benowitz, DA Favor, PA Sprengeler, R Hirschmann Tetrahedron letters 38 (22), 3809-3812, 1997 | 39 | 1997 |
| Discovery and characterization of a class of pyrazole inhibitors of bacterial undecaprenyl pyrophosphate synthase N Concha, J Huang, X Bai, A Benowitz, P Brady, LSC Grady, LH Kryn, ... Journal of Medicinal Chemistry 59 (15), 7299-7304, 2016 | 37 | 2016 |
| Design, Synthesis, and Evaluation of a Pyrrolinone− Peptide Hybrid Ligand for the Class II MHC Protein HLA-DR1 AB Smith, AB Benowitz, MC Guzman, PA Sprengeler, R Hirschmann, ... Journal of the American Chemical Society 120 (48), 12704-12705, 1998 | 34 | 1998 |
| The therapeutic potential of PROTACs AB Benowitz, KL Jones, JD Harling Expert Opinion on Therapeutic Patents 31 (1), 1-24, 2021 | 31 | 2021 |
| Fragment-based discovery of 6-azaindazoles as inhibitors of bacterial DNA ligase S Howard, N Amin, AB Benowitz, E Chiarparin, H Cui, X Deng, ... ACS Medicinal Chemistry Letters 4 (12), 1208-1212, 2013 | 30 | 2013 |
| Design, synthesis, and binding affinities of pyrrolinone-based somatostatin mimetics AB Smith, AK Charnley, EF Mesaros, O Kikuchi, W Wang, A Benowitz, ... Organic Letters 7 (3), 399-402, 2005 | 30 | 2005 |
| Peptide deformylase inhibitors D Qin, B Norton, X Liao, AN Knox, Y Fang, J Lee, JC Dreabit, ... | 23 | 2009 |
| The crystal structure of a pyrrolinone− peptide hybrid ligand bound to the human class II MHC protein HLA-DR1 KH Lee, GL Olson, DR Bolin, AB Benowitz, PA Sprengeler, AB Smith, ... Journal of the American Chemical Society 122 (35), 8370-8375, 2000 | 22 | 2000 |
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