Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis S Camelo, AH Iglesias, D Hwang, B Due, H Ryu, K Smith, SG Gray, ... Journal of neuroimmunology 164 (1-2), 10-21, 2005 | 329 | 2005 |
Vaccine-induced control of viral shedding following rhesus cytomegalovirus challenge in rhesus macaques K Abel, J Martinez, Y Yue, SF Lacey, Z Wang, L Strelow, A Dasgupta, Z Li, ... Journal of virology 85 (6), 2878-2890, 2011 | 59 | 2011 |
In vivo overexpression of frataxin causes toxicity mediated by iron-sulfur cluster deficiency C Huichalaf, TL Perfitt, A Kuperman, R Gooch, RC Kovi, KA Brenneman, ... Molecular Therapy-Methods & Clinical Development 24, 367-378, 2022 | 32 | 2022 |
Considerations for preclinical safety assessment of adeno-associated virus gene therapy products BT Assaf, LO Whiteley Toxicologic Pathology 46 (8), 1020-1027, 2018 | 27 | 2018 |
Limited dissemination and shedding of the UL128 complex-intact, UL/b′-defective rhesus cytomegalovirus strain 180.92 BT Assaf, KG Mansfield, L Strelow, SV Westmoreland, PA Barry, A Kaur Journal of virology 88 (16), 9310-9320, 2014 | 27 | 2014 |
Patterns of acute rhesus cytomegalovirus (RhCMV) infection predict long-term RhCMV infection BT Assaf, KG Mansfield, SV Westmoreland, A Kaur, KL Oxford, ... Journal of virology 86 (11), 6354-6357, 2012 | 23 | 2012 |
Pleural Endometriosis in an Aged Rhesus Macaque (Macaca mulatta) A Histopathologic and Immunohistochemical Study BT Assaf, AD Miller Veterinary pathology 49 (4), 636-641, 2012 | 22 | 2012 |
Live-attenuated lentivirus immunization modulates innate immunity and inflammation while protecting rhesus macaques from vaginal simian immunodeficiency virus challenge M Genesca, ZM Ma, Y Wang, B Assaf, H Qureshi, L Fritts, Y Huang, ... Journal of virology 86 (17), 9188-9200, 2012 | 19 | 2012 |
Scientific and Regulatory Policy Committee points to consider: nonclinical research and development of in vivo gene therapy products, emphasizing adeno-associated virus vectors JA Hutt, BT Assaf, B Bolon, J Cavagnaro, E Galbreath, B Grubor, ... Toxicologic Pathology 50 (1), 118-146, 2022 | 18 | 2022 |
Preclinical biosafety evaluation of cell-based therapies: emerging global paradigms J Basu, BT Assaf, TA Bertram, M Rao Toxicologic Pathology 43 (1), 115-125, 2015 | 17 | 2015 |
Meeting report: spontaneous lesions and diseases in wild, captive-bred, and zoo-housed nonhuman primates and in nonhuman primate species used in drug safety studies VG Sasseville, KG Mansfield, JL Mankowski, C Tremblay, KA Terio, ... Veterinary pathology 49 (6), 1057-1069, 2012 | 15 | 2012 |
Rhesus Cytomegalovirus (Macacine Herpesvirus 3)–Associated Facial Neuritis in Simian Immunodeficiency Virus–Infected Rhesus Macaques (Macaca mulatta) BT Assaf, HL Knight, AD Miller Veterinary pathology 52 (1), 217-223, 2015 | 12 | 2015 |
Growth-associated protein-43 and ephrin B3 induction in the brain of adult SIV-infected rhesus macaques SV Westmoreland, L Annamalai, MR Lentz, EM Ratai, B Assaf, K Boisvert, ... Journal of neurovirology 17, 455-468, 2011 | 6 | 2011 |
Scientific and Regulatory Policy Committee technical review: biology and pathology of ganglia in animal species used for nonclinical safety testing BM Bennet, ID Pardo, BT Assaf, E Buza, SD Cramer, LTK Crawford, ... Toxicologic pathology 51 (5), 278-305, 2023 | 4 | 2023 |
Scientific and Regulatory Policy Committee points to consider: sampling, processing, evaluation, interpretation, and reporting of test article-related ganglion pathology for … BM Bennet, ID Pardo, BT Assaf, E Buza, S Cramer, LTK Crawford, ... Toxicologic Pathology 51 (4), 176-204, 2023 | 4 | 2023 |
Cytomegaloviral hypophysitis in a simian immunodeficiency virus‐infected rhesus macaque (Macacca mulatta) MR Berg, MA Owston, MC Gauduin, BT Assaf, AD Lewis, EJ Dick Jr Journal of medical primatology 46 (6), 364-367, 2017 | 4 | 2017 |
Preclinical Study Design for Evaluation of Stem Cell–derived Cellular Therapy Products: A Pathologist’s Perspective JFM Baker, BT Assaf Toxicologic Pathology 43 (1), 126-131, 2015 | 3 | 2015 |
Optimizing MRI-Guided Intra-Striatal AAV Dose Administration in Non-Human Primates J Bu, B Elmer, B Assaf, C Dangler, M Goulet, C Mueller, S Ramachandran MOLECULAR THERAPY 30 (4), 128-128, 2022 | | 2022 |
Development of an AAV-Based microRNA Gene Therapy for Myotonic Dystrophy Type 1 (DM1) NR Kollu, W Fan, J Sullivan, S Cao, J Cao, R Jackson, S Nass, B Nambiar, ... MOLECULAR THERAPY 30 (4), 498-498, 2022 | | 2022 |
New Insights into the Toxicity of AAV-Mediated Overexpression of Frataxin C Huichalaf, TL Perfitt, A Kuperman, R Gooch, RC Kovi, K Brenneman, ... MOLECULAR THERAPY 30 (4), 365-365, 2022 | | 2022 |