| Functional analysis of epidermal growth factor receptor (EGFR) mutations and potential implications for EGFR targeted therapy RK Kancha, N Von Bubnoff, C Peschel, J Duyster Clinical cancer research 15 (2), 460-467, 2009 | 204 | 2009 |
| Differential sensitivity of ERBB2 kinase domain mutations towards lapatinib RK Kancha, N von Bubnoff, N Bartosch, C Peschel, RA Engh, J Duyster PloS one 6 (10), e26760, 2011 | 137 | 2011 |
| Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in non-small cell lung cancer harboring uncommon EGFR mutations: Focus on afatinib A Masood, RK Kancha, J Subramanian Seminars in oncology 46 (3), 271-283, 2019 | 90 | 2019 |
| The systemic mastocytosis-specific activating cKit mutation D816V can be inhibited by the tyrosine kinase inhibitor AMN107 N Von Bubnoff, SHP Gorantla, RK Kancha, F Lordick, C Peschel, ... Leukemia 19 (9), 1670-1671, 2005 | 85 | 2005 |
| Emergence of ERBB2 Mutation as a Biomarker and an Actionable Target in Solid Cancers J Subramanian, A Katta, A Masood, DR Vudem, RK Kancha The oncologist 24 (12), e1303-e1314, 2019 | 77 | 2019 |
| The epidermal growth factor receptor-L861Q mutation increases kinase activity without leading to enhanced sensitivity toward epidermal growth factor receptor kinase inhibitors RK Kancha, C Peschel, J Duyster Journal of thoracic oncology 6 (2), 387-392, 2011 | 69 | 2011 |
| Sensitivity toward sorafenib and sunitinib varies between different activating and drug-resistant FLT3-ITD mutations RK Kancha, R Grundler, C Peschel, J Duyster Experimental hematology 35 (10), 1522-1526, 2007 | 69 | 2007 |
| Activating germline R776H mutation in the epidermal growth factor receptor associated with lung cancer with squamous differentiation J van Noesel, WH van der Ven, TAM van Os, PWA Kunst, J Weegenaar, ... Journal of clinical oncology: official journal of the American Society of …, 2013 | 55 | 2013 |
| Synthesis of novel forskolin isoxazole derivatives with potent anti-cancer activity against breast cancer cell lines S Burra, V Voora, CP Rao, PV Kumar, RK Kancha, GLD Krupadanam Bioorganic & Medicinal Chemistry Letters 27 (18), 4314-4318, 2017 | 45 | 2017 |
| FeCl 3 catalysed 7-membered ring formation in a single pot: a new route to indole-fused oxepines/azepines and their cytotoxic activity KS Kumar, MS Ramulu, B Rajesham, NP Kumar, V Voora, RK Kancha Organic & Biomolecular Chemistry 15 (20), 4468-4476, 2017 | 32 | 2017 |
| Imatinib and leptomycin B are effective in overcoming imatinib-resistance due to Bcr-Abl amplification and clonal evolution but not due to Bcr-Abl kinase domain mutation RK Kancha, N Von Bubnoff, C Miething, C Peschel, KS Götze, J Duyster Haematologica 93 (11), 1718-1722, 2008 | 29 | 2008 |
| Asymmetric kinase dimer formation is crucial for the activation of oncogenic EGFRvIII but not for ERBB3 phosphorylation RK Kancha, N Von Bubnoff, J Duyster Cell communication and signaling 11, 1-7, 2013 | 21 | 2013 |
| Silver-catalyzed synthesis of pyrrolopiperazine fused with oxazine/imidazole via a domino approach: evaluation of anti-cancer activity KS Kumar, NP Kumar, B Rajesham, G Kishan, S Akula, RK Kancha New Journal of Chemistry 42 (1), 34-38, 2018 | 19 | 2018 |
| Targeting oncoprotein stability overcomes drug resistance caused by FLT3 kinase domain mutations C Yu, RK Kancha, J Duyster PLoS One 9 (5), e97116, 2014 | 19 | 2014 |
| Computational analysis of epidermal growth factor receptor mutations predicts differential drug sensitivity profiles toward kinase inhibitors S Akula, S Kamasani, SK Sivan, V Manga, DR Vudem, RK Kancha Journal of Thoracic Oncology 13 (5), 721-726, 2018 | 17 | 2018 |
| Analysis of conformational determinants underlying HSP90-kinase interaction RK Kancha, N Bartosch, J Duyster PLoS One 8 (7), e68394, 2013 | 16 | 2013 |
| Synthesis of pyrazole-substituted chromene analogues with selective anti-leukemic activity G Madhu, M Sudhakar, K Santosh Kumar, G Rajashekher Reddy, ... Russian Journal of General Chemistry 87, 2421-2428, 2017 | 15 | 2017 |
| Synthesis and cytotoxicity of novel 14α-O-(1,4-disubstituted-1,2,3-triazolyl) ester derivatives of andrographolide S Mokenapelli, M Gutam, N Vadiyaala, JR Yerrabelli, S Banerjee, P Roy, ... Natural product research 35 (2), 289-297, 2021 | 13 | 2021 |
| Bis(1H‐indol‐2‐yl)methanones are effective inhibitors of FLT3‐ITD tyrosine kinase and partially overcome resistance to PKC412A in vitro F Heidel, DB Lipka, FK Mirea, S Mahboobi, R Grundler, RK Kancha, ... British journal of haematology 144 (6), 865-874, 2009 | 13 | 2009 |
| Evolvement of nutraceutical onion plants engineered for resveratrol biosynthetic pathway R Naini, P Pavankumar, S Prabhakar, RK Kancha, KV Rao, VD Reddy Plant Cell Reports 38, 1127-1137, 2019 | 10 | 2019 |
