Aire regulates negative selection of organ-specific T cells A Liston, S Lesage, J Wilson, L Peltonen, CC Goodnow Nature immunology 4 (4), 350-354, 2003 | 983 | 2003 |
Novel dimeric Nur77 signaling mechanism in endocrine and lymphoid cells A Philips, S Lesage, R Gingras, MH Maira, Y Gauthier, P Hugo, J Drouin Molecular and cellular biology, 1997 | 432 | 1997 |
Gene Dosage–limiting Role of Aire in Thymic Expression, Clonal Deletion, and Organ-specific Autoimmunity A Liston, DHD Gray, S Lesage, AL Fletcher, J Wilson, KE Webster, ... The Journal of experimental medicine 200 (8), 1015-1026, 2004 | 349 | 2004 |
Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis JE Jun, LE Wilson, CG Vinuesa, S Lesage, M Blery, LA Miosge, MC Cook, ... Immunity 18 (6), 751-762, 2003 | 336 | 2003 |
The importance of dendritic cells in maintaining immune tolerance C Audiger, MJ Rahman, TJ Yun, KV Tarbell, S Lesage The Journal of Immunology 198 (6), 2223-2231, 2017 | 295 | 2017 |
Antagonism between Nur77 and glucocorticoid receptor for control of transcription A Philips, M Maira, A Mullick, M Chamberland, S Lesage, P Hugo, ... Molecular and Cellular Biology 17 (10), 5952-5959, 1997 | 252 | 1997 |
Generalized resistance to thymic deletion in the NOD mouse: a polygenic trait characterized by defective induction of Bim A Liston, S Lesage, DHD Gray, LA O'Reilly, A Strasser, AM Fahrer, ... Immunity 21 (6), 817-830, 2004 | 205 | 2004 |
Failure to censor forbidden clones of CD4 T cells in autoimmune diabetes S Lesage, SB Hartley, S Akkaraju, J Wilson, M Townsend, CC Goodnow The Journal of experimental medicine 196 (9), 1175-1188, 2002 | 182 | 2002 |
Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes J Dooley, L Tian, S Schonefeldt, V Delghingaro-Augusto, JE Garcia-Perez, ... Nature genetics 48 (5), 519-527, 2016 | 141 | 2016 |
Expression of the self‐marker CD47 on dendritic cells governs their trafficking to secondary lymphoid organs VQ Van, S Lesage, S Bouguermouh, P Gautier, M Rubio, M Levesque, ... The EMBO journal 25 (23), 5560-5568, 2006 | 112 | 2006 |
Specific activation of the cysteine protease CPP32 during the negative selection of T cells in the thymus A Alam, MY Braun, F Hartgers, S Lesage, L Cohen, P Hugo, F Denis, ... The Journal of experimental medicine 186 (9), 1503-1512, 1997 | 108 | 1997 |
A comprehensive review of the phenotype and function of antigen-specific immunoregulatory double negative T cells EE Hillhouse, S Lesage Journal of autoimmunity 40, 58-65, 2013 | 107 | 2013 |
CD4+ CD8+ thymocytes are preferentially induced to die following CD45 cross-linking, through a novel apoptotic pathway. S Lesage, AM Steff, F Philippoussis, M Pagé, S Trop, V Mateo, P Hugo Journal of immunology (Baltimore, Md.: 1950) 159 (10), 4762-4771, 1997 | 105 | 1997 |
IL23R (interleukin 23 receptor) variants protective against inflammatory bowel diseases (IBD) display loss of function due to impaired protein stability and intracellular … D Sivanesan, C Beauchamp, C Quinou, J Lee, S Lesage, S Chemtob, ... Journal of Biological Chemistry 291 (16), 8673-8685, 2016 | 93 | 2016 |
Genetic lesions in T‐cell tolerance and thresholds for autoimmunity A Liston, S Lesage, DHD Gray, RL Boyd, CC Goodnow Immunological reviews 204 (1), 87-101, 2005 | 80 | 2005 |
T cell tolerance to a neo-self antigen expressed by thymic epithelial cells: the soluble form is more effective than the membrane-bound form M Zhang, MS Vacchio, BP Vistica, S Lesage, CE Egwuagu, CR Yu, ... The Journal of Immunology 170 (8), 3954-3962, 2003 | 66 | 2003 |
Interleukin‐10 limits the expansion of immunoregulatory CD4−CD8− T cells in autoimmune‐prone non‐obese diabetic mice EE Hillhouse, C Beauchamp, G Chabot‐Roy, V Dugas, S Lesage Immunology and cell biology 88 (8), 771-780, 2010 | 61 | 2010 |
The orphan nuclear receptor NR4A3 controls the differentiation of monocyte-derived dendritic cells following microbial stimulation S Boulet, JF Daudelin, L Odagiu, AN Pelletier, TJ Yun, S Lesage, ... Proceedings of the National Academy of Sciences 116 (30), 15150-15159, 2019 | 59 | 2019 |
Implication of the CD47 pathway in autoimmune diabetes V Dugas, C Beauchamp, G Chabot-Roy, EE Hillhouse, S Lesage Journal of autoimmunity 35 (1), 23-32, 2010 | 57 | 2010 |
LILAC pilot study: effects of metformin on mTOR activation and HIV reservoir persistence during antiretroviral therapy D Planas, A Pagliuzza, R Ponte, A Fert, LR Marchand, M Massanella, ... EBioMedicine 65, 2021 | 55 | 2021 |