Noncanonical inflammasome activation by intracellular LPS independent of TLR4 N Kayagaki, MT Wong, IB Stowe, SR Ramani, LC Gonzalez, ... Science 341 (6151), 1246-1249, 2013 | 1568 | 2013 |
The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells X Yu, K Harden, L C Gonzalez, M Francesco, E Chiang, B Irving, I Tom, ... Nature immunology 10 (1), 48-57, 2009 | 1460 | 2009 |
TREM2 binds to apolipoproteins, including APOE and CLU/APOJ, and thereby facilitates uptake of amyloid-beta by microglia FL Yeh, Y Wang, I Tom, LC Gonzalez, M Sheng Neuron 91 (2), 328-340, 2016 | 824 | 2016 |
IL-17C regulates the innate immune function of epithelial cells in an autocrine manner V Ramirez-Carrozzi, A Sambandam, E Luis, Z Lin, S Jeet, J Lesch, ... Nature immunology 12 (12), 1159-1166, 2011 | 518 | 2011 |
SNARE interactions are not selective: implications for membrane fusion specificity B Yang, L Gonzalez, R Prekeris, M Steegmaier, RJ Advani, RH Scheller Journal of Biological Chemistry 274 (9), 5649-5653, 1999 | 409 | 1999 |
A coreceptor interaction between the CD28 and TNF receptor family members B and T lymphocyte attenuator and herpesvirus entry mediator LC Gonzalez, KM Loyet, J Calemine-Fenaux, V Chauhan, B Wranik, ... Proceedings of the National Academy of Sciences 102 (4), 1116-1121, 2005 | 350 | 2005 |
nSec1 binds a closed conformation of syntaxin1A B Yang, M Steegmaier, LC Gonzalez Jr, RH Scheller The Journal of cell biology 148 (2), 247-252, 2000 | 331 | 2000 |
Buried polar residues and structural specificity in the GCN4 leucine zipper L Gonzalez Jr, DN Woolfson, T Alber Nature structural biology 3 (12), 1011-1018, 1996 | 312 | 1996 |
Attenuating lymphocyte activity: the crystal structure of the BTLA-HVEM complex DM Compaan, LC Gonzalez, I Tom, KM Loyet, D Eaton, SG Hymowitz Journal of Biological Chemistry 280 (47), 39553-39561, 2005 | 225 | 2005 |
Regulation of membrane trafficking: structural insights from a Rab/effector complex L Gonzalez, RH Scheller Cell 96 (6), 755-758, 1999 | 205 | 1999 |
An engineered allosteric switch in leucine-zipper oligomerization L Gonzalez Jr, JJ Plecs, T Alber Nature Structural Biology 3 (6), 510-515, 1996 | 178 | 1996 |
Crystal structures of a single coiled-coil peptide in two oligomeric states reveal the basis for structural polymorphism L Gonzalez Jr, RA Brown, D Richardson, T Alber Nature structural biology 3 (12), 1002-1010, 1996 | 129 | 1996 |
Antibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized mice HD Brightbill, S Jeet, Z Lin, D Yan, M Zhou, M Tan, A Nguyen, S Yeh, ... The Journal of clinical investigation 120 (6), 2218-2229, 2010 | 125 | 2010 |
E-cadherin couples death receptors to the cytoskeleton to regulate apoptosis M Lu, S Marsters, X Ye, E Luis, L Gonzalez, A Ashkenazi Molecular cell 54 (6), 987-998, 2014 | 120 | 2014 |
A novel snare N-terminal domain revealed by the crystal structure of Sec22b LC Gonzalez, WI Weis, RH Scheller Journal of Biological Chemistry 276 (26), 24203-24211, 2001 | 113 | 2001 |
Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NELL2 A Jaworski, I Tom, RK Tong, HK Gildea, AW Koch, LC Gonzalez, ... Science 350 (6263), 961-965, 2015 | 105 | 2015 |
Paired Immunoglobulin-like Type 2 Receptor Alpha G78R variant alters ligand binding and confers protection to Alzheimer's disease N Rathore, SR Ramani, H Pantua, J Payandeh, T Bhangale, A Wuster, ... PLoS genetics 14 (11), e1007427, 2018 | 82 | 2018 |
The immunoglobulin superfamily receptome defines cancer-relevant networks associated with clinical outcome E Verschueren, B Husain, K Yuen, Y Sun, S Paduchuri, Y Senbabaoglu, ... Cell 182 (2), 329-344. e19, 2020 | 79 | 2020 |
Crystal structure and biophysical properties of a complex between the N-terminal SNARE region of SNAP25 and syntaxin 1a KMS Misura, LC Gonzalez, AP May, RH Scheller, WI Weis Journal of Biological Chemistry 276 (44), 41301-41309, 2001 | 78 | 2001 |
Yeast heat shock transcription factor contains a flexible linker between the DNA-binding and trimerization domains. Implications for DNA binding by trimeric proteins. KE Flick, L Gonzalez Jr, CJ Harrison, HC Nelson Journal of Biological Chemistry 269 (17), 12475-12481, 1994 | 78 | 1994 |