The MAGUK family protein CARD11 is essential for lymphocyte activation H Hara, T Wada, C Bakal, I Kozieradzki, S Suzuki, N Suzuki, M Nghiem, ... Immunity 18 (6), 763-775, 2003 | 404 | 2003 |
Quantitative morphological signatures define local signaling networks regulating cell morphology C Bakal, J Aach, G Church, N Perrimon science 316 (5832), 1753-1756, 2007 | 385 | 2007 |
Genomic screening with RNAi: results and challenges S Mohr, C Bakal, N Perrimon Annual review of biochemistry 79 (1), 37-64, 2010 | 353 | 2010 |
DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression AR Barr, S Cooper, FS Heldt, F Butera, H Stoy, J Mansfeld, B Novák, ... Nature communications 8 (1), 14728, 2017 | 342 | 2017 |
Single-cell dynamics determines response to CDK4/6 inhibition in triple-negative breast cancer US Asghar, AR Barr, R Cutts, M Beaney, I Babina, D Sampath, J Giltnane, ... Clinical Cancer Research 23 (18), 5561-5572, 2017 | 243 | 2017 |
A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes Z Yin, A Sadok, H Sailem, A McCarthy, X Xia, F Li, MA Garcia, L Evans, ... Nature cell biology 15 (7), 860-871, 2013 | 197 | 2013 |
Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions PM Müller, J Rademacher, RD Bagshaw, C Wortmann, C Barth, ... Nature cell biology 22 (4), 498-511, 2020 | 193 | 2020 |
Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death H Okada, C Bakal, A Shahinian, A Elia, A Wakeham, WK Suh, GS Duncan, ... The Journal of experimental medicine 199 (3), 399-410, 2004 | 169 | 2004 |
Phosphorylation networks regulating JNK activity in diverse genetic backgrounds C Bakal, R Linding, F Llense, E Heffern, E Martin-Blanco, T Pawson, ... science 322 (5900), 453-456, 2008 | 143 | 2008 |
Cell shape and the microenvironment regulate nuclear translocation of NF‐κB in breast epithelial and tumor cells JE Sero, HZ Sailem, RC Ardy, H Almuttaqi, T Zhang, C Bakal Molecular systems biology 11 (3), 790, 2015 | 141 | 2015 |
Microenvironmental heterogeneity parallels breast cancer progression: a histology–genomic integration analysis R Natrajan, H Sailem, FK Mardakheh, M Arias Garcia, CJ Tape, ... PLoS medicine 13 (2), e1001961, 2016 | 130 | 2016 |
A dynamical framework for the all-or-none G1/S transition AR Barr, FS Heldt, T Zhang, C Bakal, B Novak Cell systems 2 (1), 27-37, 2016 | 119 | 2016 |
Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis L Stojic, ATL Lun, J Mangei, P Mascalchi, V Quarantotti, AR Barr, C Bakal, ... Nucleic acids research 46 (12), 5950-5966, 2018 | 114 | 2018 |
Nanoneedle-mediated stimulation of cell mechanotransduction machinery CS Hansel, SW Crowder, S Cooper, S Gopal, M João Pardelha da Cruz, ... ACS nano 13 (3), 2913-2926, 2019 | 113 | 2019 |
Mechanistic insight into the microtubule and actin cytoskeleton coupling through dynein-dependent RhoGEF inhibition D Meiri, CB Marshall, MA Greeve, B Kim, M Balan, F Suarez, C Bakal, ... Molecular cell 45 (5), 642-655, 2012 | 95 | 2012 |
A comprehensive model for the proliferation–quiescence decision in response to endogenous DNA damage in human cells FS Heldt, AR Barr, S Cooper, C Bakal, B Novák Proceedings of the National Academy of Sciences 115 (10), 2532-2537, 2018 | 82 | 2018 |
Multiparametric analysis of cell shape demonstrates that β-PIX directly couples YAP activation to extracellular matrix adhesion JE Sero, C Bakal Cell systems 4 (1), 84-96. e6, 2017 | 72 | 2017 |
Cross-talk between Rho and Rac GTPases drives deterministic exploration of cellular shape space and morphological heterogeneity H Sailem, V Bousgouni, S Cooper, C Bakal Open biology 4 (1), 130132, 2014 | 70 | 2014 |
The twin spot generator for differential Drosophila lineage analysis R Griffin, A Sustar, M Bonvin, R Binari, A del Valle Rodriguez, AM Hohl, ... Nature methods 6 (8), 600-602, 2009 | 64 | 2009 |
ALPK1 hotspot mutation as a driver of human spiradenoma and spiradenocarcinoma M Rashid, M van der Horst, T Mentzel, F Butera, I Ferreira, A Pance, ... Nature communications 10 (1), 2213, 2019 | 59 | 2019 |