Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy Y Zhao, TWH Shuen, TB Toh, XY Chan, M Liu, SY Tan, Y Fan, H Yang, ... Gut 67 (10), 1845-1854, 2018 | 180 | 2018 |
Uncovering the mystery of opposite circadian rhythms between mouse and human leukocytes in humanized mice Y Zhao, M Liu, XY Chan, SY Tan, S Subramaniam, Y Fan, E Loh, ... Blood, The Journal of the American Society of Hematology 130 (18), 1995-2005, 2017 | 79 | 2017 |
Hypoxia induces HIF1α-dependent epigenetic vulnerability in triple negative breast cancer to confer immune effector dysfunction and resistance to anti-PD-1 immunotherapy S Ma, Y Zhao, WC Lee, LT Ong, PL Lee, Z Jiang, G Oguz, Z Niu, M Liu, ... Nature communications 13 (1), 4118, 2022 | 78 | 2022 |
Loss of mPer2 increases plasma insulin levels by enhanced glucose-stimulated insulin secretion and impaired insulin clearance in mice Y Zhao, Y Zhang, M Zhou, S Wang, Z Hua, J Zhang FEBS letters 586 (9), 1306-1311, 2012 | 66 | 2012 |
Laxative effects of Salecan on normal and two models of experimental constipated mice M Zhou, P Jia, J Chen, A Xiu, Y Zhao, Y Zhan, P Chen, J Zhang BMC gastroenterology 13, 1-6, 2013 | 63 | 2013 |
The protective role of Per2 against carbon tetrachloride-induced hepatotoxicity P Chen, C Li, W Pang, Y Zhao, W Dong, S Wang, J Zhang The American journal of pathology 174 (1), 63-70, 2009 | 49 | 2009 |
Cancer immunotherapies and humanized mouse drug testing platforms Q Chen, J Wang, WN Liu, Y Zhao Translational oncology 12 (7), 987-995, 2019 | 35 | 2019 |
Analysis and validation of human targets and treatments using a hepatocellular carcinoma–immune humanized mouse model Y Zhao, J Wang, WN Liu, SY Fong, TWH Shuen, M Liu, S Harden, SY Tan, ... Hepatology 74 (3), 1395-1410, 2021 | 32 | 2021 |
The clock gene Per2 is required for normal platelet formation and function Y Zhao, Y Zhang, S Wang, Z Hua, J Zhang Thrombosis research 127 (2), 122-130, 2011 | 29 | 2011 |
The plasma 5′-AMP acts as a potential upstream regulator of hyperglycemia in type 2 diabetic mice Y Zhang, Z Wang, Y Zhao, M Zhao, S Wang, Z Hua, J Zhang American Journal of Physiology-Endocrinology and Metabolism 302 (3), E325-E333, 2012 | 22 | 2012 |
Loss of the clock protein PER2 shortens the erythrocyte life span in mice Q Sun, Y Zhao, Y Yang, X Yang, M Li, X Xu, D Wen, J Wang, J Zhang Journal of Biological Chemistry 292 (30), 12679-12690, 2017 | 18 | 2017 |
The environmental light influences the circulatory levels of retinoic acid and associates with hepatic lipid metabolism W Pang, C Li, Y Zhao, S Wang, W Dong, P Jiang, J Zhang Endocrinology 149 (12), 6336-6342, 2008 | 15 | 2008 |
Increased Reactive Oxygen Species and Cell Cycle Defects Contribute to Anemia in the RASA3 Mutant Mouse Model scat ES Hartman, EC Brindley, J Papoin, SL Ciciotte, Y Zhao, LL Peters, ... Frontiers in Physiology 9, 689, 2018 | 13 | 2018 |
Iron accumulation with age alters metabolic pattern and circadian clock gene expression through the reduction of AMP-modulated histone methylation J Liu, Y Zhao, Z Ding, Y Zhao, T Chen, W Ge, J Zhang Journal of Biological Chemistry 298 (6), 2022 | 7 | 2022 |
Type 2 diabetic mice enter a state of spontaneous hibernation-like suspended animation following accumulation of uric acid Y Zhao, R Cheng, Y Zhao, W Ge, Y Yang, Z Ding, X Xu, Z Wang, Z Wu, ... Journal of Biological Chemistry 297 (4), 2021 | 4 | 2021 |
Differential effects of RASA3 mutations on hematopoiesis are profoundly influenced by genetic background and molecular variant RF Robledo, SL Ciciotte, JH Graber, Y Zhao, AJ Lambert, B Gwynn, ... PLoS genetics 16 (12), e1008857, 2020 | 4 | 2020 |
Diurnal variations in immunity Y Zhao, Q Chen eLS, 1-7, 0 | 1 | |
RASA3 Is Essential for Early Mammalian Hematopoiesis and Modulates ERK Signaling in Terminal Erythropoiesis EC Brindley, RF Robledo, SL Ciciotte, JH Graber, Y Zhao, E Hartman, ... Blood 134, 3505, 2019 | | 2019 |