Structural conversion of neurotoxic amyloid-β1–42 oligomers to fibrils M Ahmed, J Davis, D Aucoin, T Sato, S Ahuja, S Aimoto, JI Elliott, ... Nature structural & molecular biology 17 (5), 561-567, 2010 | 1323 | 2010 |
LRP/amyloid β-peptide interaction mediates differential brain efflux of Aβ isoforms R Deane, Z Wu, A Sagare, J Davis, S Du Yan, K Hamm, F Xu, M Parisi, ... Neuron 43 (3), 333-344, 2004 | 1010 | 2004 |
Protease nexin-II, a potent anti-chymotrypsin, shows identity to amyloid β-protein precursor WEV Nostrand, SL Wagner, M Suzuki, BH Choi, JS Farrow, JW Geddes, ... Nature 341 (6242), 546-549, 1989 | 549 | 1989 |
Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD CA Colton, RT Mott, H Sharpe, Q Xu, WE Van Nostrand, MP Vitek Journal of neuroinflammation 3, 1-12, 2006 | 500 | 2006 |
Early-onset and robust cerebral microvascular accumulation of amyloid β-protein in transgenic mice expressing low levels of a vasculotropic Dutch/Iowa mutant form of amyloid β … J Davis, F Xu, R Deane, G Romanov, ML Previti, K Zeigler, BV Zlokovic, ... Journal of Biological Chemistry 279 (19), 20296-20306, 2004 | 434 | 2004 |
Protease nexin-II (amyloid β-protein precursor): a platelet α-granule protein WE Van Nostrand, AH Schmaier, JS Farrow, DD Cunningham Science 248 (4956), 745-748, 1990 | 402 | 1990 |
Sporadic cerebral amyloid angiopathy J Attems, K Jellinger, DR Thal, W Van Nostrand Neuropathology and applied neurobiology 37 (1), 75-93, 2011 | 397 | 2011 |
Pathogenic effects of D23N Iowa mutant amyloid β-protein WE Van Nostrand, JP Melchor, HS Cho, SM Greenberg, GW Rebeck Journal of Biological Chemistry 276 (35), 32860-32866, 2001 | 317 | 2001 |
SRF and myocardin regulate LRP-mediated amyloid-β clearance in brain vascular cells RD Bell, R Deane, N Chow, X Long, A Sagare, I Singh, JW Streb, H Guo, ... Nature cell biology 11 (2), 143-153, 2009 | 313 | 2009 |
The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease V Hirsch-Reinshagen, LF Maia, BL Burgess, JF Blain, KE Naus, ... Journal of Biological Chemistry 280 (52), 43243-43256, 2005 | 290 | 2005 |
Amyloid β-Protein Inhibits Ubiquitin-dependent Protein Degradation in Vitro (∗) L Gregori, C Fuchs, ME Figueiredo-Pereira, WE Van Nostrand, ... Journal of Biological Chemistry 270 (34), 19702-19708, 1995 | 275 | 1995 |
Decreased levels of soluble amyloid beta-protein precursor in cerebrospinal fluid of live Alzheimer disease patients. WE Van Nostrand, SL Wagner, WR Shankle, JS Farrow, M Dick, ... Proceedings of the National Academy of Sciences 89 (7), 2551-2555, 1992 | 273 | 1992 |
Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World … P Lewczuk, P Riederer, SE O’bryant, MM Verbeek, B Dubois, PJ Visser, ... The world journal of biological psychiatry 19 (4), 244-328, 2018 | 255 | 2018 |
Conformational differences between two amyloid β oligomers of similar size and dissimilar toxicity ARA Ladiwala, J Litt, RS Kane, DS Aucoin, SO Smith, S Ranjan, J Davis, ... Journal of Biological Chemistry 287 (29), 24765-24773, 2012 | 254 | 2012 |
Minocycline reduces microglial activation and improves behavioral deficits in a transgenic model of cerebral microvascular amyloid R Fan, F Xu, ML Previti, J Davis, AM Grande, JK Robinson, ... Journal of Neuroscience 27 (12), 3057-3063, 2007 | 249 | 2007 |
Cerebral microvascular amyloid β protein deposition induces vascular degeneration and neuroinflammation in transgenic mice expressing human vasculotropic mutant amyloid β … J Miao, F Xu, J Davis, I Otte-Höller, MM Verbeek, WE Van Nostrand The American journal of pathology 167 (2), 505-515, 2005 | 233 | 2005 |
Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype N Chow, RD Bell, R Deane, JW Streb, J Chen, A Brooks, W Van Nostrand, ... Proceedings of the National Academy of Sciences 104 (3), 823-828, 2007 | 232 | 2007 |
Enhanced pathologic properties of Dutch-type mutant amyloid beta-protein. J Davis, WE Van Nostrand Proceedings of the National Academy of Sciences 93 (7), 2996-3000, 1996 | 225 | 1996 |
Mechanism of cerebral β‐amyloid angiopathy: murine and cellular models MC Herzig, WE Van Nostrand, M Jucker Brain pathology 16 (1), 40-54, 2006 | 220 | 2006 |
Rapid degeneration of cultured human brain pericytes by amyloid β protein MM Verbeek, RMW De Waal, JJ Schipper, WE Van Nostrand Journal of neurochemistry 68 (3), 1135-1141, 1997 | 197 | 1997 |