Functional therapeutic target validation using pediatric zebrafish xenograft models C Gatzweiler, J Ridinger, S Herter, XF Gerloff, D ElHarouni, Y Berker, ... Cancers 14 (3), 849, 2022 | 22 | 2022 |
Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM H Peterziel, N Jamaladdin, D ElHarouni, XF Gerloff, S Herter, P Fiesel, ... NPJ precision oncology 6 (1), 94, 2022 | 17 | 2022 |
iTReX: Interactive exploration of mono-and combination therapy dose response profiling data D ElHarouni, Y Berker, H Peterziel, A Gopisetty, L Turunen, S Kreth, ... Pharmacological research 175, 105996, 2022 | 15 | 2022 |
A pharmacogenetic study of VDR fok1 and TYMS polymorphisms and their association with glucocorticoid-induced osteonecrosis in Egyptian children with acute lymphoblastic leukemia D ElHarouni, D Yassin, N Ali, S Gohar, I Zaky, H Adwan, I Sidhom Frontiers in Oncology 8, 541, 2018 | 7 | 2018 |
Patient-by-Patient deep transfer learning for drug-response profiling using confocal fluorescence microscopy of pediatric patient-derived tumor-cell spheroids Y Berker, D ElHarouni, H Peterziel, P Fiesel, O Witt, I Oehme, M Schlesner, ... IEEE Transactions on Medical Imaging 41 (12), 3981-3999, 2022 | 6 | 2022 |
Combination drug screen identifies synergistic drug interaction of BCL-XL and class I histone deacetylase inhibitors in MYC-amplified medulloblastoma cells S Zeuner, J Vollmer, R Sigaud, S Oppermann, H Peterziel, D ElHarouni, ... Journal of Neuro-oncology 166 (1), 99-112, 2024 | 5 | 2024 |
Early Metastasis in Colorectal Cancer Poses an Option for New Diagnostic and Treatment Strategies H Adwan, D Elharouni, D Habashy, N Banna, R Georges, A Pervaiz, ... Cancer Metastasis, 2018 | 3 | 2018 |
Synergistic drug combinations for the treatment of MYC amplified medulloblastoma S Zeuner, J Vollmer, S Oppermann, I Oehme, H Peterziel, D ElHarouni, ... Klinische Pädiatrie 235 (06), 2023 | | 2023 |
OTHR-04. DEVELOPMENT OF A FUNCTIONAL PLATFORM FOR REAL-TIME PERSONALIZED DRUG SENSITIVITY PROFILING OF PATIENT-DERIVED 3D FRESH TUMOR TISSUE CULTURES IN THE PEDIATRIC PRECISION … H Peterziel, N Jamaladdin, D ElHarouni, XF Gerloff, S Herter, P Fiesel, ... Neuro-Oncology 25 (Supplement_1), i74-i75, 2023 | | 2023 |
Radiosensitivity in pediatric solid tumors C Gade, R Imle, D ElHarouni, I Oehme, A Banito, KW Pajtler Klinische Pädiatrie 235 (03), 0016, 2023 | | 2023 |
Predicting response to PARP inhibitors in pediatric cancer via synthetic lethal networks M Nagy, F Schischlik, K Wang, NU Nair, EM Gertz, LR Pal, N Jaeger, ... Cancer Research 83 (7_Supplement), 3118-3118, 2023 | | 2023 |
The role of key pharmacodynamic and pharmacokinetic parameters in drug response prediction of pediatric tumors in the precision oncology study INFORM N Jamaladdin | | 2023 |
THE ROLE OF KEY PHARMACODYNAMIC AND PHARMACOKINETIC PARAMETERS IN DRUG RESPONSE PREDICTION OF PEDIATRIC TUMORS IN THE PRECISION ONCOLOGY STUDY INFORM N Jamaladdin, H Peterziel, D ElHarouni, N Jaeger, T Holland-Letz, ... NEURO-ONCOLOGY 24, 33-34, 2022 | | 2022 |
Multiomics analysis of pediatric solid tumors within the INFORM precision oncology study: From functional drug profiling to biomarker identification. D ElHarouni, H Peterziel, K Schramm, T Milde, S Oppermann, I Oehme, ... Journal of Clinical Oncology 40 (16_suppl), 10036-10036, 2022 | | 2022 |
Therapy Response Scoring and Multi-omics Biomarker Identification for Precision Treatments in Pediatric Solid Tumors D ElHarouni Ruprecht-Karls-University Heidelberg, 2022 | | 2022 |
IMAGE-BASED DRUG RESPONSE PROFILING FROM PEDIATRIC TUMOR CELL SPHEROIDS USING PATIENT-BY-PATIENT DEEP TRANSFER LEARNING Y Berker, D ElHarouni, H Peterziel, I Oehme, M Schlesner, O Witt, ... NEURO-ONCOLOGY 23, 36-36, 2021 | | 2021 |
EMBR-11. SYNERGISTIC DRUG COMBINATIONS FOR THE TREATMENT OF MYC AMPLIFIED GROUP 3 MEDULLOBLASTOMA S Zeuner, J Vollmer, H Peterziel, R Sigaud, S Oppermann, D ElHarouni, ... Neuro-Oncology 23 (Supplement_1), i7-i8, 2021 | | 2021 |
Enhancing the effect of class I HDAC inhibition in MYC amplified group 3 medulloblastoma with novel drug combinations S Zeuner, J Ecker, J Vollmer, S Oppermann, I Oehme, H Peterziel, ... Klinische Pädiatrie 232 (03), 2020 | | 2020 |
An integrated bioinformatics pipeline for functional drug response profiling in pediatric precision oncology D ElHarouni, O Witt, M Schlesner, S Oppermann PEMED 2020, 2020 | | 2020 |
Bridging the Gap in Personalized Oncology using Omics Data and Epidemiology D El Harouni, H Adwan, F Nabil Novel Approaches in Cancer Study, 2018 | | 2018 |