| MitoCarta3. 0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations S Rath, R Sharma, R Gupta, T Ast, C Chan, TJ Durham, RP Goodman, ... Nucleic acids research 49 (D1), D1541-D1547, 2021 | 1030 | 2021 |
| Noise can induce bimodality in positive transcriptional feedback loops without bistability TL To, N Maheshri Science 327 (5969), 1142-1145, 2010 | 327 | 2010 |
| A molecular model for intercellular synchronization in the mammalian circadian clock TL To, MA Henson, ED Herzog, FJ Doyle Biophysical journal 92 (11), 3792-3803, 2007 | 193 | 2007 |
| Genetic screen for cell fitness in high or low oxygen highlights mitochondrial and lipid metabolism IH Jain, SE Calvo, AL Markhard, OS Skinner, TL To, T Ast, VK Mootha Cell 181 (3), 716-727. e11, 2020 | 166 | 2020 |
| A compendium of genetic modifiers of mitochondrial dysfunction reveals intra-organelle buffering TL To, AM Cuadros, H Shah, WHW Hung, Y Li, SH Kim, DHF Rubin, ... Cell 179 (5), 1222-1238. e17, 2019 | 126 | 2019 |
| An engineered enzyme that targets circulating lactate to alleviate intracellular NADH:NAD+ imbalance A Patgiri, OS Skinner, Y Miyazaki, G Schleifer, E Marutani, H Shah, ... Nature Biotechnology 38 (3), 309-313, 2020 | 110 | 2020 |
| Rationally designed fluorogenic protease reporter visualizes spatiotemporal dynamics of apoptosis in vivo TL To, BJ Piggott, K Makhijani, D Yu, YN Jan, X Shu Proceedings of the National Academy of Sciences 112 (11), 3338-3343, 2015 | 94 | 2015 |
| Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway CS Asensio, DW Sirkis, JW Maas, K Egami, TL To, FM Brodsky, X Shu, ... Developmental cell 27 (4), 425-437, 2013 | 79 | 2013 |
| Precision optogenetic tool for selective single-and multiple-cell ablation in a live animal model system K Makhijani*, TL To*, R Ruiz-González, C Lafaye, A Royant, X Shu Cell chemical biology 24 (1), 110-119, 2017 | 70 | 2017 |
| Structure‐guided design of a reversible fluorogenic reporter of protein‐protein interactions TL To, Q Zhang, X Shu Protein Science 25 (3), 748-753, 2016 | 54 | 2016 |
| Singlet oxygen triplet energy transfer-based imaging technology for mapping protein–protein proximity in intact cells TL To, MJ Fadul, X Shu Nature communications 5 (1), 4072, 2014 | 54 | 2014 |
| Rational design of a GFP-based fluorogenic caspase reporter for imaging apoptosis in vivo TL To, A Schepis, R Ruiz-González, Q Zhang, D Yu, Z Dong, SR Coughlin, ... Cell chemical biology 23 (7), 875-882, 2016 | 52 | 2016 |
| Combinatorial GxGxE CRISPR screen identifies SLC25A39 in mitochondrial glutathione transport linking iron homeostasis to OXPHOS X Shi, B Reinstadler, H Shah, TL To, K Byrne, L Summer, SE Calvo, ... Nature Communications 13 (1), 2483, 2022 | 50 | 2022 |
| Photoactivatable protein labeling by singlet oxygen mediated reactions TL To, KF Medzihradszky, AL Burlingame, WF DeGrado, H Jo, X Shu Bioorganic & medicinal chemistry letters 26 (14), 3359-3363, 2016 | 35 | 2016 |
| Circadian rhythm: A natural, robust, multi-scale control system FJ Doyle III, R Gunawan, N Bagheri, H Mirsky, TL To Computers & chemical engineering 30 (10-12), 1700-1711, 2006 | 34 | 2006 |
| Congenital hypermetabolism and uncoupled oxidative phosphorylation RD Ganetzky, AL Markhard, I Yee, S Clever, A Cahill, H Shah, Z Grabarek, ... New England Journal of Medicine 387 (15), 1395-1403, 2022 | 16 | 2022 |
| Hypoxia extends lifespan and neurological function in a mouse model of aging RS Rogers, H Wang, TJ Durham, JA Stefely, NA Owiti, AL Markhard, ... PLoS biology 21 (5), e3002117, 2023 | 15 | 2023 |
| Effectors enabling adaptation to mitochondrial complex I loss in Hürthle cell carcinoma RK Gopal, VR Vantaku, A Panda, B Reimer, S Rath, TL To, AS Fisch, ... Cancer discovery 13 (8), 1904-1921, 2023 | 7 | 2023 |
| A genetically encoded system for oxygen generation in living cells AL Markhard, JG McCoy, TL To, VK Mootha Proceedings of the National Academy of Sciences 119 (43), e2207955119, 2022 | 6 | 2022 |
| Combinatorial G x G x E CRISPR screening and functional analysis highlights SLC25A39 in mitochondrial GSH transport X Shi, B Reinstadler, H Shah, TL To, K Byrne, L Summer, SE Calvo, ... bioRxiv, 2021.09. 22.461361, 2021 | 4 | 2021 |
