Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells LF Dong, J Kovarova, M Bajzikova, A Bezawork-Geleta, D Svec, ... Elife 6, e22187, 2017 | 268 | 2017 |
Reactivation of dihydroorotate dehydrogenase-driven pyrimidine biosynthesis restores tumor growth of respiration-deficient cancer cells M Bajzikova, J Kovarova, AR Coelho, S Boukalova, S Oh, K Rohlenova, ... Cell metabolism 29 (2), 399-416. e10, 2019 | 225 | 2019 |
Berberine-induced cardioprotection and Sirt3 modulation in doxorubicin-treated H9c2 cardiomyoblasts AR Coelho, TR Martins, R Couto, C Deus, CV Pereira, RF Simões, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (11 …, 2017 | 73 | 2017 |
Doxorubicin triggers bioenergetic failure and p53 activation in mouse stem cell-derived cardiomyocytes T Cunha-Oliveira, LL Ferreira, AR Coelho, CM Deus, PJ Oliveira Toxicology and applied pharmacology 348, 1-13, 2018 | 46 | 2018 |
Cancer cell metabolism: Rewiring the mitochondrial hub GL Oliveira, AR Coelho, R Marques, PJ Oliveira Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1867 (2), 166016, 2021 | 45 | 2021 |
Replication and ribosomal stress induced by targeting pyrimidine synthesis and cellular checkpoints suppress p53-deficient tumors S Hubackova, E Davidova, S Boukalova, J Kovarova, M Bajzikova, ... Cell death & disease 11 (2), 1-16, 2020 | 40 | 2020 |
MOTS-c reduces myostatin and muscle atrophy signaling H Kumagai, AR Coelho, J Wan, HH Mehta, K Yen, A Huang, H Zempo, ... American Journal of Physiology-Endocrinology and Metabolism 320 (4), E680-E690, 2021 | 37 | 2021 |
Dihydroorotate dehydrogenase inhibitors in SARS‐CoV‐2 infection AR Coelho, PJ Oliveira European journal of clinical investigation, 2020 | 26 | 2020 |
Targeting mitochondrial function for the treatment of breast cancer CM Deus, AR Coelho, TL Serafim, PJ Oliveira Future medicinal chemistry 6 (13), 1499-1513, 2014 | 17 | 2014 |
Mitochondrial Toxicity Induced by Chemotherapeutic Drugs LL Ferreira, AR Coelho, PJ Oliveira, T Cunha‐Oliveira Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants, 593-612, 2018 | 3 | 2018 |
A Selective SARS-CoV-2 Host-Directed Antiviral Targeting Stress Response to Reactive Oxygen Species C Tang, AR Coelho, M Rebelo, H Kiely-Collins, T Carvalho, ... ACS Central Science, 2023 | 2 | 2023 |
Horizontal transfer of mitochondria and dihydroorotate dehydrogenase function in respiration recovery of mtDNA deficient cancer cells LF Dong, J Kovarova, M Bajzikova, A Coelho, S Boukalova, J Rohlena, ... Free Radical Biology and Medicine 120, S53-S54, 2018 | 2 | 2018 |
MOTS-c inhibits high-fat diet-induced muscle wasting by suppressing myostatin expression via the PTEN/AKT/FOXO1 signaling pathway H Kumagai, AR Coelho, J Wan, A Huang, HH Mehta, K Yen, H Zempo, ... The FASEB Journal 34 (S1), 1-1, 2020 | 1 | 2020 |
131. Antiviral NL-CVX1 Efficiently Blocks Infection of SARS-CoV-2 Viral Variants of Concern (VOC) W Su, M Walker, M Rebelo, C Tang, AR Coelho, L Tatalick, M Riley, K Yu, ... Open forum infectious diseases 8 (Supplement_1), S80-S81, 2021 | | 2021 |
Effect of Novel Mitochondria-Targeted Antioxidants in Human Skin Fibroblasts AI Duarte, AR Coelho, D Mena, DF Silva, R Marques, F Cagide, ... EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 51, 43-44, 2021 | | 2021 |
Molecular mechanism of horizontal mitochondrial transfer from stromal cells to cancer cells with damaged mitochondrial DNA ARL Coelho 00500:: Universidade de Coimbra, 2020 | | 2020 |
Mitochondrial dihydroorotate dehydrogenase plays an important role in tumor formation A Coelho, J Kovarova, M Bajzikova, J Rohlena, P Oliveira, J Neuzil EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 49, 55-55, 2019 | | 2019 |
Reactivation of dihydroorotate dehydrogenase by respiration restores tumor growth of mitochondrial DNA-depleted cancer cells J Rohlena, S Boukalova, J Kovarova, M Bajzikova, A Coelho, ... Book of Abstracts, 26, 2018 | | 2018 |
Mitochondrial dihydroorotate dehydrogenase is indispensible for tumor formation AR Coelho, J Kovarova, M Bajzikova, S Boukalova, S Park, L Dong, ... Free Radical Biology and Medicine 120, S48, 2018 | | 2018 |
Horizontal mitochondrial transfer and tumor initiation J Neuzil, M Bajzikova, J Kovarova, A Coelho, J Rohlena, P Oliveira, ... Free Radical Biology and Medicine 108, S10, 2017 | | 2017 |