Development of an acrylate derivative targeting the NLRP3 inflammasome for the treatment of inflammatory bowel disease M Cocco, C Pellegrini, H Martínez-Banaclocha, M Giorgis, E Marini, ... Journal of Medicinal Chemistry 60 (9), 3656-3671, 2017 | 149 | 2017 |
Mass spectrometric characterization of covalent modification of human serum albumin by 4‐hydroxy‐trans‐2‐nonenal G Aldini, L Gamberoni, M Orioli, G Beretta, L Regazzoni, R Maffei Facino, ... Journal of mass spectrometry 41 (9), 1149-1161, 2006 | 141 | 2006 |
Albumin is the main nucleophilic target of human plasma: a protective role against pro-atherogenic electrophilic reactive carbonyl species? G Aldini, G Vistoli, L Regazzoni, L Gamberoni, RM Facino, S Yamaguchi, ... Chemical Research in Toxicology 21 (4), 824-835, 2008 | 138 | 2008 |
Carnosine Attenuates the Development of both Type 2 Diabetes and Diabetic Nephropathy in BTBR ob/ob Mice T Albrecht, M Schilperoort, S Zhang, JD Braun, J Qiu, A Rodriguez, ... Scientific reports 7 (1), 44492, 2017 | 132 | 2017 |
Profiling histidine dipeptides in plasma and urine after ingesting beef, chicken or chicken broth in humans KJ Yeum, M Orioli, L Regazzoni, M Carini, H Rasmussen, RM Russell, ... Amino acids 38, 847-858, 2010 | 111 | 2010 |
Protein carbonylation: 2, 4-dinitrophenylhydrazine reacts with both aldehydes/ketones and sulfenic acids I Dalle-Donne, M Carini, M Orioli, G Vistoli, L Regazzoni, G Colombo, ... Free Radical Biology and Medicine 46 (10), 1411-1419, 2009 | 107 | 2009 |
Oxidative damage in human gingival fibroblasts exposed to cigarette smoke G Colombo, I Dalle-Donne, M Orioli, D Giustarini, R Rossi, M Clerici, ... Free Radical Biology and Medicine 52 (9), 1584-1596, 2012 | 103 | 2012 |
A carnosine analog mitigates metabolic disorders of obesity by reducing carbonyl stress EJ Anderson, G Vistoli, LA Katunga, K Funai, L Regazzoni, TB Monroe, ... The Journal of clinical investigation 128 (12), 5280-5293, 2018 | 95 | 2018 |
A rapid profiling of gallotannins and flavonoids of the aqueous extract of Rhus coriaria L. by flow injection analysis with high-resolution mass spectrometry assisted with … L Regazzoni, E Arlandini, D Garzon, NA Santagati, G Beretta, RM Facino Journal of pharmaceutical and biomedical analysis 72, 202-207, 2013 | 88 | 2013 |
Phenolic profiles and anti-inflammatory activities of sixteen table grape (Vitis vinifera L.) varieties F Colombo, C Di Lorenzo, L Regazzoni, M Fumagalli, E Sangiovanni, ... Food & function 10 (4), 1797-1807, 2019 | 87 | 2019 |
Les Maitres de l’Orge: the proteome content of your beer mug E Fasoli, G Aldini, L Regazzoni, AV Kravchuk, A Citterio, PG Righetti Journal of proteome research 9 (10), 5262-5269, 2010 | 85 | 2010 |
Adductomics pipeline for untargeted analysis of modifications to Cys34 of human serum albumin H Grigoryan, W Edmands, SS Lu, Y Yano, L Regazzoni, AT Iavarone, ... Analytical chemistry 88 (21), 10504-10512, 2016 | 82 | 2016 |
Coffee silver skin as a source of polyphenols: High resolution mass spectrometric profiling of components and antioxidant activity L Regazzoni, F Saligari, C Marinello, G Rossoni, G Aldini, M Carini, ... Journal of Functional Foods 20, 472-485, 2016 | 79 | 2016 |
Design, synthesis, and evaluation of acrylamide derivatives as direct NLRP3 inflammasome inhibitors M Cocco, G Miglio, M Giorgis, D Garella, E Marini, A Costale, L Regazzoni, ... ChemMedChem 11 (16), 1790-1803, 2016 | 78 | 2016 |
Enzymatic and non-enzymatic detoxification of 4-hydroxynonenal: Methodological aspects and biological consequences M Mol, L Regazzoni, A Altomare, G Degani, M Carini, G Vistoli, G Aldini Free Radical Biology and Medicine 111, 328-344, 2017 | 76 | 2017 |
A tandem MS precursor‐ion scan approach to identify variable covalent modification of albumin Cys34: A new tool for studying vascular carbonylation G Aldini, L Regazzoni, M Orioli, I Rimoldi, RM Facino, M Carini Journal of mass spectrometry 43 (11), 1470-1481, 2008 | 75 | 2008 |
A solid-phase extraction procedure coupled to 1H NMR, with chemometric analysis, to seek reliable markers of the botanical origin of honey G Beretta, E Caneva, L Regazzoni, NG Bakhtyari, RM Facino Analytica Chimica Acta 620 (1-2), 176-182, 2008 | 74 | 2008 |
A carnosine intervention study in overweight human volunteers: bioavailability and reactive carbonyl species sequestering effect L Regazzoni, B de Courten, D Garzon, A Altomare, C Marinello, ... Scientific reports 6 (1), 27224, 2016 | 71 | 2016 |
Design, synthesis, and evaluation of carnosine derivatives as selective and efficient sequestering agents of cytotoxic reactive carbonyl species G Vistoli, M Orioli, A Pedretti, L Regazzoni, R Canevotti, G Negrisoli, ... ChemMedChem: Chemistry Enabling Drug Discovery 4 (6), 967-975, 2009 | 69 | 2009 |
Understanding the antioxidant and carbonyl sequestering activity of carnosine: Direct and indirect mechanisms G Aldini, B de Courten, L Regazzoni, E Gilardoni, G Ferrario, G Baron, ... Free radical research 55 (4), 321-330, 2021 | 68 | 2021 |