Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis I Vlodavsky, Y Friedmann, M Elkin, H Aingorn, R Atzmon, R Ishai-Michaeli, ... Nature medicine 5 (7), 793-802, 1999 | 1270 | 1999 |
Regulation, function and clinical significance of heparanase in cancer metastasis and angiogenesis N Ilan, M Elkin, I Vlodavsky The international journal of biochemistry & cell biology 38 (12), 2018-2039, 2006 | 638 | 2006 |
Heparanase as mediator of angiogenesis: mode of action M Elkin, N Ilan, R Ishai-Michaeli, Y Friedmann, O Papo, I Pecker, ... The FASEB Journal 15 (9), 1661-1663, 2001 | 431 | 2001 |
Periodontal pathogens Porphyromonas gingivalis and Fusobacterium nucleatum promote tumor progression in an oral-specific chemical carcinogenesis model AB Gallimidi, S Fischman, B Revach, R Bulvik, A Maliutina, AM Rubinstein, ... Oncotarget 6 (26), 22613, 2015 | 386 | 2015 |
Mammalian heparanase: involvement in cancer metastasis, angiogenesis and normal development I Vlodavsky, O Goldshmidt, E Zcharia, R Atzmon, Z Rangini-Guatta, ... Seminars in cancer biology 12 (2), 121-129, 2002 | 335 | 2002 |
Heparanase gene silencing, tumor invasiveness, angiogenesis, and metastasis E Edovitsky, M Elkin, E Zcharia, T Peretz, I Vlodavsky Journal of the National Cancer Institute 96 (16), 1219-1230, 2004 | 326 | 2004 |
Transgenic expression of mammalian heparanase uncovers physiological functions of heparan sulfate in tissue morphogenesis, vascularization, and feeding behavior E Zcharia, S Metzger, T Chajek‐Shaul, H Aingorn, M Elkin, Y Friedmann, ... The FASEB Journal 18 (2), 252-263, 2004 | 289 | 2004 |
Inhibition of heparanase activity and tumor metastasis by laminarin sulfate and synthetic phosphorothioate oligodeoxynucleotides HQ Miao, M Elkin, E Aingorn, R Ishai‐Michaeli, CA Stein, I Vlodavsky International Journal of Cancer 83 (3), 424-431, 1999 | 282 | 1999 |
Significance of heparanase in cancer and inflammation I Vlodavsky, P Beckhove, I Lerner, C Pisano, A Meirovitz, N Ilan, M Elkin Cancer microenvironment 5, 115-132, 2012 | 281 | 2012 |
Heparanase is essential for the development of diabetic nephropathy in mice N Gil, R Goldberg, T Neuman, M Garsen, E Zcharia, AM Rubinstein, ... Diabetes 61 (1), 208-216, 2012 | 219 | 2012 |
Heparanase: From basic research to therapeutic applications in cancer and inflammation I Vlodavsky, P Singh, I Boyango, L Gutter-Kapon, M Elkin, RD Sanderson, ... Drug resistance updates 29, 54-75, 2016 | 217 | 2016 |
Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice I Lerner, E Hermano, E Zcharia, D Rodkin, R Bulvik, V Doviner, ... The Journal of clinical investigation 121 (5), 1709-1721, 2011 | 214 | 2011 |
Heparanase regulation of cancer, autophagy and inflammation: new mechanisms and targets for therapy RD Sanderson, M Elkin, AC Rapraeger, N Ilan, I Vlodavsky The FEBS journal 284 (1), 42-55, 2017 | 210 | 2017 |
Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis VN Patel, SM Knox, KM Likar, CA Lathrop, R Hossain, S Eftekhari, ... Oxford University Press for The Company of Biologists Limited 134 (23), 4177 …, 2007 | 194 | 2007 |
Heparanase promotes growth, angiogenesis and survival of primary breast tumors I Cohen, O Pappo, M Elkin, T San, R Bar‐Shavit, R Hazan, T Peretz, ... International Journal of Cancer 118 (7), 1609-1617, 2006 | 179 | 2006 |
Mammalian heparanase as mediator of tumor metastasis and angiogenesis. I Vlodavsky, M Elkin, O Pappo, H Aingorn, R Atzmon, R Ishai-Michaeli, ... The Israel Medical Association Journal: IMAJ 2, 37-45, 2000 | 166 | 2000 |
Role of endothelial heparanase in delayed-type hypersensitivity E Edovitsky, I Lerner, E Zcharia, T Peretz, I Vlodavsky, M Elkin Blood 107 (9), 3609-3616, 2006 | 165 | 2006 |
Thymosin β4 increases hair growth by activation of hair follicle stem cells D Philp, M Nguyen, B Scheremeta, S St‐Surin, A M. Villa, A Orgel, ... The FASEB journal 18 (2), 1-16, 2004 | 164 | 2004 |
Stimulation of tumor growth by human soluble intercellular adhesion molecule-1 YS Gho, PN Kim, HC Li, M Elkin, HK Kleinman Cancer research 61 (10), 4253-4257, 2001 | 162 | 2001 |
Regulation of heparanase gene expression by estrogen in breast cancer M Elkin, I Cohen, E Zcharia, A Orgel, Z Guatta-Rangini, T Peretz, ... Cancer research 63 (24), 8821-8826, 2003 | 157 | 2003 |