Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia V Fulci, S Chiaretti, M Goldoni, G Azzalin, N Carucci, S Tavolaro, ... Blood, The Journal of the American Society of Hematology 109 (11), 4944-4951, 2007 | 630 | 2007 |
The estrogen receptor-α-induced microRNA signature regulates itself and its transcriptional response L Castellano, G Giamas, J Jacob, RC Coombes, W Lucchesi, ... Proceedings of the National Academy of Sciences 106 (37), 15732-15737, 2009 | 392 | 2009 |
5′ isomiR variation is of functional and evolutionary importance GC Tan, E Chan, A Molnar, R Sarkar, D Alexieva, IM Isa, S Robinson, ... Nucleic acids research 42 (14), 9424-9435, 2014 | 259 | 2014 |
MicroRNAs cooperatively inhibit a network of tumor suppressor genes to promote pancreatic tumor growth and progression AE Frampton, L Castellano, T Colombo, E Giovannetti, J Krell, J Jacob, ... Gastroenterology 146 (1), 268-277. e18, 2014 | 186 | 2014 |
Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer A Harrod, J Fulton, VTM Nguyen, M Periyasamy, L Ramos-Garcia, CF Lai, ... Oncogene 36 (16), 2286-2296, 2017 | 177 | 2017 |
MicroRNAs targeting oncogenes are down-regulated in pancreatic malignant transformation from benign tumors LR Jiao, AE Frampton, J Jacob, L Pellegrino, J Krell, G Giamas, N Tsim, ... PloS one 7 (2), e32068, 2012 | 171 | 2012 |
Mammosphere formation assay from human breast cancer tissues and cell lines Y Lombardo, A de Giorgio, CR Coombes, J Stebbing, L Castellano JoVE (Journal of Visualized Experiments), e52671, 2015 | 149 | 2015 |
Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer G Giamas, A Filipović, J Jacob, W Messier, H Zhang, D Yang, W Zhang, ... Nature medicine 17 (6), 715-719, 2011 | 149 | 2011 |
Glypican-1 is enriched in circulating-exosomes in pancreatic cancer and correlates with tumor burden AE Frampton, MM Prado, E López-Jiménez, AB Fajardo-Puerta, ... Oncotarget 9 (27), 19006, 2018 | 144 | 2018 |
Visceral adipose tissue immune homeostasis is regulated by the crosstalk between adipocytes and dendritic cell subsets CE Macdougall, EG Wood, J Loschko, V Scagliotti, FC Cassidy, ... Cell metabolism 27 (3), 588-601. e4, 2018 | 143 | 2018 |
Deep sequencing of small RNAs identifies canonical and non-canonical miRNA and endogenous siRNAs in mammalian somatic tissues L Castellano, J Stebbing Nucleic acids research 41 (5), 3339-3351, 2013 | 142 | 2013 |
Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion VTM Nguyen, I Barozzi, M Faronato, Y Lombardo, JH Steel, N Patel, ... Nature communications 6 (1), 10044, 2015 | 137 | 2015 |
miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts L Pellegrino, J Stebbing, VM Braga, AE Frampton, J Jacob, L Buluwela, ... Nucleic acids research 41 (10), 5400-5412, 2013 | 135 | 2013 |
microRNAs with prognostic significance in pancreatic ductal adenocarcinoma: A meta-analysis AE Frampton, J Krell, NB Jamieson, TMH Gall, E Giovannetti, N Funel, ... European journal of cancer 51 (11), 1389-1404, 2015 | 128 | 2015 |
Myocardial MiR-30 downregulation triggered by doxorubicin drives alterations in β-adrenergic signaling and enhances apoptosis L Roca-Alonso, L Castellano, A Mills, AF Dabrowska, MB Sikkel, ... Cell death & disease 6 (5), e1754-e1754, 2015 | 127 | 2015 |
TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression S Ottaviani, J Stebbing, AE Frampton, S Zagorac, J Krell, A de Giorgio, ... Nature communications 9 (1), 1845, 2018 | 117 | 2018 |
miR‐515‐5p controls cancer cell migration through MARK 4 regulation OE Pardo, L Castellano, CE Munro, Y Hu, F Mauri, J Krell, R Lara, ... EMBO reports 17 (4), 570-584, 2016 | 113 | 2016 |
Novel tumour suppressive protein encoded by circular RNA, circ-SHPRH, in glioblastomas S Begum, A Yiu, J Stebbing, L Castellano Oncogene 37 (30), 4055-4057, 2018 | 103 | 2018 |
Emerging roles of competing endogenous RNAs in cancer: insights from the regulation of PTEN A de Giorgio, J Krell, V Harding, J Stebbing, L Castellano Molecular and cellular biology, 2013 | 92 | 2013 |
Growth Arrest-Specific Transcript 5 Associated snoRNA Levels Are Related to p53 Expression and DNA Damage in Colorectal Cancer J Krell, AE Frampton, R Mirnezami, V Harding, A De Giorgio, ... PloS one 9 (6), e98561, 2014 | 91 | 2014 |