| p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes JLE Dean, M Brook, AR Clark, J Saklatvala Journal of Biological Chemistry 274 (1), 264-269, 1999 | 616 | 1999 |
| Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability KR Mahtani, M Brook, JLE Dean, G Sully, J Saklatvala, AR Clark Molecular and cellular biology 21 (19), 6461-6469, 2001 | 560 | 2001 |
| The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation JLE Dean, G Sully, AR Clark, J Saklatvala Cellular signalling 16 (10), 1113-1121, 2004 | 422 | 2004 |
| The 3′ untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR JLE Dean, R Wait, KR Mahtani, G Sully, AR Clark, J Saklatvala Molecular and cellular biology 21 (3), 721-730, 2001 | 373 | 2001 |
| Post-transcriptional regulation of gene expression by mitogen-activated protein kinase p38 AR Clark, JLE Dean, J Saklatvala FEBS letters 546 (1), 37-44, 2003 | 271 | 2003 |
| A p38 MAP kinase inhibitor regulates stability of interleukin-1-induced cyclooxygenase-2 mRNA SH Ridley, JLE Dean, SJ Sarsfield, M Brook, AR Clark, J Saklatvala FEBS letters 439 (1-2), 75-80, 1998 | 264 | 1998 |
| NF-κB suppression by the deubiquitinating enzyme Cezanne: a novel negative feedback loop in pro-inflammatory signaling K Enesa, M Zakkar, H Chaudhury, LA Luong, L Rawlinson, JC Mason, ... Journal of Biological Chemistry 283 (11), 7036-7045, 2008 | 248 | 2008 |
| MAPKAP kinase 2 blocks tristetraprolin-directed mRNA decay by inhibiting CAF1 deadenylase recruitment FP Marchese, A Aubareda, C Tudor, J Saklatvala, AR Clark, JLE Dean Journal of Biological Chemistry 285 (36), 27590-27600, 2010 | 181 | 2010 |
| Control of the expression of inflammatory response genes J Saklatvala, J Dean, A Clark Biochemical Society Symposia 70, 95-106, 2003 | 173 | 2003 |
| p38 Mitogen-activated protein kinase stabilizes mRNAs that contain cyclooxygenase-2 and tumor necrosis factor AU-rich elements by inhibiting deadenylation JLE Dean, SJ Sarsfield, E Tsounakou, J Saklatvala Journal of Biological Chemistry 278 (41), 39470-39476, 2003 | 137 | 2003 |
| Heat shock protein 27 functions in inflammatory gene expression and transforming growth factor-β-activated kinase-1 (TAK1)-mediated signaling KA Alford, S Glennie, BR Turrell, L Rawlinson, J Saklatvala, JLE Dean Journal of biological chemistry 282 (9), 6232-6241, 2007 | 136 | 2007 |
| The p38 MAPK pathway inhibits tristetraprolin-directed decay of interleukin-10 and pro-inflammatory mediator mRNAs in murine macrophages C Tudor, FP Marchese, E Hitti, A Aubareda, L Rawlinson, M Gaestel, ... FEBS letters 583 (12), 1933-1938, 2009 | 124 | 2009 |
| Suppl 2: The p38 MAPK Pathway in Rheumatoid Arthritis: A Sideways Look AR Clark, JLE Dean The open rheumatology journal 6, 209, 2012 | 115 | 2012 |
| Selective tumor necrosis factor receptor I blockade is antiinflammatory and reveals immunoregulatory role of tumor necrosis factor receptor II in collagen‐induced arthritis FE McCann, DP Perocheau, G Ruspi, K Blazek, ML Davies, M Feldmann, ... Arthritis & rheumatology 66 (10), 2728-2738, 2014 | 114 | 2014 |
| Structural and functional dissection of a conserved destabilizing element of cyclo-oxygenase-2 mRNA: evidence against the involvement of AUF-1 [AU-rich element/poly (U)-binding … G Sully, JLE Dean, R Wait, L Rawlinson, T Santalucia, J Saklatvala, ... Biochemical journal 377 (3), 629-639, 2004 | 107 | 2004 |
| Protein kinase cascades in intracellular signalling by interleukin-I and tumour necrosis factor. J Saklatvala, J Dean, A Finch Biochemical Society symposium 64, 63-77, 1999 | 107 | 1999 |
| Cross talk between the Akt and p38α pathways in macrophages downstream of Toll-like receptor signaling VA McGuire, A Gray, CE Monk, SG Santos, K Lee, A Aubareda, J Crowe, ... Molecular and cellular biology 33 (21), 4152-4165, 2013 | 89 | 2013 |
| Post-transcriptional gene regulation by MAP kinases via AU-rich elements A Clark, J Dean, C Tudor, J Saklatvala Front Biosci 14, 847-871, 2009 | 72 | 2009 |
| PARP-14 combines with tristetraprolin in the selective posttranscriptional control of macrophage tissue factor expression MB Iqbal, M Johns, J Cao, Y Liu, SC Yu, GD Hyde, MA Laffan, ... Blood, The Journal of the American Society of Hematology 124 (24), 3646-3655, 2014 | 71 | 2014 |
| Hydrogen peroxide prolongs nuclear localization of NF-κB in activated cells by suppressing negative regulatory mechanisms K Enesa, K Ito, LA Luong, I Thorbjornsen, C Phua, Y To, J Dean, ... Journal of biological chemistry 283 (27), 18582-18590, 2008 | 70 | 2008 |
Anna Aubareda在 kennedy.ox.ac.uk 的电子邮件经过验证
