Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical YH Ding, BM Baker, DN Garboczi, WE Biddison, DC Wiley Immunity 11 (1), 45-56, 1999 | 465 | 1999 |
Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity F Duan, J Duitama, S Al Seesi, CM Ayres, SA Corcelli, AP Pawashe, ... Journal of Experimental Medicine 211 (11), 2231-2248, 2014 | 442 | 2014 |
Evaluation of linked protonation effects in protein binding reactions using isothermal titration calorimetry BM Baker, KP Murphy Biophysical journal 71 (4), 2049-2055, 1996 | 399 | 1996 |
T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility OY Borbulevych, KH Piepenbrink, BE Gloor, DR Scott, RF Sommese, ... Immunity 31 (6), 885-896, 2009 | 234 | 2009 |
Dissecting the energetics of a protein-protein interaction: the binding of ovomucoid third domain to elastase BM Baker, KP Murphy Journal of molecular biology 268 (2), 557-569, 1997 | 206 | 1997 |
The structure and stability of an HLA-A* 0201/octameric tax peptide complex with an empty conserved peptide-N-terminal binding site AR Khan, BM Baker, P Ghosh, WE Biddison, DC Wiley The Journal of Immunology 164 (12), 6398, 2000 | 200 | 2000 |
Prediction of binding energetics from structure using empirical parameterization BM Baker, KP Murphy Methods in enzymology 295, 294-315, 1998 | 180 | 1998 |
Conversion of a T cell antagonist into an agonist by repairing a defect in the TCR/peptide/MHC interface: implications for TCR signaling BM Baker, SJ Gagnon, WE Biddison, DC Wiley Immunity 13 (4), 475-484, 2000 | 179 | 2000 |
TCRs used in cancer gene therapy cross-react with MART-1/Melan-A tumor antigens via distinct mechanisms OY Borbulevych, SM Santhanagopolan, M Hossain, BM Baker The Journal of Immunology 187 (5), 2453-2463, 2011 | 177 | 2011 |
Conformational changes and flexibility in T-cell receptor recognition of peptide–MHC complexes KM Armstrong, KH Piepenbrink, BM Baker Biochemical Journal 415 (Pt 2), 183, 2008 | 173 | 2008 |
Poor immunogenicity of a self/tumor antigen derives from peptide-MHC-I instability and is independent of tolerance Z Yu, MR Theoret, CE Touloukian, DR Surman, SC Garman, ... Journal of Clinical Investigation 114, 551-559, 2004 | 156 | 2004 |
Increased immunogenicity of an anchor-modified tumor-associated antigen is due to the enhanced stability of the peptide/MHC complex: implications for vaccine design OY Borbulevych, TK Baxter, Z Yu, NP Restifo, BM Baker The Journal of Immunology 174 (8), 4812, 2005 | 144 | 2005 |
Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity JJ Adams, S Narayanan, ME Birnbaum, SS Sidhu, SJ Blevins, MH Gee, ... Nature immunology, 2015 | 132 | 2015 |
Two different T cell receptors use different thermodynamic strategies to recognize the same peptide/MHC ligand RL Davis-Harrison, KM Armstrong, BM Baker Journal of molecular biology 346 (2), 533-550, 2005 | 127 | 2005 |
Interactions between CLIP-170, tubulin, and microtubules: implications for the mechanism of Clip-170 plus-end tracking behavior ES Folker, BM Baker, HV Goodson Molecular biology of the cell 16 (11), 5373-5384, 2005 | 115 | 2005 |
Structures of MART-126/27-35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition OY Borbulevych, FK Insaidoo, TK Baxter, DJ Powell Jr, LA Johnson, ... Journal of molecular biology 372 (5), 1123-1136, 2007 | 112 | 2007 |
Prediction of neo-epitope immunogenicity reveals TCR recognition determinants and provides insight into immunoediting J Schmidt, AR Smith, M Magnin, J Racle, JR Devlin, S Bobisse, J Cesbron, ... Cell Reports Medicine 2 (2), 2021 | 106 | 2021 |
Identification of a Crucial Energetic Footprint on the α1 Helix of Human Histocompatibility Leukocyte Antigen (Hla)-A2 That Provides Functional Interactions for Recognition by … BM Baker, RV Turner, SJ Gagnon, DC Wiley, WE Biddison The Journal of experimental medicine 193 (5), 551, 2001 | 100 | 2001 |
Emerging Concepts in TCR Specificity: Rationalizing and (Maybe) Predicting Outcomes NK Singh, TP Riley, SCB Baker, T Borrman, Z Weng, BM Baker The Journal of Immunology 199 (7), 2203-2213, 2017 | 99 | 2017 |
Structural and dynamic control of T‐cell receptor specificity, cross‐reactivity, and binding mechanism BM Baker, DR Scott, SJ Blevins, WF Hawse Immunological Reviews 250 (1), 10-31, 2012 | 98 | 2012 |