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Lu Q. Le, MD, PhD
Lu Q. Le, MD, PhD
Professor and Chair of Dermatology Department, University of Virginia School of Medicine
在 uvahealth.org 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Regional gene therapy with a BMP‐2‐producing murine stromal cell line induces heterotopic and orthotopic bone formation in rodents
JR Lieberman, LQ Le, L Wu, GAM Finerman, A Berk, ON Witte, ...
Journal of Orthopaedic Research 16 (3), 330-339, 1998
4191998
Tumor microenvironment and neurofibromatosis type I: connecting the GAPs
LQ Le, LF Parada
Oncogene 26 (32), 4609-4616, 2007
2422007
Mice lacking the orphan G protein-coupled receptor G2A develop a late-onset autoimmune syndrome
LQ Le, JHS Kabarowski, Z Weng, AB Satterthwaite, ET Harvill, ER Jensen, ...
Immunity 14 (5), 561-571, 2001
2292001
Cell of origin and microenvironment contribution for NF1-associated dermal neurofibromas
LQ Le, T Shipman, DK Burns, LF Parada
Cell stem cell 4 (5), 453-463, 2009
1942009
A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M
Z Weng, AC Fluckiger, S Nisitani, MI Wahl, LQ Le, CA Hunter, AA Fernal, ...
Proceedings of the National Academy of Sciences 95 (21), 12334-12339, 1998
1901998
Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells
AK Ganesan, H Ho, B Bodemann, S Petersen, J Aruri, S Koshy, ...
PLoS genetics 4 (12), e1000298, 2008
1732008
CXCR4/CXCL12 mediate autocrine cell-cycle progression in NF1-associated malignant peripheral nerve sheath tumors
W Mo, J Chen, A Patel, L Zhang, V Chau, Y Li, W Cho, K Lim, J Xu, ...
Cell 152 (5), 1077-1090, 2013
1652013
Contributions of inflammation and tumor microenvironment to neurofibroma tumorigenesis
CP Liao, RC Booker, JP Brosseau, Z Chen, J Mo, E Tchegnon, Y Wang, ...
The Journal of clinical investigation 128 (7), 2848-2861, 2018
1312018
Cells of origin in the embryonic nerve roots for NF1-associated plexiform neurofibroma
Z Chen, C Liu, AJ Patel, CP Liao, Y Wang, LQ Le
Cancer cell 26 (5), 695-706, 2014
1022014
Susceptible stages in Schwann cells for NF1-associated plexiform neurofibroma development
LQ Le, C Liu, T Shipman, Z Chen, U Suter, LF Parada
Cancer research 71 (13), 4686-4695, 2011
1002011
Direct genetic demonstration of Gα13 coupling to the orphan G protein-coupled receptor G2A leading to RhoA-dependent actin rearrangement
JHS Kabarowski, JD Feramisco, LQ Le, JL Gu, SW Luoh, MI Simon, ...
Proceedings of the National Academy of Sciences 97 (22), 12109-12114, 2000
962000
BET bromodomain inhibition triggers apoptosis of NF1-associated malignant peripheral nerve sheath tumors through Bim induction
AJ Patel, CP Liao, Z Chen, C Liu, Y Wang, LQ Le
Cell reports 6 (1), 81-92, 2014
812014
Spatiotemporal loss of NF1 in Schwann cell lineage leads to different types of cutaneous neurofibroma susceptible to modification by the Hippo pathway
Z Chen, J Mo, JP Brosseau, T Shipman, Y Wang, CP Liao, JM Cooper, ...
Cancer Discovery 9 (1), 114-129, 2019
702019
Positron emission tomography imaging analysis of G2A as a negative modifier of lymphoid leukemogenesis initiated by the BCR-ABL oncogene
LQ Le, JHS Kabarowski, S Wong, K Nguyen, SS Gambhir, ON Witte
Cancer Cell 1 (4), 381-391, 2002
632002
Identification of hair shaft progenitors that create a niche for hair pigmentation
CP Liao, RC Booker, SJ Morrison, LQ Le
Genes & development 31 (8), 744-756, 2017
572017
NF1 heterozygosity fosters de novo tumorigenesis but impairs malignant transformation
J Brosseau, C Liao, Y Wang, V Ramani, T Vandergriff, M Lee, A Patel, ...
JOURNAL OF INVESTIGATIVE DERMATOLOGY 139 (5), S63-S63, 2019
532019
NF1 heterozygosity fosters de novo tumorigenesis but impairs malignant transformation
JP Brosseau, CP Liao, Y Wang, V Ramani, T Vandergriff, M Lee, A Patel, ...
Nature communications 9 (1), 5014, 2018
532018
Cutaneous neurofibromas in the genomics era: current understanding and open questions
RJ Allaway, SJC Gosline, S La Rosa, P Knight, A Bakker, J Guinney, ...
British journal of cancer 118 (12), 1539-1548, 2018
512018
Humanized neurofibroma model from induced pluripotent stem cells delineates tumor pathogenesis and developmental origins
J Mo, C Anastasaki, Z Chen, T Shipman, J Papke, K Yin, DH Gutmann, ...
The Journal of clinical investigation 131 (1), 2021
502021
Skin‐derived precursors as a source of progenitors for cutaneous nerve regeneration
Z Chen, S Pradhan, C Liu, LQ Le
Stem Cells 30 (10), 2261-2270, 2012
482012
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