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Wei-Che Hsieh
Wei-Che Hsieh
在 andrew.cmu.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
In utero nanoparticle delivery for site-specific genome editing
AS Ricciardi, R Bahal, JS Farrelly, E Quijano, AH Bianchi, VL Luks, ...
Nature communications 9 (1), 2481, 2018
1542018
Gamma Peptide Nucleic Acids: As Orthogonal Nucleic Acid Recognition Codes for Organizing Molecular Self-Assembly
I Sacui, WC Hsieh, A Manna, B Sahu, DH Ly
Journal of the American Chemical Society 137 (26), 8603-8610, 2015
732015
Anti-tumor activity of miniPEG-γ-modified PNAs to inhibit microRNA-210 for cancer therapy
A Gupta, E Quijano, Y Liu, R Bahal, SE Scanlon, E Song, WC Hsieh, ...
Molecular Therapy-Nucleic Acids 9, 111-119, 2017
702017
Development of oseltamivir phosphonate congeners as anti-influenza agents
TJR Cheng, S Weinheimer, EB Tarbet, JT Jan, YSE Cheng, JJ Shie, ...
Journal of medicinal chemistry 55 (20), 8657-8670, 2012
572012
Design of bivalent nucleic acid ligands for recognition of RNA-repeated expansion associated with Huntington’s disease
SA Thadke, JDR Perera, VM Hridya, K Bhatt, AY Shaikh, WC Hsieh, ...
Biochemistry 57 (14), 2094-2108, 2018
342018
Entropy-driven binding of gut bacterial β-glucuronidase inhibitors ameliorates irinotecan-induced toxicity
HY Lin, CY Chen, TC Lin, LF Yeh, WC Hsieh, S Gao, PA Burnouf, ...
Communications Biology 4 (1), 280, 2021
312021
Design of a “Mini” nucleic acid probe for cooperative binding of an RNA-repeated transcript associated with myotonic dystrophy type 1
WC Hsieh, R Bahal, SA Thadke, K Bhatt, K Sobczak, C Thornton, DH Ly
Biochemistry 57 (6), 907-911, 2018
192018
Orthogonal γPNA dimerization domains empower DNA binders with cooperativity and versatility mimicking that of transcription factor pairs
Z Yu, WC Hsieh, S Asamitsu, K Hashiya, T Bando, DH Ly, H Sugiyama
Chemistry–A European Journal 24 (53), 14183-14188, 2018
172018
Stereochemical conversion of nucleic acid circuits via strand displacement
WC Hsieh, GR Martinez, A Wang, SF Wu, R Chamdia, DH Ly
Communications Chemistry 1 (1), 89, 2018
142018
Bifunctional small molecule-oligonucleotide hybrid as microRNA inhibitor
U Bhattarai, WC Hsieh, H Yan, ZF Guo, AY Shaikh, A Soltani, Y Song, ...
Bioorganic & medicinal chemistry 28 (7), 115394, 2020
122020
RNA‐Templated Concatenation of Triplet Nucleic‐Acid Probe
R Bahal, A Manna, WC Hsieh, SA Thadke, G Sureshkumar, DH Ly
ChemBioChem 19 (7), 674-678, 2018
102018
Substituent position of iminocyclitols determines the potency and selectivity for gut microbial xenobiotic-reactivating enzymes
P Dashnyam, HY Lin, CY Chen, S Gao, LF Yeh, WC Hsieh, Z Tu, CH Lin
Journal of Medicinal Chemistry 63 (9), 4617-4627, 2020
82020
Synthesis of (R)- and (S)-Fmoc-Protected Diethylene Glycol Gamma PNA Monomers with High Optical Purity
WC Hsieh, AY Shaikh, JDR Perera, SA Thadke, DH Ly
The Journal of organic chemistry 84 (3), 1276-1287, 2019
62019
Left-handed gamma-peptide nucleic acids, methods of synthesis and uses therefor
WC Hsieh, I Sacui, A Manna
US Patent 10,851,407, 2020
52020
Template-directed nucleic acid targeting compounds
WC Hsieh, R Bahal
US Patent 11,859,242, 2024
42024
Modified Nucleobases with Uniform H-Bonding Interactions, Homo-and Hetero-Basepair Bias, and Mismatch Discrimination
SA Thadke, AY Shaikh, WC Hsieh, A Nakhi, JD Perera
US Patent App. 16/972,873, 2021
2021
Orthogonal gamma pna dimerization domains empowering dna binders with cooperativity and versatility mimicking that of the transcription factor pairs
WC Hsieh, H Sugiyama, YU Zutao
US Patent App. 16/676,613, 2020
2020
A Robust Method for Preparing Optically Pure MiniPEG-Containing Gamma PNA Monomers
WC Hsieh, DH Ly
Peptide Nucleic Acids: Methods and Protocols, 17-33, 2020
2020
Synthesis and Biomedical Applications of Gamma Peptide Nucleic Acid
W Hsieh
Carnegie Mellon University, 2019
2019
Chapter III: Stereochemical Conversion of Nucleic Acid Circuits via Strand Displacement
WC Hsieh, GR Martinez, A Wang, SF Wu, R Chamdia
Synthesis and Biomedical Applications of Gamma Peptide Nucleic Acid, 107, 2018
2018
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