In utero nanoparticle delivery for site-specific genome editing AS Ricciardi, R Bahal, JS Farrelly, E Quijano, AH Bianchi, VL Luks, ... Nature communications 9 (1), 2481, 2018 | 154 | 2018 |
Gamma Peptide Nucleic Acids: As Orthogonal Nucleic Acid Recognition Codes for Organizing Molecular Self-Assembly I Sacui, WC Hsieh, A Manna, B Sahu, DH Ly Journal of the American Chemical Society 137 (26), 8603-8610, 2015 | 73 | 2015 |
Anti-tumor activity of miniPEG-γ-modified PNAs to inhibit microRNA-210 for cancer therapy A Gupta, E Quijano, Y Liu, R Bahal, SE Scanlon, E Song, WC Hsieh, ... Molecular Therapy-Nucleic Acids 9, 111-119, 2017 | 70 | 2017 |
Development of oseltamivir phosphonate congeners as anti-influenza agents TJR Cheng, S Weinheimer, EB Tarbet, JT Jan, YSE Cheng, JJ Shie, ... Journal of medicinal chemistry 55 (20), 8657-8670, 2012 | 57 | 2012 |
Design of bivalent nucleic acid ligands for recognition of RNA-repeated expansion associated with Huntington’s disease SA Thadke, JDR Perera, VM Hridya, K Bhatt, AY Shaikh, WC Hsieh, ... Biochemistry 57 (14), 2094-2108, 2018 | 34 | 2018 |
Entropy-driven binding of gut bacterial β-glucuronidase inhibitors ameliorates irinotecan-induced toxicity HY Lin, CY Chen, TC Lin, LF Yeh, WC Hsieh, S Gao, PA Burnouf, ... Communications Biology 4 (1), 280, 2021 | 31 | 2021 |
Design of a “Mini” nucleic acid probe for cooperative binding of an RNA-repeated transcript associated with myotonic dystrophy type 1 WC Hsieh, R Bahal, SA Thadke, K Bhatt, K Sobczak, C Thornton, DH Ly Biochemistry 57 (6), 907-911, 2018 | 19 | 2018 |
Orthogonal γPNA dimerization domains empower DNA binders with cooperativity and versatility mimicking that of transcription factor pairs Z Yu, WC Hsieh, S Asamitsu, K Hashiya, T Bando, DH Ly, H Sugiyama Chemistry–A European Journal 24 (53), 14183-14188, 2018 | 17 | 2018 |
Stereochemical conversion of nucleic acid circuits via strand displacement WC Hsieh, GR Martinez, A Wang, SF Wu, R Chamdia, DH Ly Communications Chemistry 1 (1), 89, 2018 | 14 | 2018 |
Bifunctional small molecule-oligonucleotide hybrid as microRNA inhibitor U Bhattarai, WC Hsieh, H Yan, ZF Guo, AY Shaikh, A Soltani, Y Song, ... Bioorganic & medicinal chemistry 28 (7), 115394, 2020 | 12 | 2020 |
RNA‐Templated Concatenation of Triplet Nucleic‐Acid Probe R Bahal, A Manna, WC Hsieh, SA Thadke, G Sureshkumar, DH Ly ChemBioChem 19 (7), 674-678, 2018 | 10 | 2018 |
Substituent position of iminocyclitols determines the potency and selectivity for gut microbial xenobiotic-reactivating enzymes P Dashnyam, HY Lin, CY Chen, S Gao, LF Yeh, WC Hsieh, Z Tu, CH Lin Journal of Medicinal Chemistry 63 (9), 4617-4627, 2020 | 8 | 2020 |
Synthesis of (R)- and (S)-Fmoc-Protected Diethylene Glycol Gamma PNA Monomers with High Optical Purity WC Hsieh, AY Shaikh, JDR Perera, SA Thadke, DH Ly The Journal of organic chemistry 84 (3), 1276-1287, 2019 | 6 | 2019 |
Left-handed gamma-peptide nucleic acids, methods of synthesis and uses therefor WC Hsieh, I Sacui, A Manna US Patent 10,851,407, 2020 | 5 | 2020 |
Template-directed nucleic acid targeting compounds WC Hsieh, R Bahal US Patent 11,859,242, 2024 | 4 | 2024 |
Modified Nucleobases with Uniform H-Bonding Interactions, Homo-and Hetero-Basepair Bias, and Mismatch Discrimination SA Thadke, AY Shaikh, WC Hsieh, A Nakhi, JD Perera US Patent App. 16/972,873, 2021 | | 2021 |
Orthogonal gamma pna dimerization domains empowering dna binders with cooperativity and versatility mimicking that of the transcription factor pairs WC Hsieh, H Sugiyama, YU Zutao US Patent App. 16/676,613, 2020 | | 2020 |
A Robust Method for Preparing Optically Pure MiniPEG-Containing Gamma PNA Monomers WC Hsieh, DH Ly Peptide Nucleic Acids: Methods and Protocols, 17-33, 2020 | | 2020 |
Synthesis and Biomedical Applications of Gamma Peptide Nucleic Acid W Hsieh Carnegie Mellon University, 2019 | | 2019 |
Chapter III: Stereochemical Conversion of Nucleic Acid Circuits via Strand Displacement WC Hsieh, GR Martinez, A Wang, SF Wu, R Chamdia Synthesis and Biomedical Applications of Gamma Peptide Nucleic Acid, 107, 2018 | | 2018 |