Nuclear localisation of Aurora-A: its regulation and significance for Aurora-A functions in cancer FD Naso, D Boi, C Ascanelli, G Pamfil, C Lindon, A Paiardini, ... Oncogene 40 (23), 3917-3928, 2021 | 34 | 2021 |
Selective targeting of non-centrosomal AURKA functions through use of a targeted protein degradation tool R Wang, C Ascanelli, A Abdelbaki, A Fung, T Rasmusson, I Michaelides, ... Communications Biology 4 (1), 640, 2021 | 32 | 2021 |
Pha-680626 is an effective inhibitor of the interaction between aurora-a and n-myc D Boi, F Souvalidou, D Capelli, F Polverino, G Marini, R Montanari, ... International Journal of Molecular Sciences 22 (23), 13122, 2021 | 11 | 2021 |
AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation IA Asteriti, F Polverino, V Stagni, V Sterbini, C Ascanelli, FD Naso, ... Life Science Alliance 6 (5), 2023 | 9 | 2023 |
Revisiting degron motifs in human AURKA required for its targeting by APC/CFZR1 A Abdelbaki, C Ascanelli, CN Okoye, HB Akman, G Janson, M Min, ... Life Science Alliance 6 (2), 2023 | 5 | 2023 |
CRISPR-Cas9-mediated correction of the G189R-PAX2 mutation in induced pluripotent stem cells from a patient with focal segmental glomerulosclerosis P Trionfini, O Ciampi, M Todeschini, C Ascanelli, L Longaretti, L Perico, ... The CRISPR Journal 2 (2), 108-120, 2019 | 4 | 2019 |
A transient modified mRNA encoding Myc and Cyclin T1 induces cardiac regeneration and improves cardiac function after myocardial injury A Boikova, GA Quaife-Ryan, CAP Batho, E Lawrence, H Robinson, ... bioRxiv, 2023.08. 02.551469, 2023 | 2 | 2023 |
HRas and Myc synergistically induce cell cycle progression and apoptosis of murine cardiomyocytes A Boikova, MJ Bywater, GA Quaife-Ryan, J Straube, L Thompson, ... Frontiers in Cardiovascular Medicine 9, 948281, 2022 | 2 | 2022 |
Manipulating Myc for reparative regeneration C Ascanelli, R Dahir, CH Wilson Frontiers in Cell and Developmental Biology 12, 1357589, 2024 | | 2024 |
A flexible, high-throughput system for studying mRNA translation kinetics in vitro and in cellulo with HiBit technology C Ascanelli, E Lawrence, CAP Batho, CH Wilson bioRxiv, 2024.06. 27.600987, 2024 | | 2024 |
Development of a single-cell fluorescence-based sensor to investigate Myc protein stability C Ascanelli | | 2022 |
A Focused Small-Molecule Screen Identifies PHA-680626 as an Amphosteric Inhibitor Disrupting the Interaction between Aurora-A and N-Myc F Souvalidou, D Boi, R Montanari, F Polverino, G Marini, D Capelli, ... bioRxiv, 2021.03. 10.433854, 2021 | | 2021 |
Selective targeting of non-centrosomal AURKA functions through use of a novel targeted protein degradation tool R Wang, A Abdelbaki, C Ascanelli, A Fung, T Rasmusson, K Roberts, ... bioRxiv, 2020.07. 22.215814, 2020 | | 2020 |