Sulfonium, an underestimated moiety for structural modification, alters the antibacterial profile of vancomycin against multidrug‐resistant bacteria D Guan, F Chen, Y Qiu, B Jiang, L Gong, L Lan, W Huang Angewandte Chemie 131 (20), 6750-6754, 2019 | 71 | 2019 |
Direct cardiac actions of the sodium glucose co‐transporter 2 inhibitor empagliflozin improve myocardial oxidative phosphorylation and attenuate pressure‐overload heart failure X Li, Q Lu, Y Qiu, JM do Carmo, Z Wang, AA da Silva, A Mouton, ... Journal of the American Heart Association 10 (6), e018298, 2021 | 68 | 2021 |
Extra Sugar on Vancomycin: New Analogues for Combating Multidrug-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococci D Guan, F Chen, L Xiong, F Tang, Faridoon, Y Qiu, N Zhang, L Gong, J Li, ... Journal of Medicinal Chemistry 61 (1), 286-304, 2018 | 54 | 2018 |
Migration of PIP2 lipids on voltage-gated potassium channel surface influences channel deactivation L Chen, Q Zhang, Y Qiu, Z Li, Z Chen, H Jiang, Y Li, H Yang Scientific Reports 5 (1), 15079, 2015 | 40 | 2015 |
Selective activation of TWIK-related acid-sensitive K+ 3 subunit–containing channels is analgesic in rodent models P Liao, Y Qiu, Y Mo, J Fu, Z Song, L Huang, S Bai, Y Wang, JJ Zhu, F Tian, ... Science Translational Medicine 11 (519), eaaw8434, 2019 | 29 | 2019 |
TREK channel family activator with a well-defined structure–activation relationship for pain and neurogenic inflammation Y Qiu, L Huang, J Fu, C Han, J Fang, P Liao, Z Chen, Y Mo, P Sun, D Liao, ... Journal of Medicinal Chemistry 63 (7), 3665-3677, 2020 | 22 | 2020 |
The Mechanism by Which Luteolin Disrupts the Cytoplasmic Membrane of Methicillin-Resistant Staphylococcus aureus T Zhang, Y Qiu, Q Luo, L Zhao, X Yan, Q Ding, H Jiang, H Yang The Journal of Physical Chemistry B 122 (4), 1427-1438, 2018 | 20 | 2018 |
A small-molecule compound selectively activates K2P channel TASK-3 by acting at two distant clusters of residues F Tian, Y Qiu, X Lan, M Li, H Yang, Z Gao Molecular pharmacology 96 (1), 26-35, 2019 | 19 | 2019 |
svglite: an “SVG” graphics device. R package version 2.0. 0 H Wickham, L Henry, TL Pedersen, TJ Luciani, M Decorde, V Lise, T Plate, ... | 16 | 2021 |
Design, synthesis, and biological evaluation of 2-(phenoxyaryl)-3-urea derivatives as novel P2Y1 receptor antagonists J Peng, L Zhao, L Wang, H Chen, Y Qiu, J Wang, H Yang, J Liu, H Liu European Journal of Medicinal Chemistry 158, 302-310, 2018 | 15 | 2018 |
Artificial intelligence for drug discovery and development in Alzheimer's disease Y Qiu, F Cheng Current Opinion in Structural Biology 85, 102776, 2024 | 9 | 2024 |
MBOAT7-driven lysophosphatidylinositol acylation in adipocytes contributes to systemic glucose homeostasis WJ Massey, V Varadharajan, R Banerjee, AL Brown, AJ Horak, RC Hohe, ... Journal of Lipid Research 64 (4), 2023 | 9 | 2023 |
Concentration dependent effects of Ca2+ and Mg2+ on the phosphatidylethanolamine-phosphatidylglycerol bilayer T ZHANG, Y QIU, Q LUO, X CHENG, L ZHAO, X YAN, B PENG Acta Phys.-Chim. Sin 35 (8), 840-849, 2019 | 4 | 2019 |
Comprehensive characterization of multi-omic landscapes between gut-microbiota metabolites and the G-protein-coupled receptors in Alzheimer’s disease Y Qiu, Y Hou, Y Zhou, J Xu, M Bykova, JB Leverenz, AA Pieper, ... bioRxiv, 2022.09. 20.508759, 2022 | 2 | 2022 |
Systematic characterization of multi-omics landscape between gut microbial metabolites and GPCRome in Alzheimer’s disease Y Qiu, Y Hou, D Gohel, Y Zhou, J Xu, M Bykova, Y Yang, JB Leverenz, ... Cell Reports 43 (5), 2024 | 1 | 2024 |
Structurally-informed human interactome reveals proteome-wide perturbations by disease mutations D Xiong, Y Qiu, J Zhao, Y Zhou, D Lee, S Gupta, M Torres, W Lu, S Liang, ... bioRxiv, 2023 | 1 | 2023 |
Multi-omic landscapes between gut microbial metabolites and G-protein-coupled receptors in Alzheimer’s disease Y Qiu, Y Hou, D Gohel, Y Zhou, M Bykova, Y Yang, JB Leverenz, ... Alzheimer's Association International Conference, 2024 | | 2024 |
A Molecular Video-derived Foundation Model Streamlines Scientific Drug Discovery F Cheng, H Xiang, L Zeng, L Hou, K Li, Z Fu, Y Qiu, R Nussinov, J Hu, ... | | 2024 |
A Deep Learning Framework Streamlines Computational Drug Discovery Via Combining Molecular Image and Protein Structural Representation Y Yang, Y Qiu, J Hu, M Rosen-Zvi, Q Guan, F Cheng Available at SSRN 4710836, 0 | | |