| Regulation of CYP1A1 by heavy metals and consequences for drug metabolism A Anwar-Mohamed, RH Elbekai, AOS El-Kadi Expert opinion on drug metabolism & toxicology 5 (5), 501-521, 2009 | 109 | 2009 |
| The anti-inflammatory properties of phytochemicals and their effects on epigenetic mechanisms involved in TLR4/NF-κB-mediated inflammation HA Saleh, MH Yousef, A Abdelnaser Frontiers in immunology 12, 606069, 2021 | 108 | 2021 |
| Acute doxorubicin cardiotoxicity alters cardiac cytochrome P450 expression and arachidonic acid metabolism in rats BNM Zordoky, A Anwar-Mohamed, ME Aboutabl, AOS El-Kadi Toxicology and applied pharmacology 242 (1), 38-46, 2010 | 108 | 2010 |
| Acute doxorubicin toxicity differentially alters cytochrome P450 expression and arachidonic acid metabolism in rat kidney and liver BNM Zordoky, A Anwar-Mohamed, ME Aboutabl, AOS El-Kadi Drug Metabolism and Disposition 39 (8), 1440-1450, 2011 | 99 | 2011 |
| Sulforaphane induces CYP1A1 mRNA, protein, and catalytic activity levels via an AhR-dependent pathway in murine hepatoma Hepa 1c1c7 and human HepG2 cells A Anwar-Mohamed, AOS El-Kadi Cancer letters 275 (1), 93-101, 2009 | 75 | 2009 |
| The effect of Nrf2 knockout on the constitutive expression of drug metabolizing enzymes and transporters in C57Bl/6 mice livers A Anwar-Mohamed, OS Degenhardt, MAM El Gendy, JM Seubert, ... Toxicology in Vitro 25 (4), 785-795, 2011 | 69 | 2011 |
| Oxidative stress attenuates lipid synthesis and increases mitochondrial fatty acid oxidation in hepatoma cells infected with hepatitis C virus DN Douglas, CH Pu, JT Lewis, R Bhat, A Anwar-Mohamed, M Logan, ... Journal of biological chemistry 291 (4), 1974-1990, 2016 | 61 | 2016 |
| Alteration of cardiac cytochrome P450-mediated arachidonic acid metabolism in response to lipopolysaccharide-induced acute systemic inflammation A Anwar-mohamed, BNM Zordoky, ME Aboutabl, AOS El-Kadi Pharmacological research 61 (5), 410-418, 2010 | 61 | 2010 |
| Clinical implications of 20-hydroxyeicosatetraenoic acid in the kidney, liver, lung and brain: an emerging therapeutic target OH Elshenawy, SM Shoieb, A Mohamed, AOS El-Kadi Pharmaceutics 9 (1), 9, 2017 | 57 | 2017 |
| A human ether-á-go-go-related (hERG) ion channel atomistic model generated by long supercomputer molecular dynamics simulations and its use in predicting drug cardiotoxicity A Anwar-Mohamed, KH Barakat, R Bhat, SY Noskov, DL Tyrrell, ... Toxicology letters 230 (3), 382-392, 2014 | 52 | 2014 |
| Secondary cytotoxicity mediated by alveolar macrophages: a contribution to the total efficacy of nanoparticles in lung cancer therapy? KMHD Al-Hallak, S Azarmi, A Anwar-Mohamed, WH Roa, R Löbenberg European Journal of Pharmaceutics and Biopharmaceutics 76 (1), 112-119, 2010 | 51 | 2010 |
| A refined model of the HCV NS5A protein bound to daclatasvir explains drug-resistant mutations and activity against divergent genotypes KH Barakat, A Anwar-Mohamed, JA Tuszynski, MJ Robins, DL Tyrrell, ... Journal of chemical information and modeling 55 (2), 362-373, 2015 | 50 | 2015 |
| The tumor suppressor gene, RASSF1A, is essential for protection against inflammation-induced injury M Gordon, M El-Kalla, Y Zhao, Y Fiteih, J Law, N Volodko, A Mohamed, ... PloS one 8 (10), e75483, 2013 | 50 | 2013 |
| Determination of the dominant arachidonic acid cytochrome p450 monooxygenases in rat heart, lung, kidney, and liver: protein expression and metabolite kinetics AA El-Sherbeni, ME Aboutabl, BNM Zordoky, A Anwar-Mohamed, ... The AAPS journal 15, 112-122, 2013 | 49 | 2013 |
| Differential modulation of aryl hydrocarbon receptor regulated enzymes by arsenite in the kidney, lung, and heart of C57BL/6 mice A Anwar-Mohamed, G Abdelhamid, IEA Amara, AOS El-Kadi Archives of toxicology 86, 897-910, 2012 | 40 | 2012 |
| The p38 MAPK inhibitor SB203580 induces cytochrome P450 1A1 gene expression in murine and human hepatoma cell lines through ligand-dependent aryl hydrocarbon receptor activation HM Korashy, A Anwar-Mohamed, AA Soshilov, MS Denison, AOS El-Kadi Chemical research in toxicology 24 (9), 1540-1548, 2011 | 40 | 2011 |
| Arsenite down-regulates cytochrome P450 1A1 at the transcriptional and posttranslational levels in human HepG2 cells A Anwar-Mohamed, AOS El-Kadi Free Radical Biology and Medicine 48 (10), 1399-1409, 2010 | 40 | 2010 |
| Induction of cytochrome P450 1a1 by the food flavoring agent, maltol A Anwar-Mohamed, AOS El-Kadi Toxicology in vitro 21 (4), 685-690, 2007 | 40 | 2007 |
| 20-Hydroxyeicosatetraenoic acid is a potential therapeutic target in cardiovascular diseases O H Elshenawy, A Anwar-Mohamed, A OS El-Kadi Current Drug Metabolism 14 (6), 706-719, 2013 | 38 | 2013 |
| Design and synthesis of ibuprofen-quinoline conjugates as potential anti-inflammatory and analgesic drug candidates AM Ghanim, AS Girgis, BM Kariuki, N Samir, MF Said, A Abdelnaser, ... Bioorganic chemistry 119, 105557, 2022 | 37 | 2022 |
