The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells M Van de Wetering, E Sancho, C Verweij, W De Lau, I Oving, A Hurlstone, ... Cell 111 (2), 241-250, 2002 | 2533 | 2002 |
The chromatin remodelling factor Brg-1 interacts with β-catenin to promote target gene activation N Barker, A Hurlstone, H Musisi, A Miles, M Bienz, H Clevers The EMBO journal 20 (17), 4935-4943, 2001 | 583 | 2001 |
MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis S Nicoli, C Standley, P Walker, A Hurlstone, KE Fogarty, ND Lawson Nature 464 (7292), 1196-1200, 2010 | 546 | 2010 |
The Wnt/β-catenin pathway regulates cardiac valve formation AFL Hurlstone, APG Haramis, E Wienholds, H Begthel, J Korving, ... Nature 425 (6958), 633-637, 2003 | 468 | 2003 |
T‐cell factors: turn‐ons and turn‐offs A Hurlstone, H Clevers The EMBO journal, 2002 | 300 | 2002 |
Live imaging of innate immune cell sensing of transformed cells in zebrafish larvae: parallels between tumor initiation and wound inflammation Y Feng, C Santoriello, M Mione, A Hurlstone, P Martin PLoS biology 8 (12), e1000562, 2010 | 241 | 2010 |
BRAF as therapeutic target in melanoma C Wellbrock, A Hurlstone Biochemical pharmacology 80 (5), 561-567, 2010 | 231 | 2010 |
Heterogeneous tumor subpopulations cooperate to drive invasion A Chapman, LF del Ama, J Ferguson, J Kamarashev, C Wellbrock, ... Cell reports 8 (3), 688-695, 2014 | 220 | 2014 |
The transcription factor AP-1 is required for EGF-induced activation of rho-like GTPases, cytoskeletal rearrangements, motility, and in vitro invasion of A431 cells A Malliri, M Symons, RF Hennigan, AFL Hurlstone, RF Lamb, T Wheeler, ... The Journal of cell biology 143 (4), 1087-1099, 1998 | 184 | 1998 |
Adenomatous polyposis coli‐deficient zebrafish are susceptible to digestive tract neoplasia APG Haramis, A Hurlstone, Y van der Velden, H Begthel, M van den Born, ... EMBO reports 7 (4), 444-449, 2006 | 180 | 2006 |
Analysis of the CAVEOLIN-1 gene at human chromosome 7q31. 1 in primary tumours and tumour-derived cell lines AFL Hurlstone, G Reid, JR Reeves, J Fraser, G Strathdee, M Rahilly, ... Oncogene 18 (10), 1881-1890, 1999 | 167 | 1999 |
Kita driven expression of oncogenic HRAS leads to early onset and highly penetrant melanoma in zebrafish C Santoriello, E Gennaro, V Anelli, M Distel, A Kelly, RW Köster, ... PloS one 5 (12), e15170, 2010 | 152 | 2010 |
Small molecule inhibition of ERK dimerization prevents tumorigenesis by RAS-ERK pathway oncogenes A Herrero, A Pinto, P Colón-Bolea, B Casar, M Jones, L Agudo-Ibáñez, ... Cancer cell 28 (2), 170-182, 2015 | 147 | 2015 |
The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development A Malliri, TP Rygiel, RA Van Der Kammen, JY Song, R Engers, ... Journal of Biological Chemistry 281 (1), 543-548, 2006 | 142 | 2006 |
CD4-transgenic zebrafish reveal tissue-resident Th2-and regulatory T cell–like populations and diverse mononuclear phagocytes CT Dee, RT Nagaraju, EI Athanasiadis, C Gray, L Fernandez del Ama, ... The Journal of Immunology 197 (9), 3520-3530, 2016 | 136 | 2016 |
The TES gene at 7q31. 1 is methylated in tumours and encodes a novel growth-suppressing LIM domain protein ES Tobias, AFL Hurlstone, E MacKenzie, R McFarlane, DM Black Oncogene 20 (22), 2844-2853, 2001 | 130 | 2001 |
Implication of BRG1 and cdk9 in the STAT3-mediated activation of the p21waf1 gene S Giraud, A Hurlstone, S Avril, O Coqueret Oncogene 23 (44), 7391-7398, 2004 | 124 | 2004 |
Zebrafish: a new companion for translational research in oncology J Barriuso, R Nagaraju, A Hurlstone Clinical Cancer Research 21 (5), 969-975, 2015 | 118 | 2015 |
α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3 NR Paul, JL Allen, A Chapman, M Morlan-Mairal, E Zindy, G Jacquemet, ... Journal of Cell Biology 210 (6), 1013-1031, 2015 | 113 | 2015 |
Effect of SMURF2 targeting on susceptibility to MEK inhibitors in melanoma MP Smith, J Ferguson, I Arozarena, R Hayward, R Marais, A Chapman, ... Journal of the National Cancer Institute 105 (1), 33-46, 2013 | 112 | 2013 |