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Adam Hurlstone
Adam Hurlstone
Associate Professor, The University of Manchester
在 manchester.ac.uk 的电子邮件经过验证 - 首页
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The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
M Van de Wetering, E Sancho, C Verweij, W De Lau, I Oving, A Hurlstone, ...
Cell 111 (2), 241-250, 2002
25332002
The chromatin remodelling factor Brg-1 interacts with β-catenin to promote target gene activation
N Barker, A Hurlstone, H Musisi, A Miles, M Bienz, H Clevers
The EMBO journal 20 (17), 4935-4943, 2001
5832001
MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis
S Nicoli, C Standley, P Walker, A Hurlstone, KE Fogarty, ND Lawson
Nature 464 (7292), 1196-1200, 2010
5462010
The Wnt/β-catenin pathway regulates cardiac valve formation
AFL Hurlstone, APG Haramis, E Wienholds, H Begthel, J Korving, ...
Nature 425 (6958), 633-637, 2003
4682003
T‐cell factors: turn‐ons and turn‐offs
A Hurlstone, H Clevers
The EMBO journal, 2002
3002002
Live imaging of innate immune cell sensing of transformed cells in zebrafish larvae: parallels between tumor initiation and wound inflammation
Y Feng, C Santoriello, M Mione, A Hurlstone, P Martin
PLoS biology 8 (12), e1000562, 2010
2412010
BRAF as therapeutic target in melanoma
C Wellbrock, A Hurlstone
Biochemical pharmacology 80 (5), 561-567, 2010
2312010
Heterogeneous tumor subpopulations cooperate to drive invasion
A Chapman, LF del Ama, J Ferguson, J Kamarashev, C Wellbrock, ...
Cell reports 8 (3), 688-695, 2014
2202014
The transcription factor AP-1 is required for EGF-induced activation of rho-like GTPases, cytoskeletal rearrangements, motility, and in vitro invasion of A431 cells
A Malliri, M Symons, RF Hennigan, AFL Hurlstone, RF Lamb, T Wheeler, ...
The Journal of cell biology 143 (4), 1087-1099, 1998
1841998
Adenomatous polyposis coli‐deficient zebrafish are susceptible to digestive tract neoplasia
APG Haramis, A Hurlstone, Y van der Velden, H Begthel, M van den Born, ...
EMBO reports 7 (4), 444-449, 2006
1802006
Analysis of the CAVEOLIN-1 gene at human chromosome 7q31. 1 in primary tumours and tumour-derived cell lines
AFL Hurlstone, G Reid, JR Reeves, J Fraser, G Strathdee, M Rahilly, ...
Oncogene 18 (10), 1881-1890, 1999
1671999
Kita driven expression of oncogenic HRAS leads to early onset and highly penetrant melanoma in zebrafish
C Santoriello, E Gennaro, V Anelli, M Distel, A Kelly, RW Köster, ...
PloS one 5 (12), e15170, 2010
1522010
Small molecule inhibition of ERK dimerization prevents tumorigenesis by RAS-ERK pathway oncogenes
A Herrero, A Pinto, P Colón-Bolea, B Casar, M Jones, L Agudo-Ibáñez, ...
Cancer cell 28 (2), 170-182, 2015
1472015
The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development
A Malliri, TP Rygiel, RA Van Der Kammen, JY Song, R Engers, ...
Journal of Biological Chemistry 281 (1), 543-548, 2006
1422006
CD4-transgenic zebrafish reveal tissue-resident Th2-and regulatory T cell–like populations and diverse mononuclear phagocytes
CT Dee, RT Nagaraju, EI Athanasiadis, C Gray, L Fernandez del Ama, ...
The Journal of Immunology 197 (9), 3520-3530, 2016
1362016
The TES gene at 7q31. 1 is methylated in tumours and encodes a novel growth-suppressing LIM domain protein
ES Tobias, AFL Hurlstone, E MacKenzie, R McFarlane, DM Black
Oncogene 20 (22), 2844-2853, 2001
1302001
Implication of BRG1 and cdk9 in the STAT3-mediated activation of the p21waf1 gene
S Giraud, A Hurlstone, S Avril, O Coqueret
Oncogene 23 (44), 7391-7398, 2004
1242004
Zebrafish: a new companion for translational research in oncology
J Barriuso, R Nagaraju, A Hurlstone
Clinical Cancer Research 21 (5), 969-975, 2015
1182015
α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3
NR Paul, JL Allen, A Chapman, M Morlan-Mairal, E Zindy, G Jacquemet, ...
Journal of Cell Biology 210 (6), 1013-1031, 2015
1132015
Effect of SMURF2 targeting on susceptibility to MEK inhibitors in melanoma
MP Smith, J Ferguson, I Arozarena, R Hayward, R Marais, A Chapman, ...
Journal of the National Cancer Institute 105 (1), 33-46, 2013
1122013
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